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    Wyświetlanie 1-8 z 8
    Tytuł:
    Eosinophil and IgE antibody responses against Uncinaria stenocephala larvae during dermal phase of the infection
    Autorzy:
    Gorski, P.
    Krawiec, M.
    Wedrychowicz, H.
    Powiązania:
    https://bibliotekanauki.pl/articles/837422.pdf
    Data publikacji:
    1998
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Tematy:
    parasite
    mouse
    infection
    mice
    eosinophil
    ELISA test
    Uncinaria stenocephala
    larva
    post-infection tissue
    host-parasite relationship
    antibody response
    Źródło:
    Annals of Parasitology; 1998, 44, 3
    0043-5163
    Pojawia się w:
    Annals of Parasitology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Preliminary evaluation of maternotoxic effect of Ascaris alpha-chymotrypsin inhibitor in mice
    WSTĘPNA OCENA TOKSYCZNEGO DZIAŁANIA INHIBITORA о-СНУМОТВУРЗУМУ 7 ASCARIS NA ORGANIZM CIĘŻARNYCH MYSZY
    Autorzy:
    Blaszkowska, J.
    Kadłubowski, R.
    Powiązania:
    https://bibliotekanauki.pl/articles/2148308.pdf
    Data publikacji:
    2001
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Tematy:
    parasite
    pregnancy
    mouse
    mice
    Ascaris
    host organism
    toxic effect
    alpha-chymotrypsin inhibitor
    Opis:
    Administration intraperitoneally of the Ascaris α-chymotrypsin inhibitor (40-300 mg/kg/day.) at a late stage of organogenesis (8-12 days of gestation) disturbed course of mouse pregnancy. The low doses of α-chymotrypsin inhibitor (40-80 mg/kg/day) significantly decreased the number of live fetuses per litter, increased the number of fetal resorptions. The symptoms of matemal toxicity that occurred after administration of the highest doses of the inhibitor (80-300 mg/kg/day) to pregnant mice included: decreased body weight gain as compared to control, vaginal hemorrhage, intrauterine resorption of litters, abortions, altered behaviour of animals immediately after injection and death. There is a linear interrelationship between the logarithm of the doses of the inhibitor and mortality of pregnant mice. The DL50 value of the inhibitor for female was 116 mg/kg /day (confidence interval: 95.5-140.0 mg/kg/day).
    Źródło:
    Wiadomości Parazytologiczne; 2001, 47, 4; 705-710
    0043-5163
    Pojawia się w:
    Wiadomości Parazytologiczne
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Glutathione-S-transferase activity in mouse muscle during experital trichinellosis
    Autorzy:
    Derda, M.
    Wandurska-Nowak, E.
    Boczoń, K.
    Powiązania:
    https://bibliotekanauki.pl/articles/2147897.pdf
    Data publikacji:
    2001
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Tematy:
    parasite
    glutathione s-transferase
    infection
    muscle
    mouse
    Trichinella
    mice
    trichinellosis
    host
    skeletal muscle
    Opis:
    The role of glutathione-S-transferase (GST, EC 2.5.1.18) in biochemical host defence in experimental trichinellosis was evaluated. The activity of GST in mouse skeletal muscles was measured during the muscular phase of trichinellosis, starting from the 3rd week post infection (w.p.i.) to the 11th w.p.i. Activity was determined spectrophotometrically by monitoring the formation of thioether (S-2,4-dinitrophenylglutathione) from the reduced form of glutathione and 1-chloro-2,4-dinitrobenzene used as a substrate and as an example of xenobiotics. The changes in the activity of GST were as follows: an increase in activity starts in the 4th w.p.i., peaks (up to 310% of the normal value) in the 6th w.p.i., decreases in the 8th week and a final, weak rise was observed in week 11. The statistically significant changes in GST activity in this phase of experimental trichinellosis suggest that this enzyme participates in the biochemical defence of the host against Trichinella infection.
    Źródło:
    Wiadomości Parazytologiczne; 2001, 47, 2; 227-232
    0043-5163
    Pojawia się w:
    Wiadomości Parazytologiczne
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Preliminary evaluation of maternotoxic effect of Ascaris alpha-chymotrypsin inhibitor in mice
    Autorzy:
    Blaszkowska, J
    Kadlubowski, R.
    Powiązania:
    https://bibliotekanauki.pl/articles/839388.pdf
    Data publikacji:
    2001
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Tematy:
    parasite
    pregnancy
    mouse
    mice
    Ascaris
    host organism
    toxic effect
    alpha-chymotrypsin inhibitor
    Opis:
    Administration intraperitoneally of the Ascaris α-chymotrypsin inhibitor (40-300 mg/kg/day.) at a late stage of organogenesis (8-12 days of gestation) disturbed course of mouse pregnancy. The low doses of α-chymotrypsin inhibitor (40-80 mg/kg/day) significantly decreased the number of live fetuses per litter, increased the number of fetal resorptions. The symptoms of matemal toxicity that occurred after administration of the highest doses of the inhibitor (80-300 mg/kg/day) to pregnant mice included: decreased body weight gain as compared to control, vaginal hemorrhage, intrauterine resorption of litters, abortions, altered behaviour of animals immediately after injection and death. There is a linear interrelationship between the logarithm of the doses of the inhibitor and mortality of pregnant mice. The DL50 value of the inhibitor for female was 116 mg/kg /day (confidence interval: 95.5-140.0 mg/kg/day).
