Temat: hydrogels - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: Fabrication and characterization of graphene-loaded chitosan hydrogels with cross-linking gradient
Autorzy:: Kosowska, K.
Domalik-Pyzik, P.
Chłopek, J.
Powiązania:: https://bibliotekanauki.pl/articles/285566.pdf
Data publikacji:: 2018
Wydawca:: Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Tematy:: hydrogels
chitosan
nanocomposites
Źródło:: Engineering of Biomaterials; 2018, 21, 148; 40
1429-7248
Pojawia się w:: Engineering of Biomaterials
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 2.

Tytuł:: Synthesis and characterization of novel chitosan nanocomposite hydrogels for drug delivery and bone tissue engineering
Autorzy:: Pazdan, K.
Pielichowska, K.
Chłopek, J.
Powiązania:: https://bibliotekanauki.pl/articles/285119.pdf
Data publikacji:: 2013
Wydawca:: Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Tematy:: nanocomposites
tissue engineering
hydrogels
Opis:: Biodegradable materials for drug delivery and bone tissue engineering are currently intensively developing and improving, but there are still a lot of problems to solve related with bioactivity, biocompatibility, release profile etc. Osteosarcoma is an aggressive malignant neoplasm arising from primitive transformed cells of mesenchymal origin that exhibit osteoblastic differentiation and produce malignant osteoid. It is the most common histological form of primary bone cancer [1,2]. Treatment is most destinations and made up for: intensive multidrug short induction chemotherapy, amputation or tumor resection within the limits of normal tissue and in the last phase again chemotherapy. This kind of neoplasm is most recently detected in young male till 25 age, therefore improving methods of treatment is so important. Chitosan is a natural-based polymer obtained by alkaline deacetylation of chitin received from powdered shrimp shells was purchased from Acros Organics. Its main advantages are non-toxic, non-immunogenic, non-carcinogenic degradation products, biocompatible, bioactive and biodegradable. These properties cause chitosan a very good candidate for novel hydrogel drug delivery systems. Chitosan easily forms hydrogel particles and entraps biomolecules through a number of mechanisms, including chemical crosslinking, ionic crosslinking, and ionic complexation [3,4]. A possible alternative of chitosan by the chemical modification also has been useful for the association of bioactive molecules to polymer and controlling the drug release profile. There are few methods of modification, or example.: copolimerization, grafting, chemical and ionic crosslinking, polyelectrolyte complexes, etc [5]. Previous studies demonstrated that chitosan could promote the proliferation and osteogenesis but only with moderate swelling ratio of composite, too high ability of entrapment water solutions are not recommended. There are a lot of advantages in chitosan properties that can be used in research work to obtain the material of the best expected properties. Laponite® (LA) is a plate-like synthetic clay hectoritetype belongs to a family of phyllosolicates type 2:1 [6]. Its structure represent empirical formula: Na0.7+[Si8Mg5.5Li0.3 O20(OH)4]0.7-. The plates size is about 25 nm x 0,92 nm. LA has a large surface area, anionic surface charges and exchangeable Na+ cations in hydrated interlayers. Presence of sodium cations causes better adsorption properties for cationic drug molecules. Moreover, the exfoliated LA particles may act as multifunctional crosslinkers in forming the nanocomposite hydrogels, and the polymer chains were anchored to the particles and entangled to form a network [7]. Used synthetic clay has got the same type structure and but better sorption properties to montmorillonite but it has got serious advantage - as a synthetic compound shows low heavy metal content. The initial results indicate that the incorporation of clay improved the swelling behavior in contrast to the pure chitosan beads. There also had been revealed significant disproportion of viscosity received hydrogels according to different type of LA or different concentration. Increasing content causes telling rise of viscosity, especially reported in higher content of used crosslinker. The aim of research is to develop a bioactive system biopolymer/layered silicate intelligent nanocomposite based on chitosan and synthetic clay by a cross-linking reaction using sodium tripolyphosphate as the gel factor. The resultant composite were characterized by Fourier transform infrared spectroscopy, scanning electronic microscope and X-ray diffraction analysis. The bioactivity in physiological pH solution (SBF pH=7.40) [8], drug encapsulation efficiency and controlled release behaviour were also investigated by using the model drug to reveal the effects of introduced LA.
Źródło:: Engineering of Biomaterials; 2013, 16, no. 122-123 spec. iss.; 1-2
1429-7248
Pojawia się w:: Engineering of Biomaterials
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 3.

