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Wyświetlanie 1-13 z 13
Tytuł:
Ospa małpia potencjalnym zagrożeniem
Monkeypox – a potential zoonotic threat
Autorzy:
Gliński, Zdzisław
Żmuda, Andrzej
Powiązania:
https://bibliotekanauki.pl/articles/22403346.pdf
Data publikacji:
2022
Wydawca:
Krajowa Izba Lekarsko-Weterynaryjna
Tematy:
ospa malpia
epidemiologia
charakterystyka
patogeneza
rozpoznanie
człowiek
zagrożenia zdrowia
choroby odzwierzęce
wirus ospy małpiej
wrota zakażenia
drogi zakażenia
monkeypox
smallpox
pathology
control
Opis:
Monkeypox is an emerging zoonotic disease and a potential biological weapon. It is caused by enveloped, complex, double-stranded DNA Orthopoxvirus (Poxviridae), closely related to smallpox virus. Since 1958 monkeypox has been reported in people in several central and western African countries, USA and Europe. Transmission of monkeypox virus (MPV), occurs when a person comes into close contact with skin lesions, body fluids, respiratory droplets from infected animal or human, or with contaminated fomites. Monkeypox is a communicable disease in nonhuman primates, wild rodents and prairie dogs. Clinical symptoms in prairie dogs and hon-human primates include cough, history of fever, conjunctivitis, lack of appetite, respiratory signs and rash. In humans, the disease begins with fever, headache, muscle aches, and exhaustion. The patient develops a rash progressing to macules, papules, vesicles, pustules and scabs, often resembling chickenpox. In monkeypox human cases lymphadenopathy is prominent distinguishing this disease from smallpox, already eradicated worldwide. In the African epidemics, 90% of the patients were children below 15 years of age. Monkeypox can be diagnosed with molecular methods (RT-PCR, pan-orthopox PCR), immunohistochemistry, isolation of MPV in cell culture, ELISA and or electron microscopy. To treat patients and to control monkeypox outbreak, the smallpox vaccine, antivirals drugs, and vaccinia immune globulin (VIG) can be used. Monkeypox is a disease of global public health importance and in this article major issues related to this emerging zoonosis are presented.
Źródło:
Życie Weterynaryjne; 2022, 97, 07; 433-437
0137-6810
Pojawia się w:
Życie Weterynaryjne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Afrykański pomór koni
African horse sickness
Autorzy:
Gliński, Zdzisław
Żmuda, Andrzej
Powiązania:
https://bibliotekanauki.pl/articles/22392763.pdf
Data publikacji:
2022
Wydawca:
Krajowa Izba Lekarsko-Weterynaryjna
Tematy:
konie
epidemiologia
etiologia
patogeneza
objawy kliniczne
zmiany anatomopatologiczne
rozpoznanie
profilaktyka
choroby zwierząt
afrykański pomór koni
postępowanie ze zwierzętami
African horse sickness clinical cases
diagnosis
prophylaxis
Opis:
African horse sickness is a highly infectious and devastating disease that causes great suffering and many fatalities in equids. It commonly affects horses, mules, donkeys and dogs. The disease is caused by nine different serotypes of the African horse sickness virus, ASHV, genus Orbivirus (Reoviridae), and it is spread mainly by hematophagous arthropods of the Culicoides. Some crossreactions are observed between 1 and 2,3 and 7,5 and 8, and 6 and 9 serotypes. Clinical forms of AHS include peracute pulmonary, subacute cardiac, and mixed as well as subclinical (horse sickness fever). The most severe, with mortality rates exceeding 95%, is the pulmonary form, accompanied by fever, mild depression, sweating, spasmodic coughing, anorexia and respiratory distress. The subacute cardiac form with a mortality of about 50%, is characterized by fever, swelling of the head, neck and supraorbital fossae and sometimes, petechial hemorrhages in the eyes. The mildest form of the disease is generally not fatal and is accompanied by a low grade fever, anorexia, depression and congestion of the mucous membranes. The most common cases with a 70% mortality rate, are mixture of the pulmonary and cardiac forms. Differential diagnosis include equine encephalosis virus (also Orbivirus), equine infectious anemia, equine viral arteritis, anaplasmosis, babesiosis, or theileriosis. Clinical AHS cases have also been described in dogs, with acute respiratory distress syndrome or sudden death. Diagnosis of the disease is based on typical clinical signs and lesions, a history consistent with vector transmission and confirmation by laboratory detection of virus and/or anti-virus antibodies. Currently, prevention and control of African horse sickness is based on administration of live attenuated vaccines and control of the arthropod vectors.
