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    Wyświetlanie 1-15 z 15
    Tytuł:
    Biochemical investigations of the dynamics of proteinase activity at different stages of trichinellosis in mice
    Autorzy:
    Hadas, E
    Derda, M.
    Boczon, K.
    Wandurska-Nowak, E.
    Powiązania:
    https://bibliotekanauki.pl/articles/839657.pdf
    Data publikacji:
    1994
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Tematy:
    Trichinella pseudospiralis
    mice
    blood serum
    proteinase activity
    enzyme activity
    enzymatic change
    mouse
    muscle
    man
    trichinellosis
    Trichinella spiralis
    dynamics
    tissue
    Opis:
    In the literature available hitherto there are many reports on enzymatic changes in tissues and a correlated rise in enzymatic activity in blood serum during experimental and human trichinellosis. In this study we were characterised proteinase activity in crude extracts from muscles of mice infected with Trichinella spiralis and T. pseudospiralis and the dynamics of their changes in different stages of disease. The activity of proteinase in muscle of mice infected with T. spiralis showed an increase in the 1 st- 5th week post infection, and then a slight decrease. The biggest proteinase activity was observed in 5th- 6th week post infection. In the muscle of mice infected with T. pseudospiralis the increase of proteinase activity was observed in 1st-4th week post infection. In the 4th week the activity reached its maximum and in the 5th- 10th week post infection there was a decrease of the activity in comparison with the control. As we could see, the dynamics of the changes of proteinase activity in mice is similar in the case of the disease with other biochemical and immunological indices observed in trichinellosis and with the increase of regeneration and transformation processes observed in histopathological studies.
    Źródło:
    Annals of Parasitology; 1994, 40, 4
    0043-5163
    Pojawia się w:
    Annals of Parasitology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The effect of methylprednisolone on the dynamics of oxygen uptake and peroxidase and superoxide dismutase activities in skeletal muscles of mice infected with Trichinella spiralis larvae
    Autorzy:
    Wandurska-Nowak, E.
    Boczon, K.
    Derda, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/838559.pdf
    Data publikacji:
    1998
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Tematy:
    parasite
    superoxide dismutase
    mouse
    mice
    larva
    peroxidase
    Trichinella spiralis
    skeletal muscle
    Źródło:
    Annals of Parasitology; 1998, 44, 3
    0043-5163
    Pojawia się w:
    Annals of Parasitology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Glutathione-S-transferase activity in mouse muscle during experital trichinellosis
    Autorzy:
    Derda, M.
    Wandurska-Nowak, E.
    Boczoń, K.
    Powiązania:
    https://bibliotekanauki.pl/articles/2147897.pdf
    Data publikacji:
    2001
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Tematy:
    parasite
    glutathione s-transferase
    infection
    muscle
    mouse
    Trichinella
    mice
    trichinellosis
    host
    skeletal muscle
    Opis:
    The role of glutathione-S-transferase (GST, EC 2.5.1.18) in biochemical host defence in experimental trichinellosis was evaluated. The activity of GST in mouse skeletal muscles was measured during the muscular phase of trichinellosis, starting from the 3rd week post infection (w.p.i.) to the 11th w.p.i. Activity was determined spectrophotometrically by monitoring the formation of thioether (S-2,4-dinitrophenylglutathione) from the reduced form of glutathione and 1-chloro-2,4-dinitrobenzene used as a substrate and as an example of xenobiotics. The changes in the activity of GST were as follows: an increase in activity starts in the 4th w.p.i., peaks (up to 310% of the normal value) in the 6th w.p.i., decreases in the 8th week and a final, weak rise was observed in week 11. The statistically significant changes in GST activity in this phase of experimental trichinellosis suggest that this enzyme participates in the biochemical defence of the host against Trichinella infection.
    Źródło:
    Wiadomości Parazytologiczne; 2001, 47, 2; 227-232
    0043-5163
    Pojawia się w:
    Wiadomości Parazytologiczne
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Biochemical investigations of the dynamics of proteinase activity at different stages of trichinellosis in mice
    Autorzy:
    Hadaś, E.
    Derda, M.
    Boczoń, K.
    Wandurska-Nowak, E.
