- Tytuł:
- Mutagenicity induced in Salmonella strains TA98 and TA100 by diphenylthiophenes
- Autorzy:
-
Budzikur, K. A.
Góra, M.
Chachaj, A.
Mielżyńska-Švach, D.
Tejs, S.
Łuczyński, M. K. - Powiązania:
- https://bibliotekanauki.pl/articles/363118.pdf
- Data publikacji:
- 2011
- Wydawca:
- Uniwersytet Warmińsko-Mazurski w Olsztynie
- Tematy:
-
test Amesa
mutacja
monomery tiofenowe
Ames test
mutation
thiophene monomers - Opis:
- Mutagenic properties of four different diphenylthiophenes: 3,4-diphenylthiophene, 3,4-di(4'-methylphenyl)thiophene, 3,4-di(4'-methoxyphenyl)thiophene and 3,4-di(4'-pentoxyphenyl)thiophene were investigated applying the Salmonella test. The research was done on two strains of Salmonella Typhimurium: TA98 and TA100, tested in two variants: with (+S9) and without (-S9) enzymatic activation. Only one compound 3,4-di(4'-methylphenyl)thiophene showed mutagenic activity when studied with metabolic activation (+S9) and its mutagenic rate (MR) score was 3.41 for the dose of 10.00µg*plate-1. Other studied compounds did not show any mutagenic activity (+/-S9) and their MR score did not exceed the threshold value of 2.0.
- Źródło:
-
Environmental Biotechnology; 2011, 7, 2; 65-69
1734-4964 - Pojawia się w:
- Environmental Biotechnology
- Dostawca treści:
- Biblioteka Nauki
Artykuł