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    Wyświetlanie 1-5 z 5
    Tytuł:
    Kinetics of active substance release from flat biopolymer multilayer films
    Autorzy:
    Michalak, Iwona
    Traczyk, Dariusz
    Mucha, Maria
    Powiązania:
    https://bibliotekanauki.pl/articles/1035524.pdf
    Data publikacji:
    2010
    Wydawca:
    Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
    Tematy:
    chitosan
    drug release
    polylactid
    polymer films
    swelling kinetics
    Opis:
    Abstract. Polymer films were made of different biodegradable materials. Solid support of model active substance (salicylic acid) was unmodified and modified (crosslinked with glutaraldehyde) chitosan and outside layers were polylactid acid (PLA). The aim of the study was to obtain the controlled release kinetics of active substance, in medium of pH 5.6 which is similar to conditions occurring on the human skin surface. The chitosan films were investigated with swelling kinetics while multilayer films were studied with release kinetics of active substance (salicylic acid). The amount of salicylic acid released from film was measured using a UV-VIS spectrophotometer. The appropriate mathematical model was also adjusted to the experimental points. The results prove that the swelling process follows the first order kinetics but the results of release process are fitted with Peppas model.
    Źródło:
    Progress on Chemistry and Application of Chitin and its Derivatives; 2010, 15; 107-116
    1896-5644
    Pojawia się w:
    Progress on Chemistry and Application of Chitin and its Derivatives
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    New materials based on hyaluronic acid and egg albumin mixture
    Autorzy:
    Gadomska, Magdalena
    Musiał, Katarzyna
    Sionkowska, Alina
    Powiązania:
    https://bibliotekanauki.pl/articles/1844862.pdf
    Data publikacji:
    2021
    Wydawca:
    Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
    Tematy:
    hyaluronic acid
    albumin from chicken egg
    mechanical properties
    polymer films
    Opis:
    In this work, new materials based on the mixture of hyaluronic acid and albumin from chicken eggs have been studied. Tests were carried out to determine the molecular weight of the tested hyaluronic acids. The properties of hyaluronic acid were investigated and significant differences were found in the mechanical properties of the tested compound, depending on its molecular weight. It was found that egg albumin can be combined with hyaluronic acid and thin films can be obtained. Spectrometric tests were performed both for pure compounds and for mixtures of hyaluronic acid with chicken egg albumin. IR spectroscopy showed that interactions between hyaluronic acid and egg albumin are mainly by hydrogen bonds, as the shifts in the main bands in IR spectra were observed. The addition of egg albumin to hyaluronic acid leads to the decrease of its mechanical properties. The deterioration of the mechanical properties of polymer films from HA-albumin mixtures may be due to interactions between compounds which were shown in the IR spectra. The thin films based on hyaluronic acid and egg albumin blend can be used as adhesive materials in biomedicine and cosmetics. Both biopolymers are biocompatible and biodegradable so we can expect a biocompatible and biodegradable material for potential application as adhesives.
    Źródło:
    Engineering of Biomaterials; 2021, 4, 160; 15-21
    1429-7248
    Pojawia się w:
    Engineering of Biomaterials
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Materials based on chitosan enriched with zinc nanoparticles for potential applications on the skin
    Autorzy:
    Kulka, Karolina
    Szmejkowska, Andżelika
    Sionkowska, Alina
    Wypij, Magdalena
    Golińska, Patrycja
    Powiązania:
    https://bibliotekanauki.pl/articles/27324035.pdf
    Data publikacji:
    2022
    Wydawca:
    Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
    Tematy:
    chitosan
    zinc oxide nanoparticles
    polymer films
    antimicrobial activity
    chitozan
    biomateriały
    biodegradowalność
    Opis:
    Chitosan as a nontoxic, biodegradable, and biocompatible biopolymer with film-forming properties can also be modified to improve its parameters. Modification of polymer films by the addition of nanoparticles is an increasingly common solution due to the higher efficiency of products at the nanoscale compared to the macroscale. In this work, thin chitosan films enriched with biogenic zinc oxide nanoparticles (ZnONPs) from Fusarium solani IOR 825 were obtained by the solvent evaporation method. The influence of nanoadditive on the physicochemical, mechanical, and antimicrobial properties of the polymeric matrix was evaluated. Two different concentrations of ZnONPs were added to the chitosan solution. Spectrometric measurements, mechanical tests, microscopic imaging, and microbiological tests were performed for nanoparticlesmodified and control samples. Analysis revealed that ZnONPs influence the properties of chitosan films. FTIR spectroscopy showed changes that are the result of interactions between polymer matrix and the additive. Modified samples were characterized by increased values of Young’s modulus and tensile strength. SEM analysis combined with energy-dispersive X-ray spectrometry confirmed the presence of zinc in the modified films. The addition of nanoparticles slightly affected the surface morphology of the tested samples, and an increase in roughness was observed. Microbiological tests showed the biostatic activity of the films containing ZnONPs. The obtained films based on chitosan with the addition of ZnONPs can be considered easy-to-obtain biomaterials with potential use as cosmetic and biomedical products.