    Powiązania:
    https://bibliotekanauki.pl/articles/2151484.pdf
    Data publikacji:
    1994
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Tematy:
    Trichinella pseudospiralis
    mice
    blood serum
    proteinase activity
    enzyme activity
    enzymatic change
    mouse
    muscle
    man
    trichinellosis
    Trichinella spiralis
    dynamics
    tissue
    Opis:
    In the literature available hitherto there are many reports on enzymatic changes in tissues and a correlated rise in enzymatic activity in blood serum during experimental and human trichinellosis. In this study we were characterised proteinase activity in crude extracts from muscles of mice infected with Trichinella spiralis and T. pseudospiralis and the dynamics of their changes in different stages of disease. The activity of proteinase in muscle of mice infected with T. spiralis showed an increase in the 1 st- 5th week post infection, and then a slight decrease. The biggest proteinase activity was observed in 5th- 6th week post infection. In the muscle of mice infected with T. pseudospiralis the increase of proteinase activity was observed in 1st-4th week post infection. In the 4th week the activity reached its maximum and in the 5th- 10th week post infection there was a decrease of the activity in comparison with the control. As we could see, the dynamics of the changes of proteinase activity in mice is similar in the case of the disease with other biochemical and immunological indices observed in trichinellosis and with the increase of regeneration and transformation processes observed in histopathological studies.
    Źródło:
    Wiadomości Parazytologiczne; 1994, 40, 4; 329-335
    0043-5163
    Pojawia się w:
    Wiadomości Parazytologiczne
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The effects of di-n-butyl phthalate on the germ cells of laboratory mice
    Wpływ ftalanu di-n-butylu na komórki płciowe myszy laboratoryjnych
    Autorzy:
    Dobrzynska, M.M.
    Tyrkiel, E.J.
    Hernik, A.
    Derezinska, E.
    Goralczyk, K.
    Ludwicki, J.K.
    Powiązania:
    https://bibliotekanauki.pl/articles/873422.pdf
    Data publikacji:
    2009
    Wydawca:
    Narodowy Instytut Zdrowia Publicznego. Państwowy Zakład Higieny
    Tematy:
    germ cell
    laboratory animal
    mice
    mouse
    di-n-butyl phthalate
    plasticizer
    DNA damage
    micronucleus
    phthalate residue
    sperm quantity
    sperm quality
    Opis:
    Phthalate are found in the environmental samples due to their wide use in the industry as plasticizers. Di-n-butyl phthalate (DBP) is mainly used in nitrocellulose and polyvinyl acetate products as well as in personal-care products. This study was performed to investigate the influence of exposure to DBP on the quantity and quality (motility, morphology) and DNA damage (induction of micronuclei and DNA strand breaks) of male mice gametes. The estimation of DBP residues was also done. Eight weeks exposure to DBP (500 mg/kg bw and 2000 mg/kg bw) did not significantly affect testes and epididymes weights as well as sperm count. DBP clearly diminished sperm motility, enhanced frequency of abnormal sperm heads and not significantly increased DNA strand breaks in germ cells as well as frequency of micronuclei in spermatids. There were no bioacumulation of DBP in mice. Results suggest that DBP may affect the male mice germ cells.
    Ftalany są powszechnie wykorzystywane w przemyśle jako plastyfikatory, dlatego też często występują w próbach środowiskowych. Ftalan di-n-butylu (DBP) jest składnikiem produktów nitrocelulozowych i poliwinylowych, jak również produktów do higieny osobistej. Celem pracy było zbadanie wpływu podawania DBP na ilość i jakość gamet męskich myszy (ruchliwość, morfologia) oraz na występowanie uszkodzeń DNA (indukcja mikrojąder oraz pęknięć nici DNA). Zbadano także stężenie pozostałości DBP w gametach. Ośmiotygodniowe narażanie na DBP (500 mg/kg mc i 2000 mg/kg mc) nie powodowało istotnych zmian w ciężarze jąder i najądrzy ani w liczebności plemników. Narażenie na DBP, zwłaszcza w dawce 2000 mg/kg mc wpływało wyraźnie na zmniejszenie ruchliwości plemników i zwiększenie odsetka plemników o nieprawidłowej budowie morfologicznej. Powodowało też nieznaczne zwiększenie pęknięć nici DNA w gametach oraz zwiększenie częstości występowania mikrojąder w spermatydach. Nie wykazano bioakumulacji DBP w gonadach samców myszy. Uzyskane wyniki sugerują, że DBP może oddziaływać niekorzystnie na męskie komórki rozrodcze myszy.