Źródło:
Życie Weterynaryjne; 2022, 97, 06; 385-389
0137-6810
Pojawia się w:
Życie Weterynaryjne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Enzootyczne ronienie owiec
Enzootic abortion in sheep
Autorzy:
Gliński, Zdzisław
Żmuda, Andrzej
Powiązania:
https://bibliotekanauki.pl/articles/22416175.pdf
Data publikacji:
2022
Wydawca:
Krajowa Izba Lekarsko-Weterynaryjna
Tematy:
owce
zaburzenia rozrodu
enzootyczne ronienie owiec
Chlamydophila abortus
epidemiologia
etiologia
patogeneza
zmiany anatomopatologiczne
objawy kliniczne
rozpoznanie
rozród zwierząt
postępowanie ze zwierzętami
enzootic abortion
ewes
pregnancy
vaccines
Źródło:
Życie Weterynaryjne; 2022, 97, 08; 533-537
0137-6810
Pojawia się w:
Życie Weterynaryjne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Koronawirusy i koronawirozy człowieka i zwierząt
Humans and animals coronaviruses and coronaviroses
Autorzy:
Gliński, Zdzisław
Żmuda, Andrzej
Powiązania:
https://bibliotekanauki.pl/articles/22018917.pdf
Data publikacji:
2020
Wydawca:
Krajowa Izba Lekarsko-Weterynaryjna
Tematy:
wirusologia
koronawirusy
Coronaviridae
koronawirozy
patogeneza
koronawirusy ludzkie
objawy chorobowe
czynniki chorobotwórcze
choroby człowieka
choroby zwierząt
koronawirusy zwierzęce
coronaviruses
human and animal coronaviroses
Opis:
Coronaviruses cause a large variety of diseases in humans, livestock, companion and also in wild animals. Three times in the 21st century, coronavirus outbreaks (SARS, MERS and COVID-19), have emerged from animal reservoirs to cause severe diseases in humans and global transmission concerns. There are hundreds of coronaviruses, most of which circulate among animals including pigs, cattle, ferrets, rabbits, camels, bats, cats and dogs. Transmissible gastroenteritis virus (TGE-CoV), and porcine epidemic diarrhea virus (PED-CoV), cause severe gastroenteritis in young piglets, leading to significant morbidity, mortality, and ultimately economic losses. Bovine CoV, Rat CoV, and infectious bronchitis virus (IBV), cause mild to severe infections in cattle, rats, and chickens, respectively. Feline coronavirus enteritis causes a mild or asymptomatic infection in domestic cats, but feline infectious peritonitis coronavirus (FIP-CoV), causes a lethal disease in the domestic cat, and other members of the Felidae family. Sometimes, animal coronaviruses evolve to infect a new host species and spread in that new host, animal or human, causing disease. This host jump or cross-species transmission may lead to serious consequences for a new host population. This review focuses on the etiology, epidemiology, disease mechanisms and pathogenesis as well as bioasecurity and immunoprophylaxis against coronaviral infections.
Źródło:
Życie Weterynaryjne; 2020, 95, 06; 335-346
0137-6810
Pojawia się w:
Życie Weterynaryjne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Beztlenowcowa enterotoksemia owiec
Pulpy kidney disease
Autorzy:
Gliński, Zdzisław
Żmuda, Andrzej
Powiązania:
https://bibliotekanauki.pl/articles/22180967.pdf
Data publikacji:
2021
Wydawca:
Krajowa Izba Lekarsko-Weterynaryjna
Tematy:
owce
enterotoksemia beztlenowcowa
epidemiologia
Clostridium perfringens typ D
patogeneza
objawy kliniczne
nerki
autoliza
rozpoznanie
profilaktyka
szczepienia ochronne
choroby zwierząt
zmiany pośmiertne
narządy wewnętrzne
postępowanie ze zwierzętami
Clostridium perfringens type D
sheep
pulpy kidney
vaccination
Opis:
This article aims at presentation of disease in sheep that follows upset in gut microbiota, due to sudden changes to a rich diet. Enterotoxemia (pulpy kidney disease), most commonly occurs in rapidly growing or weaned lambs, when there is a rapid shift to a low fiber and high carbohydrate diet. The disease develops when Clostridium perfringens type D, that normally inhabits the animal intestines, begins to multiply fast and produces an epsilon toxin that results in toxemia and frequently, the sudden death. Rapid multiplication of type D and epsilon toxin production is favored by excess of dietary starch in the small intestine. C. perfringens type D can also cause a chronic form of the disease – focal, symmetrical encephalomalacia. Diagnosis is based on clinical signs, history of sudden death cases in herd and confirmation by necropsy, brain histopathology, bacteriological examination, RT-PCR and ELISA. Treatment, prevention and control of pulpy kidney disease depends on serotherapy with antitoxin, supportive treatment and correction of diet and vaccination. Effective vaccines are commercially available. All animals in the herd, especially the young ones, should be vaccinated to minimize the risk of enterotoxemia in sheep.
