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    Wyświetlanie 1-8 z 8
    Tytuł:
    Molekularne mechanizmy lekoopornosci pasozytow
    Autorzy:
    Majewska, A C
    Powiązania:
    https://bibliotekanauki.pl/articles/839311.pdf
    Data publikacji:
    1998
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Tematy:
    lekoopornosc
    parazytologia
    mechanizmy molekularne
    pasozyty
    Opis:
    In spite of the enormous achievements of medical and biological sciences, parasites still constitute important medical and veterinary problem. One of the main obstacles in the treatment and eradication of human and animals parasitic diseases is drug resistance of parasites. This phenomenon has more and more frequently been described both in medical and veterinary practice. The application of numerous molecular biology techniques in modern parasitological laboratories have enabled the investigations of parasites at the DNA level. The results of these studies have revolutionised our knowledge and made possible the recognition of not only the reasons and extent of genetic differentiation of parasites but also the recognition of genetic and molecular mechamisms of drug resistance. The results of many studies showed interspecific, interpopulational, and even intrapopulational heterogeneity of parasites in their sensitivity to antiparasitic drugs. Moreover, it has been found that in various parasites there often exist different molecular bases of the drug resistance. The review concerns different molecular mechanisms of drug resistance in selected parasite taxa (Schistosoma spp., Haemonchus contortus, Leishmania spp., Plasmodium falciparum, Entamoeba histolytica).
    Źródło:
    Annals of Parasitology; 1998, 44, 2; 139-150
    0043-5163
    Pojawia się w:
    Annals of Parasitology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Molekularne mechanizmy lekooporności pasożytów
    Autorzy:
    Majewska, A. C.
    Powiązania:
    https://bibliotekanauki.pl/articles/2148863.pdf
    Data publikacji:
    1998
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Tematy:
    lekoopornosc
    parazytologia
    mechanizmy molekularne
    pasozyty
    Opis:
    In spite of the enormous achievements of medical and biological sciences, parasites still constitute important medical and veterinary problem. One of the main obstacles in the treatment and eradication of human and animals parasitic diseases is drug resistance of parasites. This phenomenon has more and more frequently been described both in medical and veterinary practice. The application of numerous molecular biology techniques in modern parasitological laboratories have enabled the investigations of parasites at the DNA level. The results of these studies have revolutionised our knowledge and made possible the recognition of not only the reasons and extent of genetic differentiation of parasites but also the recognition of genetic and molecular mechamisms of drug resistance. The results of many studies showed interspecific, interpopulational, and even intrapopulational heterogeneity of parasites in their sensitivity to antiparasitic drugs. Moreover, it has been found that in various parasites there often exist different molecular bases of the drug resistance. The review concerns different molecular mechanisms of drug resistance in selected parasite taxa (Schistosoma spp., Haemonchus contortus, Leishmania spp., Plasmodium falciparum, Entamoeba histolytica).
    Źródło:
    Wiadomości Parazytologiczne; 1998, 44, 2; 139-150
    0043-5163
    Pojawia się w:
    Wiadomości Parazytologiczne
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Wodnopochodne epidemie Giardia
    Autorzy:
    Majewska, A C
    Kasprzak, W.
    Powiązania:
    https://bibliotekanauki.pl/articles/841170.pdf
    Data publikacji:
    1995
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Tematy:
    lamblia
    Giardia
    epidemie
    parazytologia
    pasozyty
    epidemiologia
    Opis:
    The authors present the actual informations on waterborne outbreaks of giardiosis as well as the evidences of Giardia cyst transmission by municipal water supply. In the article a recommendation is given to molecular biology techniques which contributed to the armentarium applied in the modern diagnostics of giardiosis.
    Źródło:
    Annals of Parasitology; 1995, 41, 1; 25-31
    0043-5163
    Pojawia się w:
    Annals of Parasitology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Wirusy pasożytniczych pierwotniaków
    VIRUSES OF PARASITIC PROTOZOA
    Autorzy:
    Kasprzak, W.