Tytuł:: Naturally-derived hydrogels and nanocomposites as building blocks of scaffolds for tissue regeneration
Autorzy:: Stancu, I. C.
Drăgușin-Zakman, D. M.
Serafim, A.
Cecoltan, S.
Lungu, A.
Vasile, E.
Powiązania:: https://bibliotekanauki.pl/articles/284242.pdf
Data publikacji:: 2018
Wydawca:: Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Tematy:: hydrogels
nanocomposites
tissue regeneration
Źródło:: Engineering of Biomaterials; 2018, 21, 148; 8
1429-7248
Pojawia się w:: Engineering of Biomaterials
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 4.

Tytuł:: Chitosan hydrogels modified with silk, graphene oxide or reduced graphene oxide
Autorzy:: Szaraniec, Barbara
Boruchowski, Marcin
Gryń, Karol
Chłopek, Jan
Powiązania:: https://bibliotekanauki.pl/articles/1844967.pdf
Data publikacji:: 2020
Wydawca:: Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Tematy:: hydrogels
nanocomposites
chitosan
hydrożele
nanokompozyty
Źródło:: Engineering of Biomaterials; 2020, 23, 158 spec. iss.; 44
1429-7248
Pojawia się w:: Engineering of Biomaterials
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 5.

Tytuł:: Chitosan hydrogels modified with silk, graphene oxide or reduced graphene oxide
Autorzy:: Szaraniec, Barbara
Boruchowski, Marcin
Gryń, Karol
Chłopek, Jan
Powiązania:: https://bibliotekanauki.pl/articles/1844881.pdf
Data publikacji:: 2020
Wydawca:: Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Tematy:: hydrogels
nanocomposites
chitosan
hydrożele
nanokompozyty
chitozan
Źródło:: Engineering of Biomaterials; 2020, 23, 158 spec. iss.; 44
1429-7248
Pojawia się w:: Engineering of Biomaterials
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 6.

Tytuł:: Radiolytic synthesis of gold nanoparticles in HEMA-based hydrogels : potentialities for imaging nanocomposites
Autorzy:: Dziarabina, Katsiaryna
Pinaeva, Uliana
Kadłubowski, Sławomir
Ulański, Piotr
Coqueret, Xavier
Powiązania:: https://bibliotekanauki.pl/articles/2055680.pdf
Data publikacji:: 2021
Wydawca:: Instytut Chemii i Techniki Jądrowej
Tematy:: functional hydrogels
gold nanoparticles
nanocomposites
network properties
radiation--induced reactions
stimuli-responsiveness
Opis:: This article reports on the radiolytic synthesis of nanocomposites containing gold nanoparticles (AuNPs) within two types of hydrogels based on 2-hydroxyethyl methacrylate (HEMA): (i) plain networks with various contents in ethylene glycol dimethacrylate (EGDMA), as a cross-linker and (ii) stimuli-responsive (SR) networks prepared from these monomers copolymerized with [2-(methacryloyloxy)ethyl]trimethylammonium chloride (MADQUAT) to confer pH-switchable swelling. Hydrogels were prepared by photopolymerization with well-defi ned composition and a high degree of monomer conversion using two experimental procedures, as xerogels or in aqueous solution. Besides MADQUAT, acrylic acid (AA) or N-isopropylacrylamide have been tested as copolymers, yielding pH- or temperature-sensitive hydrogels, respectively. Isothermal swelling in water was affected by monomer composition. Electron beam (EB) irradiation at doses up to 100 kGy of poly(HEMA) xerogels and water-swollen networks prepared with 0.5 wt% of EGDMA had a moderate impact on swelling characteristics and thermomechanical properties of the plain materials, whereas small amounts of extractables were formed. Poly(HEMA)-based nanocomposites containing AuNPs were successfully obtained by EB irradiation of samples swollen by aqueous solutions of Au(III). The effects of dose and cross-linking density on the formation of AuNPs were monitored by UV-visible spectroscopy. Irradiation at well-defined temperatures of the Au(III)-loaded SR hydrogels induced the formation of nanoparticles with size-dependent features, whereas the efficiency of Au(III) reduction at 10 kGy was not significantly affected by the network structure. EB-induced reduction of Au(III) in poly(HEMA) hydrogels using a lead mask to generate well-defined patterns yielded coloured and long-lasting images in the zones where the nanocomposite was formed.
Źródło:: Nukleonika; 2021, 66, 4; 165--177
0029-5922
1508-5791
Pojawia się w:: Nukleonika
Dostawca treści:: Biblioteka Nauki

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