Źródło:
Życie Weterynaryjne; 2021, 96, 06; 412-414
0137-6810
Pojawia się w:
Życie Weterynaryjne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Wirus Nipah - zagrożenie dla hodowli, zoonoza, broń biologiczna
Nipah virus - threat to animal breeding, zoonosis, biological weapon
Autorzy:
Gliński, Zdzisław
Żmuda, Andrzej
Powiązania:
https://bibliotekanauki.pl/articles/21978141.pdf
Data publikacji:
2020
Wydawca:
Krajowa Izba Lekarsko-Weterynaryjna
Tematy:
wirus Nipah
choroba Nipah
epidemiologia
etiologia
patogeneza
zoonozy
choroby zwierząt
transmisja wirusów
broń biologiczna
choroby człowieka
Nipah virus
humans
pigs
zoonosis
biological weapon
Opis:
This article aims at presenting Nipah virus (NiV), which is becoming a serious threat for animal breeding, as a zoonotic agent and as a potential biological weapon. Nipah virus is a paramyxovirus, genus Henipavirus, whose reservoir host are is fruit bats of the genus Pteropus. The virus can cause severe respiratory disease in resulting in significant economic losses, and also in other animals: horses, cattle, and in cats and dogs. Clinical signs in pigs vary, depending on the age and the individual response to the virus. In general, mortality is low, except in piglets. however, morbidity is high in all age groups. If an outbreak is suspected, the animal premises should be quarantined immediately. Culling of animals with respiratory signs and the close supervision of burial or incineration of carcasses may be necessary to reduce the risk of NiV transmission to people. Restricting or banning the movement of animals from infected farms to other areas can reduce the spread of the disease. The Nipah virus can be transmitted to humans from bats or pigs or from contaminated foods. It can also be transmitted directly between humans. Resulting severe illness is characterized by encephalitis and/or respiratory disease and fatality rate is estimated at 40% to 75%. There is one vaccine available for both people and animals. The NiV to be considered as potential agent of bioterrorism.
Źródło:
Życie Weterynaryjne; 2020, 95, 02; 69-73
0137-6810
Pojawia się w:
Życie Weterynaryjne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Choroba bornaska - tajemnicza choroba
Borna disease - a mysterious disease
Autorzy:
Gliński, Zdzisław
Żmuda, Andrzej
Powiązania:
https://bibliotekanauki.pl/articles/22181052.pdf
Data publikacji:
2021
Wydawca:
Krajowa Izba Lekarsko-Weterynaryjna
Tematy:
konie
owce
koty
psy
choroby wirusowe
choroba Borna
etiologia
wirus choroby Borna
patogeneza
immunopatologia
objawy kliniczne
zaburzenia neurologiczne
diagnostyka
profilaktyka
bydło
choroby zwierząt
właściwości
postępowanie ze zwierzętami
Borna disease
immunopathology
diagnosis
neurologic disorders
Opis:
Borna disease virus (BoDV, Orthobornavirus; Bornaviridae), is the causative agent of Borna disease, mostly lethal polioencephalomyelitis that affects primarily horse and sheep but also and other mammals. It is ssRNA virus, that replicates within the nucleus of target cells, at first at the entry site, than it migrates intraaxonally towards the brain, cerebellum and medulla oblongata. The infection of the central nervous system results in severe neurological disorder that is caused primarily by the hosts cell-mediated immunopathological reactions. The clinical manifestations of the bornaviral diseases are highly variable. Thus, in addition to acute, lethal encephalitis, they can cause persistent neurologic disease associated with diverse behavioral changes. They also cause a severe retinitis resulting in blindness. The zoonotic potential of the virus has been a matter of an unresolved scientific dispute for decades. The impact of BDV on mental health still remains controversial. BoDV‑1 can induce encephalitis cases, establishing the infection as a potentially lethal zoonosis which can impact both immunocompromised and healthy individuals. Diagnosis can be made serologically (ELISA, IF, Western blot), but detection of antigen markers in peripheral white blood cells (ELISA, FACS) and/or in the brain combined with nucleic acid amplification (nested RT-PCR), is more profitable.
