- Tytuł:
- Relationship of c-myc and erbB oncogene family gene aberrations and other selected factors to ex vivo chemosensitivity of ovarian cancer in the modified ATP-chemosensitivity assay.
- Autorzy:
-
Vogt, Ulf
Falkiewicz, Bogdan
Bielawski, Krzysztof
Bosse, Ulrich
Schlotter, Claus - Powiązania:
- https://bibliotekanauki.pl/articles/1044426.pdf
- Data publikacji:
- 2000
- Wydawca:
- Polskie Towarzystwo Biochemiczne
- Tematy:
-
cultured tumor cells
antitumor drug screening assays
oncogenes
ovarian cancer
antineoplastic agents - Opis:
- A pilot study on relationships of selected molecular factors [erbB-1, erbB-2, erbB-3, and c-myc oncogene average gene copy numbers (AGCN); steroid receptors and pS2 gene expression; tumor cells' DNA values] to the ex vivo chemosensitivity of ovarian cancer in a modified adenosine triphosphate cell viability chemosensitivity assay (ATP-CVA), was performed. Despite the relatively small number of patients, numerous correlations among the factors tested were found. Nevertheless, only c-myc gene dosage positively affected ex vivo chemosensitivity of tumors tested.
- Źródło:
-
Acta Biochimica Polonica; 2000, 47, 1; 157-164
0001-527X - Pojawia się w:
- Acta Biochimica Polonica
- Dostawca treści:
- Biblioteka Nauki
Artykuł