    Źródło:
    Annals of Parasitology; 2001, 47, 4
    0043-5163
    Pojawia się w:
    Annals of Parasitology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Immunomodelating influence of glicocorticosteroids-methylprednisolone acetate and dexamethasone on course of experimental infection BALB-c mice with L2 Toxocara canis
    Autorzy:
    Borecka, A.
    Powiązania:
    https://bibliotekanauki.pl/articles/836391.pdf
    Data publikacji:
    1998
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Tematy:
    parasite
    mouse
    mice
    toxocariasis
    dog
    nematode
    larva
    dexamethasone
    Toxocara canis
    host
    glicocorticosteroid-methylprednisolone acetate
    Źródło:
    Annals of Parasitology; 1998, 44, 3
    0043-5163
    Pojawia się w:
    Annals of Parasitology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Glutathione-S-transferase activity in mouse muscle during experital trichinellosis
    Autorzy:
    Derda, M
    Wandurska-Nowak, E.
    Boczon, K.
    Powiązania:
    https://bibliotekanauki.pl/articles/837806.pdf
    Data publikacji:
    2001
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Tematy:
    parasite
    glutathione s-transferase
    infection
    muscle
    mouse
    Trichinella
    mice
    trichinellosis
    host
    skeletal muscle
    Opis:
    The role of glutathione-S-transferase (GST, EC 2.5.1.18) in biochemical host defence in experimental trichinellosis was evaluated. The activity of GST in mouse skeletal muscles was measured during the muscular phase of trichinellosis, starting from the 3rd week post infection (w.p.i.) to the 11th w.p.i. Activity was determined spectrophotometrically by monitoring the formation of thioether (S-2,4-dinitrophenylglutathione) from the reduced form of glutathione and 1-chloro-2,4-dinitrobenzene used as a substrate and as an example of xenobiotics. The changes in the activity of GST were as follows: an increase in activity starts in the 4th w.p.i., peaks (up to 310% of the normal value) in the 6th w.p.i., decreases in the 8th week and a final, weak rise was observed in week 11. The statistically significant changes in GST activity in this phase of experimental trichinellosis suggest that this enzyme participates in the biochemical defence of the host against Trichinella infection.
    Źródło:
    Annals of Parasitology; 2001, 47, 2
    0043-5163
    Pojawia się w:
    Annals of Parasitology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Long term monitoring of Babesia microti infection in BALB-c mice using nested PCR
    Autorzy:
    Welc-Faleciak, R
    Bajer, A.
    Bednarska, M.
    Paziewska, A.
    Sinski, E.
    Powiązania:
    https://bibliotekanauki.pl/articles/50509.pdf
    Data publikacji:
    2007
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    parasite
    mouse
    infection
    mice
    Babesia microti
    blood
    monitoring
    BALB-c mice
    Piroplasmida
    rodent host
    Apicomplexa
    Opis:
    In this study we report the usefulness of nested PCR for screening of the persistent B. microti infections in rodent hosts. Female BALB/c mice were inoculated with 100 μl of donor blood infected with B. microti. Infections were detected using microscopic examination of Giemsa-stained blood smears. To determine whether B. microti DNA was present in blood and/or spleen tissue, nested PCR was performed targeting a specifi c fragment of the gene encoding the 18S rRNA. Blood was sampled every 10 days post-infection (dpi) until day 30, after which mice were sampled every 30 days until the end of experiment at 360 dpi. The most extensive parasitaemia (39% of infected erythrocytes) was observed at 10 dpi. Between 20-60 dpi, less then 1% of infected erythrocytes were detected in blood smears, and from 90 dpi onwards, infected erythrocytes were no longer observed. B. microti DNA was successfully amplifi ed from the blood of mice from 10 dpi until 180 dpi, as well as from spleens of infected mice at 10 and 20 dpi. The presented results show that nested PCR is the method of choice for monitoring infections of B. microti in the blood of rodent hosts, and could therefore be a tool for environmental monitoring of naturally infected rodents which are the predominant source of infection for tick vectors.
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2007, 14, 2
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    IgG antibody and eosinophil responses during heterologous infection of BALB-c mice with Trichinella spiralis and Heligmosomoides polygyrus
    Autorzy:
    Doligalska, M.
    Mijal, J.
    Laskowska, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/840273.pdf
    Data publikacji:
    1998
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Tematy:
    T helper cell
    parasite
    mouse
    mice
    host response
    heterologous infection
    eosinophil
    Heligmosomoides polygyrus
    Trichinella spiralis
    T cell
    antibody
    Źródło:
    Annals of Parasitology; 1998, 44, 3
    0043-5163
    Pojawia się w:
    Annals of Parasitology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-8 z 8

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