    Majewska, A. C.
    Powiązania:
    https://bibliotekanauki.pl/articles/2149109.pdf
    Data publikacji:
    1995
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Tematy:
    wirusy
    pierwotniaki
    parazytologia
    pasozyty
    Opis:
    The authors present the actual review on several publications concerning the molecular characterizations of the viruses found in parasitic protozoa such as Giardia, Trichomonas, Leishmania and Entamoeba histolytica. All of the RNA viruses observed in parasitic protozoa showed several similarities and did not considerably differ from the viruses found in simple eukaryotic cells; they closely correspond to dsRNA viruses of yeast. The supposition that the protozoan symbionts detected in laboratories transfer to their hosts in natural conditions seemed to be rational, though, there are no evidences that these symbionts are potential pathogens. However, the opinion reiterates that intestinal protozoa (e.g. Entamoeba histolytica) may serve as vectors for HIV or cofactors of HIV infection. The authors point out that irrespective of the potential role of viruses as vectors in the transfection system for parasitic protozoa, the observed viral system constitutes an unusual experimental system to solve the problems of gene expression.
    Źródło:
    Wiadomości Parazytologiczne; 1995, 41, 2; 131-137
    0043-5163
    Pojawia się w:
    Wiadomości Parazytologiczne
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Wirusy pasozytniczych pierwotniakow
    Autorzy:
    Kasprzak, W
    Majewska, A.C.
    Powiązania:
    https://bibliotekanauki.pl/articles/838835.pdf
    Data publikacji:
    1995
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Tematy:
    wirusy
    pierwotniaki
    parazytologia
    pasozyty
    Opis:
    The authors present the actual review on several publications concerning the molecular characterizations of the viruses found in parasitic protozoa such as Giardia, Trichomonas, Leishmania and Entamoeba histolytica. All of the RNA viruses observed in parasitic protozoa showed several similarities and did not considerably differ from the viruses found in simple eukaryotic cells; they closely correspond to dsRNA viruses of yeast. The supposition that the protozoan symbionts detected in laboratories transfer to their hosts in natural conditions seemed to be rational, though, there are no evidences that these symbionts are potential pathogens. However, the opinion reiterates that intestinal protozoa (e.g. Entamoeba histolytica) may serve as vectors for HIV or cofactors of HIV infection. The authors point out that irrespective of the potential role of viruses as vectors in the transfection system for parasitic protozoa, the observed viral system constitutes an unusual experimental system to solve the problems of gene expression.
    Źródło:
    Annals of Parasitology; 1995, 41, 2; 131-137
    0043-5163
    Pojawia się w:
    Annals of Parasitology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Wodnopochodne epidemie Giardia
    WATERBORNE OUTBREAKS OF GIARDIA
    Autorzy:
    Majewska, A. C.
    Kasprzak, W.
    Powiązania:
    https://bibliotekanauki.pl/articles/2151382.pdf
    Data publikacji:
    1995
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Tematy:
    lamblia
    Giardia
    epidemie
    parazytologia
    pasozyty
    epidemiologia
    Opis:
    The authors present the actual informations on waterborne outbreaks of giardiosis as well as the evidences of Giardia cyst transmission by municipal water supply. In the article a recommendation is given to molecular biology techniques which contributed to the armentarium applied in the modern diagnostics of giardiosis.
    Źródło:
    Wiadomości Parazytologiczne; 1995, 41, 1; 25-31
    0043-5163
    Pojawia się w:
    Wiadomości Parazytologiczne
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Zrodlo i znaczenie genetycznego zroznicowania populacji pasozytniczych pierwotniakow
    Autorzy:
    Majewska, A C
    Sulima, P.
