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    Wyświetlanie 1-11 z 11
    Tytuł:
    Comparative analysis of socioeconomic, behavioral and biological factors between healthy patients and patients with newly diagnosed diabetes in the Lubuskie Voivodeship
    Autorzy:
    Bonikowska, I.
    Jasik-Pyzdrowska, J.
    Szwamel, K.
    Powiązania:
    https://bibliotekanauki.pl/articles/2087637.pdf
    Data publikacji:
    2020
    Wydawca:
    Uniwersytet Opolski. Instytut Nauk o Zdrowiu
    Tematy:
    patients
    type 2 diabetes mellitus
    prediabetic state
    Opis:
    Background: The most effective way to prevent an increasing diabetic population lies in early detection of risk factors and diagnosis of carbohydrate metabolism disorders. Aim of the study: The study aimed at determining socio-economic variables, lifestyle behaviours and biological factors differentiating patients with newly diagnosed diabetes from diabetes-free individuals. Material and methods: Assessment of diabetic vs. non-diabetic individuals was performed according to the American criteria issued by the Commission on Social Determinants of Health as well as the FINDRISC form, which helps identify patients who are at risk of developing type 2 diabetes on the basis of multi-factorial determinants of its development. The research was conducted in 2018 among 1167 primary health care patients from Lubuskie Voivodeship using a diagnostic survey method which interviewed the respondents according to the FINDRISC standard questionnaire. Results: The group of healthy patients was similar to the group of patients with newly diagnosed diabetes with respect to variables such as age (p=0.713), sex (p=1), place of residence (p=1), level of education (p=0.076), professional activity (p=0.758), BMI (p=0.133), waist measurement (p=0.665), frequency of fruit and vegetables intake (p=0.572), frequency of taking hypotensive medications (p=0.176), frequency of diabetes occurrence in the family history (p=0.227) and physical activity (p=0.321). Conclusions: Early detection of carbohydrate metabolism disorders, with the use of standardised tools that assess diabetes development, appears to be essential in the prevention of this disorder. Therefore, there is a strong need to create a tool adjusted to socio-demographic factors such as geographical location, economic conditions and lifestyle. Additionally, active and massive screening for carbohydrate metabolism disorders in patients with a low risk of diabetes seems to be crucial in its prevention.
    Źródło:
    Medical Science Pulse; 2020, 14, 3; 55-63
    2544-1558
    2544-1620
    Pojawia się w:
    Medical Science Pulse
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Stigma and its relationship with life satisfaction in patients with type 2 diabetes mellitus
    Autorzy:
    Turen, Sevda
    Yurtsever, Melike
    Powiązania:
    https://bibliotekanauki.pl/articles/40418503.pdf
    Data publikacji:
    2024-03-30
    Wydawca:
    Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
    Tematy:
    life satisfaction
    stigma
    type 2 diabetes mellitus
    Opis:
    Introduction and aim. This study aims to determine the level of stigma in patients with type 2 diabetes mellitus (T2DM) and evaluate its relationship with their life satisfaction. Material and methods. This is a descriptive and cross-sectional study conducted in a single tertiary care center. Two hundred and ten patients ≥18 years old diagnosed with T2DM were included in this study. The relationship between the “Type 2 diabetes stigma assessment scale” and the “Satisfaction with life scale” was assessed using Pearson correlation analysis. Results. The average age of the participants was 54.85±15.81 years. The majority of patients reported adherence to diabetes treatment and having comorbidities. Stigma levels were higher in patients ≤65 years, those with less than a high school education, and those receiving insulin or oral anti-diabetic treatment, but lower with a T2DM diagnosis duration of ≤ 5 years (p<0.05). Life satisfaction was influenced by age, education status, economic status, adherence to treatment, dietary compliance, and the presence of comorbidities. A moderately negative relationship between stigma level and life satisfaction was identified. Conclusion. The study’s results indicate that an increase in stigma level is associated with a decrease in life satisfaction in patients with type 2 diabetes mellitus.