Źródło:
Życie Weterynaryjne; 2021, 96, 12; 820-824
0137-6810
Pojawia się w:
Życie Weterynaryjne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Bokawirusy - nowe parwowirusy chorobotwórcze dla ludzi i psów
Bocaviruses - new parvoviruses pathogenic for humans and dogs
Autorzy:
Gliński, Zdzisław
Żmuda, Andrzej
Powiązania:
https://bibliotekanauki.pl/articles/22030417.pdf
Data publikacji:
2020
Wydawca:
Krajowa Izba Lekarsko-Weterynaryjna
Tematy:
wirusologia
parwowirusy
bokawirusy
epidemiologia
patogeneza
objawy chorobowe
zmiany anatomopatologiczne
rozpoznanie
charakterystyka
bokaparwowirusy psów
choroby zwierząt
bokawirus człowieka
chorobotwórczość
canine bocaparvovirus
CaBoV1–3
human bocavirus
HBoV1
animal bocaviruses
Opis:
This review aims at presentation of a group of parvoviruses, that gain the significance in small animals. Bocaparvovirus 1 (CaBoV1, minute virus of canines), was identified in 1967. Majority of CaBoV1 infections in dogs appear to be subclinical. However, there are also studies, confirming that CaBoV1 is dangerous, especially for developing fetuses, for young puppies and for elderly dogs. Canine Bocaparvovirus 2 (CaBoV2), was identified in 2012 in a litter of puppies, in association with respiratory signs resulting from interstitial pneumonia and with massive enteritis with atrophied and fused villi, severe crypts regeneration, and severe bone marrow and lymphoid atrophy. A third canine bocaparvovirus (CaBoV3), was identified in the liver of a dog with circovirus coinfection. In 2005, the human bocavirus (HBoV), has been isolated from respiratory tract and has been reported worldwide with frequencies ranging from 1.5 to 18.3% in samples from children with upper respiratory tract infections. Three more enteric, human bocaviruses (HBoV2–4), have been found in stool samples. HBoV infections are significantly more frequent in children from 6 month to 3 year of age. So far, no HBoV-specific clinical symptoms are known. Bocaparvoviruses were also isolated from other animal species, including pigs, cats, gorilla, sea lions, rodents and bats.
Źródło:
Życie Weterynaryjne; 2020, 95, 08
0137-6810
Pojawia się w:
Życie Weterynaryjne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Czy wirus Lassa będzie najgroźniejszym zoonotycznym patogenem?
Will Lassa virus become the most fearsome zoonotic pathogen?
Autorzy:
Gliński, Zdzisław
Żmuda, Andrzej
Powiązania:
https://bibliotekanauki.pl/articles/22339828.pdf
Data publikacji:
2022
Wydawca:
Krajowa Izba Lekarsko-Weterynaryjna
Tematy:
objawy chorobowe
patogeneza
wirus Lassa
epidemiologia
zmiany anatomopatologiczne
zmiany histopatologiczne
rozpoznanie
leczenie
profilaktyka
znaczenie zoonotyczne
gorączka Lassa
czynniki chorobotwórcze
źródła zakażenia
drogi zakażenia
symptoms
pathogenesis
control
Lassa fever
Opis:
Lassa virus (Arenaviridae), is the etiological agent of Lassa fever, a severe human disease with high mortality rates for hospitalized patients. Lassa fever can be difficult to distinguish clinically from other viral hemorrhagic fevers. The virus is initially spread to people via contact with urine or feces of an infected multimammate mouse and rat, that remain carriers for life. Once infected, people may transmit Lassa virus in both community and health care settings, by contaminated medical equipment and direct contact with bodily secretions. About 15–20% of hospitalized people with Lassa fever will die from the illness. However, many infected people do not develop symptoms, which typically include fever, headache, vomiting and muscles pain. The main feature of fatal illness is impaired or severely delayed cell mediated immunity leading to fulminant viremia. Early recognition and initiation of targeted care increase patients surviving rates. Lassa fever is diagnosed by ELISA, which may detect IgM and IgG antibodies as well as Lassa virus antigen and RT-PCR used in the early stage of disease. There is currently no licensed vaccine against Lassa fever, and the only treatment available is based on ribavirin. In this article epidemiological aspects as well as diagnostics approaches are presented and discussed in the context of possibly increasing the public health threat with Lassa fever in European countries.
