- Tytuł:
- Effect of environmental parameters on the concentration of nickel (Ni) in bones of the hip joint from patients with osteoarthritis
- Autorzy:
-
Łanocha-Arendarczyk, Natalia
Kalisińska, Elżbieta
Kosik-Bogacka, Danuta
Budis, Halina
Lewicka, Katarzyna
Sokołowski, Sebastian
Dobiecki, Konrad
Kołodziej, Łukasz - Powiązania:
- https://bibliotekanauki.pl/articles/972587.pdf
- Data publikacji:
- 2016
- Wydawca:
- Instytut Medycyny Wsi
- Tematy:
-
bone
nickel
environmental exposure
implants - Opis:
- Introduction. Bone trace elements levels including nickel (Ni) depend on biological and environmental factors: age, gender, remodeling state, exposure to occupational and environmental pollution, smoking, diet, and surgical implants. Objective. The aim of this study was to determine Ni concentrations in bones of femur heads obtained from patients with osteoarthritis. Materials and method. A total of 111 samples of hip joint bones (cartilage, cancellous bone and compact bone) collected from patients from north-western Poland were examined. Ni concentration was determined by ICP-AES (atomic absorption spectrophotometry). Results. It was found that differences in Ni concentrations were statistically significant between cartilage and compact bone. Cartilage Ni concentrations were higher in patients with fractured femur neck than patients with osteoarthritis. Furthermore, higher Ni levels were also found in samples obtained from smokers compared to nonsmokers. In cancellous bone, higher Ni concentrations were found in samples from patients who had received implants than those without them. Moreover, higher Ni concentrations in cancellous bone were found in patients occupationally exposed to heavy metals than in those not exposed. Conclusions. The bone tissue reflects long-term exposure to Ni and may be used as a bioindicator to study the process of Ni accumulation in the human body.
- Źródło:
-
Journal of Pre-Clinical and Clinical Research; 2016, 10, 1; 6-11
1898-2395 - Pojawia się w:
- Journal of Pre-Clinical and Clinical Research
- Dostawca treści:
- Biblioteka Nauki
Artykuł