    Źródło:
    European Journal of Clinical and Experimental Medicine; 2024, 22, 1; 128-133
    2544-2406
    2544-1361
    Pojawia się w:
    European Journal of Clinical and Experimental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Prevalence of depression in Indian patients with type 2 diabetes mellitus and/or hypertension: DEPTH Study
    Autorzy:
    Lalwani, Raj Kumar
    Shah, Jayesh Dashrathlal
    Chatterjea, Tapas
    Nadakuduru, Papa Rao
    Erande, Suhas
    Powiązania:
    https://bibliotekanauki.pl/articles/454720.pdf
    Data publikacji:
    2019
    Wydawca:
    Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
    Tematy:
    comorbidity
    diabetes
    depression
    hypertension prevalence
    type 2 diabetes mellitus
    Opis:
    ABSTRACT Introduction. Depression, a common psychiatric mood disorder, is a leading cause of disability and a significant contributor to the overall global burden of disease. Aim. To determine the prevalence of depression in patients with controlled and uncontrolled type-2 diabetes mellitus (T2DM) and/or hypertension (HTN) in India. The association of depression with socio-demographic profile and clinical risk factors was also assessed. Material and methods. In this cross-sectional epidemiological study, T2DM and/or HTN patients attending outpatient department at tertiary care hospitals and private clinics across 54 cities in India were enrolled. The primary outcome measure was to determine the prevalence of depression in T2DM, HTN and T2DM + HTN patients. Association of depression with patients’ demography, socio-economic status, anxiety, and clinically diagnosed insomnia were also investigated. Results. Of 1829 patients, the prevalence of depression in T2DM, HTN and T2DM+HTN cases were found to be 51.03%, 46.94% and 48.64%, respectively. A higher proportion of patients with uncontrolled T2DM and HTN reported depression (T2DM: 77.64% vs. 22.36%; HTN: 72.49% vs. 27.51%). There was a significant association between anxiety and severity of depression across all indications (p<0.0001). Depression was significantly associated with complications in T2DM (p=0.0001) and comorbidities in T2DM + HTN (p=0.0023) cases. Conclusion. Depression is highly prevalent and has a direct significant association with various socio-demographic variables and anxiety in Indian patients with T2DM and/or HTN.
    Źródło:
    European Journal of Clinical and Experimental Medicine; 2019, 4; 315-325
    2544-2406
    2544-1361
    Pojawia się w:
    European Journal of Clinical and Experimental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The utility of nerve conduction studies in patients with diabetic polyneuropathy
    Autorzy:
    Banach, Marta
    Powiązania:
    https://bibliotekanauki.pl/articles/552713.pdf
    Data publikacji:
    2015
    Wydawca:
    Stowarzyszenie Przyjaciół Medycyny Rodzinnej i Lekarzy Rodzinnych
    Tematy:
    type 2 diabetes mellitus
    nerve conduction studies
    diabetic polyneuropathy
    Źródło:
    Family Medicine & Primary Care Review; 2015, 3; 171-174
    1734-3402
    Pojawia się w:
    Family Medicine & Primary Care Review
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The relationship between anthropometry and ankle-brachial index with blood glucose level in patients with type 2 diabetes mellitus at the Community Health Center in Medan, Indonesia
    Autorzy:
    Rina, Amelia
    Burhan, Burhan Burhan
    Aznan, Lelo
    Powiązania:
    https://bibliotekanauki.pl/articles/552972.pdf
    Data publikacji:
    2018
    Wydawca:
    Stowarzyszenie Przyjaciół Medycyny Rodzinnej i Lekarzy Rodzinnych
    Tematy:
    anthropometry
    ankle-brachial index
    blood glucose
    type 2 diabetes mellitus.
    Źródło:
    Family Medicine & Primary Care Review; 2018, 4; 307-312
    1734-3402
    Pojawia się w:
    Family Medicine & Primary Care Review
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Knowledge on risk factors for type 2 diabetes mellitus among secondary school students
    Autorzy:
    Gora, A.
    Szczepanska, E.
    Janion, K.