    Źródło:
    Roczniki Państwowego Zakładu Higieny; 2009, 60, 4
    0035-7715
    Pojawia się w:
    Roczniki Państwowego Zakładu Higieny
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Macrophages during infection with Trichinella spiralis in mice
    Autorzy:
    Karmanska, K
    Houszka, M.
    Widyma, A.
    Stefaniak, E.
    Powiązania:
    https://bibliotekanauki.pl/articles/837069.pdf
    Data publikacji:
    1997
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Tematy:
    larva capsule
    immunoenzymatic technique
    mouse
    infection
    mice
    trichinellosis
    macrophage
    monoclonal antibody
    Trichinella spiralis
    muscle tissue
    Opis:
    Behaviour of macrophages in experimental mice trichinellosis, was investigated using the immunoenzymatic technique with monooclonal antibodies CD11b/CD18 within the framework of avidin-biotin-DAB. The maximum and earliest mobilization of macrophages 7 day post infection (dpi) was observed in the lamina propria of the intestinal mucosa. The highest level of macrophages in the muscles tissue was noted on day 21 of infection, however as early as in 28 dpi, their maximum level was observed inside the larval capsules. They line, especially between 35-42 dpi internal capsule surphace.
    Źródło:
    Annals of Parasitology; 1997, 43, 3
    0043-5163
    Pojawia się w:
    Annals of Parasitology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Macrophages during infection with Trichinella spiralis in mice
    Autorzy:
    Karmańska, K.
    Houszka, M.
    Widyma, A.
    Stefaniak, E.
    Powiązania:
    https://bibliotekanauki.pl/articles/2148900.pdf
    Data publikacji:
    1997
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Tematy:
    larva capsule
    immunoenzymatic technique
    mouse
    infection
    mice
    trichinellosis
    macrophage
    monoclonal antibody
    Trichinella spiralis
    muscle tissue
    Opis:
    Behaviour of macrophages in experimental mice trichinellosis, was investigated using the immunoenzymatic technique with monooclonal antibodies CD11b/CD18 within the framework of avidin-biotin-DAB. The maximum and earliest mobilization of macrophages 7 day post infection (dpi) was observed in the lamina propria of the intestinal mucosa. The highest level of macrophages in the muscles tissue was noted on day 21 of infection, however as early as in 28 dpi, their maximum level was observed inside the larval capsules. They line, especially between 35-42 dpi internal capsule surphace.
    Źródło:
    Wiadomości Parazytologiczne; 1997, 43, 3; 245-249
    0043-5163
    Pojawia się w:
    Wiadomości Parazytologiczne
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Glutathione-S-transferase activity in mouse muscle during experital trichinellosis
    Autorzy:
    Derda, M
    Wandurska-Nowak, E.
    Boczon, K.
    Powiązania:
    https://bibliotekanauki.pl/articles/837806.pdf
    Data publikacji:
    2001
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Tematy:
    parasite
    glutathione s-transferase
    infection
    muscle
    mouse
    Trichinella
    mice
    trichinellosis
    host
    skeletal muscle
    Opis:
    The role of glutathione-S-transferase (GST, EC 2.5.1.18) in biochemical host defence in experimental trichinellosis was evaluated. The activity of GST in mouse skeletal muscles was measured during the muscular phase of trichinellosis, starting from the 3rd week post infection (w.p.i.) to the 11th w.p.i. Activity was determined spectrophotometrically by monitoring the formation of thioether (S-2,4-dinitrophenylglutathione) from the reduced form of glutathione and 1-chloro-2,4-dinitrobenzene used as a substrate and as an example of xenobiotics. The changes in the activity of GST were as follows: an increase in activity starts in the 4th w.p.i., peaks (up to 310% of the normal value) in the 6th w.p.i., decreases in the 8th week and a final, weak rise was observed in week 11. The statistically significant changes in GST activity in this phase of experimental trichinellosis suggest that this enzyme participates in the biochemical defence of the host against Trichinella infection.