Źródło:
Życie Weterynaryjne; 2022, 97, 04; 245-249
0137-6810
Pojawia się w:
Życie Weterynaryjne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Choroba guzowatej skóry bydła
Lumpy skin disease
Autorzy:
Gliński, Zdzisław
Żmuda, Andrzej
Powiązania:
https://bibliotekanauki.pl/articles/22373052.pdf
Data publikacji:
2022
Wydawca:
Krajowa Izba Lekarsko-Weterynaryjna
Tematy:
choroby wirusowe
etiologia
owady
stawonogi
patogeneza
objawy kliniczne
rozpoznanie
zmiany anatomopatologiczne
zmiany histopatologiczne
profilaktyka
szczepienia ochronne
bydło
występowanie
wektory wirusów
choroba guzowatej skóry bydła
źródła zakażenia
postępowanie ze zwierzętami
diagnostyka różnicowa
lumpy skin disease
clinic
arthropod vectors
vaccination
Opis:
This review aims to summarize the latest development in the epidemiology, pathology, clinic and control of lumpy skin disease (LSD), with the focus on its transboundary spread, possible emergence and economic implications for on cattle production. This notifiable disease is endemic in African and Middle East countries but has started spreading to Asia and south-east Europe, affecting Greece and Bulgaria and countries in the Balkans. Lumpy skin disease is mainly transmitted to infection-free areas by transport of infected animals and by virus vectors, as blood-feeding insects, such as certain species of flies and mosquitoes, or ticks. There is also growing importance of the spread of wildlife, the potential reservoirs of the disease. Generally, fever, anorexia, hypersalivation, lacrimation and characteristic eruptions with painful nodules within the skin, on the muzzle and within the nasal and buccal mucous membranes, on the udder, on genital and rectal mucous membranes. The severe drop in milk production, also abortions, infertility and sometimes death are the clinical manifestations of the disease in a herd. Although the mortality rate is usually less than 10%, the disease morbidity rate can be as high as 100%. The economic significance of LSD is of great concern, given that it threatens international trade and could be used as bioterrorism weapon. Vaccination, strict quarantine measures, limited movement of livestock along with vectors control could be effective for preventing the spread of the disease. Homologous vaccines are more effective than sheeppox virus strain vaccines.
Źródło:
Życie Weterynaryjne; 2022, 97, 05; 315-319
0137-6810
Pojawia się w:
Życie Weterynaryjne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Udział grzybów z rodzaju Malassezia w chorobach ludzi i zwierząt
Malassezia spp. yeasts in human and animal diseases
Autorzy:
Gliński, Zdzisław
Żmuda, Andrzej
Powiązania:
https://bibliotekanauki.pl/articles/22026350.pdf
Data publikacji:
2020
Wydawca:
Krajowa Izba Lekarsko-Weterynaryjna
Tematy:
czynniki chorobotworcze
grzyby
Malassezia
chorobotworczosc
czynniki ryzyka
patogeneza
zmiany anatomopatologiczne
zmiany histopatologiczne
diagnostyka
profilaktyka
leczenie
choroby człowieka
choroby zwierząt
czynniki chorobotwórcze
objawy zakażenia
epidemiology
risk factors
pathogenesis
clinical manifestations
treatment
Opis:
There are many factors involved in the emergence of new infectious diseases or the re-emergence of “old” infectious diseases. Some, result from natural processes such as the evolution of pathogens over time, but many are a result of climate changes, environment pollution, antimicrobial medications and immunosuppression. Lipophilic yeasts Malassezia are associated with diseases affecting animal and human skin. They may also aggravate cutaneous disorders, such as seborrheic dermatitis or exacerbate the course of psoriasis and atopic dermatitis. Due to their specific cell structure, yeasts may be resistant to environmental stress and difficult to eliminate by the host’s immune system. This article outlines the epidemiology, risk factors, pathogenesis, clinical manifestations, and treatment of various human and animals skin infections related to the Malassezia species.