    Powiązania:
    https://bibliotekanauki.pl/articles/2087307.pdf
    Data publikacji:
    2020
    Wydawca:
    Narodowy Instytut Zdrowia Publicznego. Państwowy Zakład Higieny
    Tematy:
    knowledge
    high school students
    type 2 diabetes mellitus
    risk factors
    Opis:
    Background. Diabetes is a set of metabolic diseases characterized by hyperglycemia caused by improper action and/ or secretion of insulin. Currently, diabetes is becoming a serious challenge in modern medicine, this disease affects 425 million people, and the forecasts indicate that by 2045 the number of cases will increase to 629 million. Objective. The aim of the study was to evaluate the knowledge about risk factors for type 2 diabetes among secondary school students in the Silesian Province in Poland and to determine whether there are differences between the level of knowledge between girls and boys and between first-, second- and third-grade students. Material and methods. The survey was conducted among 650 high school students. The research tool was the author's questionnaire. The obtained results were developed using Microsoft Excel 2010 and Statistica 13.3 (TIBCO Inc.). Results. The definitions of type 2 diabetes were known to 63.9%. 91.8% of high school students indicated excessive body mass as a risk factor for morbidity, while 18.8% of people indicated the appropriate type of obesity increasing the risk of type 2 diabetes. Most of the students considered abnormal eating habits as an important factor increasing the occurrence of the disease (92.4%). The most numerous group of high school students were people with average level of knowledge (89.6%). Conclusions. The knowledge of high school students about risk factors for type 2 diabetes was varied. The most numerous group were high school students characterised by the average level of knowledge. There were no statistically significant differences between the proportion of correctly provided responses by women and men. There were statistically significant differences between the proportion of correctly provided responses by first-, second- and third-graders. Our research shows that educational activities should be undertaken, especially about modifiable risk factors for type 2 diabetes.
    Źródło:
    Roczniki Państwowego Zakładu Higieny; 2020, 71, 4; 431-443
    0035-7715
    Pojawia się w:
    Roczniki Państwowego Zakładu Higieny
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Age-dependent systemic DNA damage in early Type 2 Diabetes mellitus
    Autorzy:
    Rogulj, Dinko
    El Aklouk, Ismail
    Konjevoda, Paško
    Ljubić, Spomenka
    Pibernik Okanović, Mirjana
    Barbir, Ante
    Luburić, Marijana
    Radman, Maja
    Budinski, Ninoslav
    Vučić Lovrenčić, Marijana
    Powiązania:
    https://bibliotekanauki.pl/articles/1038637.pdf
    Data publikacji:
    2017
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    metabolic syndrome
    type 2 diabetes mellitus
    DNA damage
    urinary 8-OHdG
    Opis:
    Oxidative stress, capable of eliciting damage to various biomolecules including DNA, is a recognized component of diabetes mellitus and its complications. Metabolic syndrome (MetS) is associated with the development of type 2 diabetes mellitus (T2DM), as well as other unfavorable outcomes. The aim of this study was to elucidate the role of oxidative stress in the development of T2DM, by investigating association of oxidative DNA damage with metabolic parameters in subjects with MetS and early T2DM. Selected anthropometric and biochemical parameters of MetS, inflammation and oxidative DNA damage: body mass index (BMI), fatty liver index (FLI), waist circumference (WC), total cholesterol, HDL and LDL-cholesterol, gamma-glutamyl transpeptidase (GGT), uric acid, C-reactive protein (CRP), total leukocyte/neutrophil count, and urinary 8-hidroxy-deoxyguanosine (u-8-OHdG) were assessed in male subjects with MetS and both younger (≤55 years) and older (>55 years) subjects with T2DM of short duration without complications. BMI, FLI, WC, total and LDL-cholesterol and uric acid were higher, while the u-8-OHdG was lower in MetS group, when compared to older T2DM subjects. None of these parameters were different neither between MetS and younger T2DM, nor between two sub-groups of subjects with T2DM. Values of CRP, HDL-cholesterol, triglycerides, GGT, leukocytes and neutrophils were not different between all examined groups of subjects. Higher 8-OHdG in older subjects with T2DM suggests that both aging process and diabetes could contribute to the development of DNA damage. Oxidative DNA damage cannot serve as an universal early marker of T2DM.
