- Tytuł:
- A novel approach to computer aided analysis of human serum proteins chromatoelectrophoresis
- Autorzy:
-
Waśko, M.
Orzechowski, P.
Wnuk, N.
Krzych, M. - Powiązania:
- https://bibliotekanauki.pl/articles/333481.pdf
- Data publikacji:
- 2008
- Wydawca:
- Uniwersytet Śląski. Wydział Informatyki i Nauki o Materiałach. Instytut Informatyki. Zakład Systemów Komputerowych
- Tematy:
-
elektroforeza chromatografia
białka surowicy
przełom algorytmów
przetwarzanie obrazu
chromatoelectrophoresis
serum proteins
watershed algorithms
image processing - Opis:
- Chromatoelectrophoresis is a laboratory technique which depicts changes in multiple protein fractions inclusively. The combined, simultaneous analysis based on two key protein features (charge and molecular weight) offers a unique opportunity for better understanding of serum protein composition as well as it indicates the fraction which needs more thorough investigation. Because of those promising features, the chromatoelectrophoresis with automated analysis is expected to be a valuable laboratory test, aiding the process of medical diagnosis. However, without information technology support, analyzing the results of chromatoelectrophoresis would be tedious and time-consuming. For better optimization, both an algorithm for output image analysis and application with user-friendly interface were developed. Planning, development and testing were conducted at AGH University of Science and Technology and Jagiellonian University, Medical College in Cracow, Poland. With this article, we present the results of the first year of cooperation, code-named ChromSee.org project. The algorithm for distinguishing, naming and analyzing the content of fractions, the application and their utility in real-life settings are described, as well as potential future developments.
- Źródło:
-
Journal of Medical Informatics & Technologies; 2008, 12; 129-135
1642-6037 - Pojawia się w:
- Journal of Medical Informatics & Technologies
- Dostawca treści:
- Biblioteka Nauki
Artykuł