Autor: Chai, G. - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: Bioinspired, biomimetic, double-enzymatic mineralization of hydrogels for bone regeneration with calcium carbonate
Autorzy:: Lopez-Heredia, M. A.
Łapa, A.
Mendes, A. C.
Balcaen, L.
Samal, S. K.
Chai, F.
Voort, P. van der
Stevens, C. V.
Parakhonskiy, B. V.
Chronakis, I. S.
Vanhaecke, F.
Blanchemain, N.
Pamuła, E.
Skirtach, A. G.
Douglas, T. E. L.
Powiązania:: https://bibliotekanauki.pl/articles/285532.pdf
Data publikacji:: 2016
Wydawca:: Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Tematy:: hydrogels
bone regeneration
mineralization
Źródło:: Engineering of Biomaterials; 2016, 19, 138; 109
1429-7248
Pojawia się w:: Engineering of Biomaterials
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 2.

Tytuł:: Phenolic plant extract enrichment of enzymatically mineralized hydrogels
Autorzy:: Douglas, Timothy E.L
Lopez-Heredia, Marco A.
Pułczyńska, Aleksandra
Łapa, Agata
Pietryga, Krzysztof
Schaubroeck, David
Santos, Sónia A.O.
Pais, Adriana
Brackman, Gilles
Schamphelaere, Karel de
Samal, Sangram Keshari
Keppler, Julia K.
Bauer, Jonas L
Chai, Feng
Blanchemain, Nicolas
Coenye, Tom
Pamuła, Elżbieta
Skirtach, Andre G
Powiązania:: https://bibliotekanauki.pl/articles/284057.pdf
Data publikacji:: 2019
Wydawca:: Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Tematy:: hydrogel
mineralization
polyphenols
antibacterial
epigallocatechin gallate
gellan gum
Opis:: Hydrogel mineralization with calcium phosphate (CaP) and antibacterial activity are desirable for applications in bone regeneration. Mineralization with CaP can be induced using the enzyme alkaline phosphatase (ALP), responsible for CaP formation in bone tissue. Incorporation of polyphenols, plant-derived bactericidal molecules, was hypothesized to provide antibacterial activity and enhance ALP-induced mineralization. Three phenolic rich plant extracts from: (i) green tea, rich in epigallocatechin gallate (EGCG) (herafter referred to as EGCG-rich extract); (ii) pine bark and (iii) rosemary were added to gellan gum (GG) hydrogels and subsequently mineralized using ALP. The phenolic composition of the three extracts used were analyzed by ultra-high-performance liquid chromatography coupled to tandem mass spectrometry (UHPLC-MSn). EGCG-rich extract showed the highest content of phenolic compounds and promoted the highest CaP formation as corroborated by dry mass percentage meassurements and ICP-OES de-termination of mass of elemental Ca and P. All three extracts alone exhibited antibacterial activity in the following order EGCG-rich > PI > RO, respectively. However, extract-loaded and mineralized GG hydro-gels did not exhibit appreciable antibacterial activity by diffusion test. In conclusion, only the EGCG-rich extract promotes ALP-mediated mineralization.
Źródło:: Engineering of Biomaterials; 2019, 22, 149; 2-9
1429-7248
Pojawia się w:: Engineering of Biomaterials
Dostawca treści:: Biblioteka Nauki

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