    Źródło:
    Acta Biochimica Polonica; 2017, 64, 2; 233-238
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Association between RBMS1 gene rs7593730 and BCAR1 gene rs7202877 and Type 2 diabetes mellitus in the Chinese Han population
    Autorzy:
    Kazakova, Elena
    Chen, Meijun
    Jamaspishvili, Esma
    Lin, Zhang
    Yu, Jingling
    Sun, Lulu
    Qiao, Hong
    Powiązania:
    https://bibliotekanauki.pl/articles/1038363.pdf
    Data publikacji:
    2018
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    type 2 diabetes mellitus
    RBMS1 gene
    BCAR1 gene
    single nucleotide polymorphisms
    SNPscan
    Opis:
    Two recent studies found that RBMS1 gene rs7593730 and BCAR1 gene rs7202877 are related to type 2 diabetes. However, the association of these loci with type 2 diabetes mellitus (T2DM) has not been examined in Chinese. We performed a replication study to investigate the association of the 2 susceptibility loci with T2DM in the Chinese population. We genotyped 1961 Chinese participants (991 with T2DM and 970 controls) for each of the 2 single nucleotide polymorphisms (SNPs) rs7593730 in RBMS1 and rs7202877 near BCAR1 using SNPscan and examined their association with T2DM using logistic regression analysis. We also analyzed the correlation of the SNP alleles and clinical phenotypes. In additive model, genotype association analysis of BCAR1 rs7202877 loci revealed that the homozygous of rs7202877 GG carriers had significantly decreased T2DM risk compared to homozygous carriers of TT (P=0.038, OR 0.44, 95% CI 0.20-0.96). In the recessive model, the GG genotype GG had significantly decreased T2DM risk compared to GT+TT (P=0.043, OR 0.67, 95% CI 0.46-0.99). Allele G was statistically significantly correlated with TC (mmol/L) (P=0.036) and LDL-C (mmol/L) (P=0.007). As for rs7593730, the carriers of CT and TT genotype had significantly decreased T2DM risk compared to the carriers of CC genotype (CT: CC P=0.038, OR 0.71, 95% CI 0.51-0.98; TT: CC P=0.010, OR 0.32, 95% CI 0.13-0.76). In a dominant model, TT+CT: CC (P=0.013, OR 0.673, 95% CI 0.49-0.92) and in a recessive model, TT: CT+CC (P=0.019, OR 0.59, 95% CI 0.39-0.92). The T allele carriers had significantly decreased T2DM risk compared to the carriers of C (P=0.002, OR 0.65, 95% CI 0.50-0.86). Allele T was statistically correlated with FINS (P=0.010). In conclusion, our study showed that RBMS1 gene rs7593730 and BCAR1 gene rs7202877 were significantly associated with type 2 diabetes in the Chinese population.
    Źródło:
    Acta Biochimica Polonica; 2018, 65, 3; 377-382
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Prevalence and Outcomes of Diabetes among COVID-19 Patients in Duhok COVID-19 Health Facilities: a Cross-Sectional Study
    Częstość występowania i wyniki leczenia cukrzycy wśród pacjentów z COVID-19 w placówkach ochrony zdrowia zajmujących się COVID-19 w Duhok: badanie przekrojowe
    Autorzy:
    Hussein, Hozan Qasim
    Salih, Ahmed Mohamed
    Merza, Muayad Aghali
    Powiązania:
    https://bibliotekanauki.pl/articles/2188094.pdf
    Data publikacji:
    2023-03-31
    Wydawca:
    Akademia Bialska Nauk Stosowanych im. Jana Pawła II w Białej Podlaskiej
    Tematy:
    type 2 diabetes mellitus
    outcomes
    COVID-19
    vaccine
    prevalence
    mortality
    cukrzyca typu 2
    wyniki leczenia
    szczepionka
    częstość występowania
    śmiertelność
    Opis:
    Background. The objectives of this study were to determine the prevalence of type 2 diabetes mellitus (T2DM) among patients with COVID-19, examining the relationship between COVID-19 severity and T2DM in hospitalized patients, detecting T2DM outcomes in COVID-19 patients, and identifying the vaccination rates of COVID-19 patients with T2DM. Material and methods. A prospective, cross-sectional study was conducted on Duhok (Iraqi Kurdistan) hospitalized COVID-19 patients. Demographic, clinical, and laboratory characteristics of all confirmed COVID-19 by RT-PCR with coexisting T2DM were collected between early November 2021 and late April 2022. T2DM patients with HbA1c levels ≥7% were considered a poor control group, while those <7% were considered a good control group. Results. Out of 530 hospitalized COVID-19 patients, 158 (29.81%) were T2DM. Among 158 patients, 23 (14.56%) were vaccinated, of whom 17 (10.76%) were fully vaccinated and 6 (3.80%) partially vaccinated. Considering patient outcomes, chronic pulmonary disease (p=0.0106), obesity (p=<0.0001), patients on combined oral antidiabetic and insulin (p=0.0204), and poorly controlled DM (p=<0.0001) were significant predictors of mortality. Conclusions. The prevalence of T2DM in hospitalized COVID-19 patients was relatively high in Duhok. In contrast with the previous studies reported in the literature, the COVID-19 vaccination coverage was unsatisfactory. Therefore, raising awareness concerning health education about the severity and mortality rates of COVID-19 should be mandatory to achieve better disease prognosis.