Źródło:
Życie Weterynaryjne; 2020, 95, 07; 414-419
0137-6810
Pojawia się w:
Życie Weterynaryjne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Zakażenie Clostridioides difficile jako zoonoza i antroponoza
Clostridioides difficile infection - zoonosis and reverse zoonosis
Autorzy:
Gliński, Zdzisław
Żmuda, Andrzej
Powiązania:
https://bibliotekanauki.pl/articles/22181032.pdf
Data publikacji:
2021
Wydawca:
Krajowa Izba Lekarsko-Weterynaryjna
Tematy:
konie
trzoda chlewna
psy
koty
bydlo
zoonozy
antropozoonoza
Clostridioides difficile zob.Clostridium difficile
Clostridium difficile
patogeneza
zmiany anatomopatologiczne
czynniki ryzyka
choroby człowieka
bydło
choroby zwierząt
rzekomobłoniaste zapalenie jelit
zapalenie okrężnicy
czynniki chorobotwórcze
właściwości
Clostridioides difficile
zoonosis
antroponosis
Opis:
Clostridioides (Clostridium) difficile is the most common cause of antibiotic and hospital associated diarrhea and severe colitis in humans and also in dogs, cats, horses, cattle and pigs. It appears to be an emerging zoonotic and reversely zoonotic pathogen The primary virulence factors of C. difficile are the two major toxins, toxin A (TcdA) and toxin B (TcdB). Some strains of C. difficile may also produce an ADP-ribosylating binary toxin (CDT). Dogs and cats in animal shelters are a reservoir of human pathogenic C. difficile. Small animals can potentially act as vectors for the transmission of the organism to humans via direct contact or indirect transmission through raw food, or through contaminated water. Inversely, toxin producing ribotypes 014, 027 and 078 of C. difficile can be transmitted from humans to animals. Our article aims at the presentation of this emerging animal associated disease, its pathogenesis, and methods of control.
Źródło:
Życie Weterynaryjne; 2021, 96, 11; 755-760
0137-6810
Pojawia się w:
Życie Weterynaryjne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Choroba maedi-visna nadal problemem w hodowli owiec
Maedi-visna disease, continuous problem in sheep farming
Autorzy:
Gliński, Zdzisław
Żmuda, Andrzej
Powiązania:
https://bibliotekanauki.pl/articles/22443120.pdf
Data publikacji:
2022
Wydawca:
Krajowa Izba Lekarsko-Weterynaryjna
Tematy:
owce
choroba maedi-visna
epidemiologia
etiologia
wirus maedi-visna
patogeneza
czynniki ryzyka
objawy kliniczne
zmiany anatomopatologiczne
zmiany histopatologiczne
diagnostyka
choroby zwierząt
źródła zakażenia
drogi zakażenia
zwalczanie chorób zwierząt
kontrola chorób
maedi-visna
control
serology
sheep
epidemiology
Opis:
Maedi-visna is a multi-systemic disease of sheep caused by a non-oncogenic, exogenous retrovirus of the Lentiviridae subfamily. It is mainly transmitted through the ingestion of milk from infected sheep, although disease can be spread within flocks through direct contact and transmission can occur also in utero. Maedi usually begins insidiously and leads to a classical interstitial pneumonia. On postmortem examination, the lungs may be 2-4 times heavier than normal, due to decreased elasticity and fibrosis. Regional lymph nodes are enlarged with formation of lymphoid follicles with active germinal centers. Visna - the neurological form of the disease, is characterized by chronic and active meningoencephalomyelitis and chorioiditis with massive infiltrations of mononuclear cells around the blood vessels, microglial nodules formation and astrogliosis. Virus isolation is very specific but of variable sensitivity. The cytopathic effects are characteristic, consisting of the appearance of stellate cells and syncytia. The diagnostic methods currently used are based on the detection of either antibodies or the viral genome. The three most commonly tests used, are the PCR and RT-PCR, agar gel immunodiffusion test (AGID) and the enzyme-linked immunosorbent assay (ELISA). Western blot analysis and radio-immunoprecipitation are also performed, but only in specialized laboratories. No commercial vaccines are available to control infection, and to date, monitoring programs have proved to be the only effective tool in controlling this disease.
Źródło:
Życie Weterynaryjne; 2022, 97, 09; 587-591
0137-6810
Pojawia się w:
Życie Weterynaryjne
Dostawca treści:
Biblioteka Nauki
Artykuł
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