    Powiązania:
    https://bibliotekanauki.pl/articles/837049.pdf
    Data publikacji:
    1999
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Tematy:
    zroznicowanie genetyczne
    Leishmania
    Giardia
    struktura populacji
    pierwotniaki
    parazytologia
    zroznicowanie gatunkowe
    Toxoplasma
    populacje zwierzat
    pasozyty
    Trypanosoma
    Cryptosporidium
    Opis:
    The application of biochemical and molecular techniques in parasitological studies has provided increasing evidences of genetic polymorphism among parasite populations. This review presents possible origins of genetic variation within populations of various protozoan species. Since the mode of reproduction has an important influence on genetic polymorphism within parasite populations these considerations refer mainly to some protozoan parasites which have various life cycles, e.g. Giardia, Trypanosoma, Cryptosporidium, Toxoplasma. Also other factors associated with parasites (such as: transmission and passage history in laboratory conditions; occurrence in different hosts or geographic regions; selective pressure of drugs; competitive interactions between populations) that affect parasite genetic diversity are discussed. However, the number of examined isolates of parasites and genetic markers, assortment of methods, probes, primers and reagents used is also of significance. The significance of genetic variability in parasite populations is still the subject of much interest and controversy. A simple interpretation of such variation is impossible because of the complexity of host-parasite interactions. The knowledge of parasite diversity at the nucleic acids level has continually increased, but a corect interpretation of this phenomenon requires at least the same knowledge of genetic variability in host populations. Nevertheless, genetic variability in protozoan parasites has many important implications, e.g. for taxonomy, epidemiology, control and evolution. Genetic differences within parasite populations might also be associated with phenotypic variability, e.g. virulence, antigenicity, infectivity, drug sensitivity, hostpreference etc.
    Źródło:
    Annals of Parasitology; 1999, 45, 3; 293-307
    0043-5163
    Pojawia się w:
    Annals of Parasitology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Źródło i znaczenie genetycznego zróżnicowania populacji pasożytniczych pierwotniaków
    SOURCE AND SIGNIFICANCE OF GENETIC POLYMORPHISM OF SELECTED PARASITIC PROTOZOA
    Autorzy:
    Majewska, A. C.
    Sulima, P.
    Powiązania:
    https://bibliotekanauki.pl/articles/2148795.pdf
    Data publikacji:
    1999
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Tematy:
    zroznicowanie genetyczne
    Leishmania
    Giardia
    struktura populacji
    pierwotniaki
    parazytologia
    zroznicowanie gatunkowe
    Toxoplasma
    populacje zwierzat
    pasozyty
    Trypanosoma
    Cryptosporidium
    Opis:
    The application of biochemical and molecular techniques in parasitological studies has provided increasing evidences of genetic polymorphism among parasite populations. This review presents possible origins of genetic variation within populations of various protozoan species. Since the mode of reproduction has an important influence on genetic polymorphism within parasite populations these considerations refer mainly to some protozoan parasites which have various life cycles, e.g. Giardia, Trypanosoma, Cryptosporidium, Toxoplasma. Also other factors associated with parasites (such as: transmission and passage history in laboratory conditions; occurrence in different hosts or geographic regions; selective pressure of drugs; competitive interactions between populations) that affect parasite genetic diversity are discussed. However, the number of examined isolates of parasites and genetic markers, assortment of methods, probes, primers and reagents used is also of significance. The significance of genetic variability in parasite populations is still the subject of much interest and controversy. A simple interpretation of such variation is impossible because of the complexity of host-parasite interactions. The knowledge of parasite diversity at the nucleic acids level has continually increased, but a corect interpretation of this phenomenon requires at least the same knowledge of genetic variability in host populations. Nevertheless, genetic variability in protozoan parasites has many important implications, e.g. for taxonomy, epidemiology, control and evolution. Genetic differences within parasite populations might also be associated with phenotypic variability, e.g. virulence, antigenicity, infectivity, drug sensitivity, hostpreference etc.
    Źródło:
    Wiadomości Parazytologiczne; 1999, 45, 3; 293-307
    0043-5163
    Pojawia się w:
    Wiadomości Parazytologiczne
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-8 z 8

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