    Wprowadzenie. Celem niniejszego badania było określenie częstości występowania cukrzycy typu 2 wśród pacjentów z COVID-19, zbadanie związku między nasileniem COVID-19 a cukrzycą typu 2 u pacjentów hospitalizowanych, stwierdzenie wyników leczenia cukrzycy typu 2 u pacjentów z COVID-19 oraz określenie wskaźników szczepienia pacjentów z COVID-19 z cukrzycą typu 2. Materiał i metody. Prospektywnym badaniem przekrojowym objęto pacjentów z COVID-19 hospitalizowanych w Duhok w irackim Kurdystanie. Charakterystyka demograficzna, kliniczna i laboratoryjna wszystkich potwierdzonych metodą RT-PCR przypadków COVID-19 ze współistniejącą cukrzycą typu 2 została zgromadzona między początkiem listopada 2021 a końcem kwietnia 2022. Pacjenci z cukrzycą typu 2 z poziomem HbA1c ≥7% zostali uznani za słabą grupę kontrolną, natomiast pacjenci z <7% za dobrą grupę kontrolną. Wyniki. Spośród 530 hospitalizowanych pacjentów z COVID-19, u 158 (29,81%) występowała cukrzyca typu 2. Wśród 158 pacjentów 23 (14,56%) było zaszczepionych, w tym 17 (10,76%) w pełni, a 6 (3,80%) częściowo. Biorąc pod uwagę wyniki leczenia, przewlekła choroba płuc (p=0,0106), otyłość (p=<0,0001), pacjenci przyjmujący doustne leki przeciwcukrzycowe w skojarzeniu z insuliną (p=0,0204) oraz źle kontrolowane przypadki cukrzycy (p=<0,0001) były istotnymi predyktorami śmiertelności. Wnioski. Częstość występowania cukrzycy typu 2 u pacjentów z COVID-19 hospitalizowanych w Duhok była stosunkowo wysoka. W przeciwieństwie do wcześniejszych danych, współczynniki szczepień przeciwko COVID-19 były niezadowalające. W związku z tym, podnoszenie świadomości w zakresie edukacji zdrowotnej na temat ciężkości i śmiertelności COVID-19 powinno być obowiązkowe w celu uzyskania lepszej prognostyki choroby.
    Źródło:
    Health Problems of Civilization; 2023, 17, 1; 24-35
    2353-6942
    2354-0265
    Pojawia się w:
    Health Problems of Civilization
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    "MitoTea": Geranium robertianum L. decoctions decrease blood glucose levels and improve liver mitochondrial oxidative phosphorylation in diabetic Goto-Kakizaki rats
    Autorzy:
    Ferreira, Fernanda
    Peixoto, Francisco
    Nunes, Elsa
    Sena, Cristina
    Seiça, Raquel
    Santos, Maria
    Powiązania:
    https://bibliotekanauki.pl/articles/1040293.pdf
    Data publikacji:
    2010
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    oxidative phosphorylation
    herbal medicine
    Vaccinium myrtillus L.
    Goto-Kakizaki (GK) rats
    type 2 diabetes mellitus
    Geranium robertianum L.