    Źródło:
    Engineering of Biomaterials; 2022, 25, 167; 24--31
    1429-7248
    Pojawia się w:
    Engineering of Biomaterials
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Characteristic of fish collagen films cross-linked with glutaraldehyde
    Autorzy:
    Kulka-Kamińska, Karolina
    Brudzyńska, Patrycja
    Sionkowska, Alina
    Lewandowska, Katarzyna
    Piwowarski, Łukasz
    Powiązania:
    https://bibliotekanauki.pl/articles/27324037.pdf
    Data publikacji:
    2023
    Wydawca:
    Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
    Tematy:
    collagen
    glutaraldehyde
    cross-linking
    polymer films
    marine sources
    kolagen
    biomateriały
    polimery
    Opis:
    Collagen is a valuable biopolymer in many fields, especially in biomedical sciences. Thanks to its biodegradability and high biocompatibility, it is a desirable material for applications that require contact with the human body. There are many sources of collagen, of which marine-origin collagen has become an important one in recent times. Pure collagen has poor stability and is sensitive to the effects of heat and other external factors. The cross-linking process can improve the properties of collagen materials. Many different methods of cross-linking can be distinguished, including chemical ones. In this study, we were concerned to obtain collagen films modified with glutaraldehyde (GTA). The influence of this additive on the chemical, mechanical, swelling, and hydrophilic properties of the biopolymeric matrix was evaluated. Two different concentrations of collagen were used, as well as three different concentrations of GTA. Results of the analysis showed that the properties of the obtained films were affected by the addition of even a small amount of cross-linker. Spectroscopic measurements indicated minor changes that reflect interactions between GTA and the collagen matrix. Mechanical tests showed changes for modified samples in values of tensile strength, breaking force, and elongation at break. The hydrophilicity decreased slightly for films with GTA. The durability of the modified samples in the swelling test increased. Differences between 1% and 2% collagen films with additives were also observed. The GTA-obtained fish collagen films can be promising materials for biomedical applications.
    Źródło:
    Engineering of Biomaterials; 2023, 26, 168; 25--32
    1429-7248
    Pojawia się w:
    Engineering of Biomaterials
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Wielowarstwowe filmy polimerowe otrzymywane metodą LbL - warstwa po warstwie (ang. layer-bylayer) : rozwój i zastosowanie
    Multilayered polymer films obtained by means of layer-by-layer (LbL) method : evolution and applications
    Autorzy:
    Wójcik, A.J.
    Powiązania:
    https://bibliotekanauki.pl/articles/171608.pdf
    Data publikacji:
    2014
    Wydawca:
    Polskie Towarzystwo Chemiczne
    Tematy:
    metoda LbL
    warstwa po warstwie
    filmy polimerowe
    polielektrolity
    LbL
    layer-by-layer
    polymer films
    polyelectrolytes
    Opis:
    The production of varied materials with nanoscale precision requires both suitable components and a right method. In the past two decades, layer-by-layer (LbL) assembly has been proven to be a convenient and versatile technique for fabrication of functional films. The LbL method enables obtaining systems composed of a few or even hundreds layers of beforehand chosen substances, which are characterized by a thickness ranging from nano- to micrometers. The building blocks of LbL assembly include, but are not limited to, synthetic polymers, polymeric microgels, biomacromolecules, (nano)particles, dendritic molecules, and complexes of these species [1]. This method involves simple alternative adsorption of oppositely charged polyelectrolytes on supporting materials [2]. The LbL assembly can be driven by multiple weak interactions, including electrostatic interactions, hydrogen-bonds, halogen-bonds, coordination bonds, charge-transfer interactions, biospecific interactions (e.g., sugar–lectin interactions), cation–dipole interactions, and the combined interaction of the above forces, etc. The multilayered composite films fabricated by means of the LbL technique have generated much interest among researchers worldwide due to the simplicity of the whole process by which they are produced and their numerous applications such as antireflection coatings, superhydrophobic surfaces, electrochromic devices, biosensors, cell adhesion or resistance coatings, drug delivery systems, proton exchange membranes, solar-energy conversion devices, and separation membranes [3]. In this review the evolution of the LbL method and the applications of the multilayered polymer films were discussed.
    Źródło:
    Wiadomości Chemiczne; 2014, 68, 9-10; 897-918
    0043-5104
    2300-0295
    Pojawia się w:
    Wiadomości Chemiczne
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-5 z 5

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