    Opis:
    Several chemical compounds found in plant products have proven to possess beneficial properties, being currently pointed out due to their pharmacological potential in type 2 diabetes mellitus complications. In this context, we studied the effect of Geranium robertianum L. (herb Robert) leaf decoctions in Goto-Kakizaki (GK) rats, a model of type 2 diabetes. Our results showed that oral administration of G. robertianum leaf decoctions over a period of four weeks lowered the plasma glucose levels in diabetic rats. Furthermore, the treatment with G. robertianum extracts improved liver mitochondrial respiratory parameters (state 3, state 4 and FCCP-stimulated respiration) and increased oxidative phosphorylation efficiency.
    Źródło:
    Acta Biochimica Polonica; 2010, 57, 4; 399-402
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Selected adipokines as potential prognostic and diagnostic agents in treatment of metabolic disorders associated with obesity
    Wybrane adipokiny jako potencjalne czynniki prognostyczne i diagnostyczne w leczeniu zaburzeń metabolicznych towarzyszących otyłości
    Autorzy:
    Stocerz, Klaudia
    Sokal, Arkadiusz
    Kuczera, Mariusz
    Kadela-Tomanek, Monika
    Orlińska, Kinga
    Olczyk, Paweł
    Powiązania:
    https://bibliotekanauki.pl/articles/33294903.pdf
    Data publikacji:
    2024-06-25
    Wydawca:
    Śląski Uniwersytet Medyczny w Katowicach
    Tematy:
    obesity
    type 2 diabetes mellitus
    metabolic disorders
    adipokines
    leptin
    visfatin
    chemerin
    omentin-1
    otyłość
    cukrzyca typu 2
    zaburzenia metaboliczne
    adipokiny
    leptyna
    wisfatyna
    chemeryna
    omentyna-1
    Opis:
    Obesity is a chronic disease that constitutes a global problem and a serious challenge to public health. In the course of this disease, excessive accumulation of fat tissue occurs in the body, which not only leads to an increased risk of health complications, but also negatively affects the quality of life. Fat cells – adipocytes – are responsible for the biosynthesis and release of adipokines, among others, leptin, visfatin, chemerin and omentin-1. They are active biological substances, including mediators of inflammation, which may lead to the development of metabolic disorders in the body. The above-mentioned properties of the described adipokines make it possible to potentially use them as diagnostic and therapeutic factors in the course of obesity and its accompanying disorders such as insulin resistance, type 2 diabetes mellitus, and cardiometabolic complications. Despite significant progress in understanding the role played by the discussed adipokines, further research is necessary to precisely describe the mechanisms of action and to determine the precise relationship between their plasma concentrations and state of diseases.
    Otyłość to przewlekła choroba, stanowiąca globalny problem i poważne wyzwanie dla zdrowia publicznego. W jej przebiegu dochodzi do nadmiernego nagromadzenia się tkanki tłuszczowej w organizmie, co prowadzi nie tylko do wzrostu ryzyka wystąpienia powikłań zdrowotnych, lecz także negatywnie wpływa na jakość życia. Komórki tłuszczowe – adipocyty – są odpowiedzialne za biosyntezę i uwalnianie adipokin, do których należą m.in. leptyna, wisfatyna, chemeryna oraz omentyna-1. Są to aktywne substancje biologiczne, mogące wykazywać właściwości prozapalne lub przeciwzapalne. Zaburzenie równowagi pomiędzy adipokinami prozapalnymi i adipokinami przeciwzapalnymi może prowadzić do rozwoju zaburzeń metabolicznych. Wspomniane właściwości adipokin sprawiają, że możliwe jest ich potencjalne wykorzystanie jako czynników diagnostycznych oraz terapeutycznych w przebiegu otyłości, a także towarzyszących jej zaburzeń, takich jak insulinooporność, cukrzyca typu 2 czy powikłania kardiometaboliczne. Pomimo znacznego postępu w poznaniu roli, jaką odgrywają omówione adipokiny, konieczne są dalsze badania, których wyniki umożliwią precyzyjne omówienie mechanizmów ich działania oraz określą ścisłe zależności ich stężeń w osoczu od stanu choroby.
    Źródło:
    Annales Academiae Medicae Silesiensis; 2024, 78; 138-145
    1734-025X
    Pojawia się w:
    Annales Academiae Medicae Silesiensis
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
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