    Źródło:
    Annals of Parasitology; 2001, 47, 2
    0043-5163
    Pojawia się w:
    Annals of Parasitology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    CD4 and CD8 cells in mice infected with Trichinella spiralis and treated with cyclosporine A
    Autorzy:
    Karmanska, K
    Houszka, M.
    Mista, D.
    Stefaniak, E.
    Powiązania:
    https://bibliotekanauki.pl/articles/836501.pdf
    Data publikacji:
    1994
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Tematy:
    immunoenzymatic method
    mouse
    infection
    mice
    cell
    T lymphocyte
    immunofluorescent method
    cyclosporin A
    larva
    Trichinella spiralis
    Opis:
    Studies were undertaken to evaluate by parasitological techniques the course of intestinal and muscular invasions in mice infected with Trichinella spiralis and treated with TFX-Thymomodulin (TFX-Th). Studies were conducted on 120 mice of BALB/c and SWISS strains, infected each with a mean invasive dose of 300 T. spiralis larvae. TFX-Th (Thymoorgan GmbH Pharmazie Co. KG, Vienenburg, Germany) was administered subcutaneously at 30 mg/kg body weight. Depending upon duration of TFX-Th administration and stages of intestinal and muscular invasions, three experiments were distinguished in the study. The results indicated that TFX-Th promoted eradication of larvae from muscles, whether administered at the early of the late stage of T. spiralis invasion.
    Źródło:
    Annals of Parasitology; 1994, 40, 4
    0043-5163
    Pojawia się w:
    Annals of Parasitology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The influence of adriamycin on the CD4 and CD8 cells in the course of trichinellosis in mice
    Autorzy:
    Karmanska, K
    Houszka, M.
    Mista, D.
    Stefaniak, E.
    Powiązania:
    https://bibliotekanauki.pl/articles/837229.pdf
    Data publikacji:
    1994
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Tematy:
    parasite
    mouse
    mice
    cell
    trichinellosis
    adriamycin
    histopathology
    Opis:
    The effect of adriamycin on the behaviour of CD4⁺ and CD8⁺ cells in the course of trichinellosis in mice has been studied. The animals infected with 200 larvae per mouse were administered intraperitoneally adriamycin (Adriblastin from Farmitalia) at 1st and 28th day post infection (dpi), in a dosis of 0.2 mg. The mice were killed weakly for 6 weeks and then at the 60th dpi. The examinations were made on histologic sections from the spleen, mesenteric lymph node, jejunum and masseter muscle using immunofluorescent and immunoenzymatic methods with monoclonal antibody. The mice receiving adriamycin exhibited more CD8⁺ cells in the intestinal mucosa and by the end of the experiment also in the muscles in comparison with the control animals, which, however, did not affect the course of the infection.
    Źródło:
    Annals of Parasitology; 1994, 40, 4
    0043-5163
    Pojawia się w:
    Annals of Parasitology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The cells observed inside capsules of larvae in the course of experimental trichinellosis in mice
    Autorzy:
    Karmańska, K.
    Houszka, M.
    Widyma, A.
    Stefaniak, E.
    Powiązania:
    https://bibliotekanauki.pl/articles/2148907.pdf
    Data publikacji:
    1997
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Tematy:
    immunoenzymatic method
    larva capsule
    infection
    muscle
    mouse
    mice
    cell
    macrophage
    trichinellosis
    monoclonal antibody
    Opis:
    In the course of trichinellosis in mice the numerous cells inside larval capsules were observed. Beginning on 14 day post infection (dpi) they were seen in about 7% of infected muscles fibers but at 21 dpi the percentage of capsules with the cells amounted to 77. In the next stage of infection the number of capsules containing cells continued to increase and reach almost 100% at 60 dpi. The identification of the cells was carried out by the indirect immunoenzymatic method using anti-CD4⁺, anti-CD8⁺ and anti-macrophage (Mac-1 antigen) monoclonal antibodies. In course of observation the level of CD4⁺ cells decreased from 11.3 to 0.7, of CD8⁺ from 17.7 to 3.0 and of macrophages from 71.0 to 23.1 %. The most numerous CD4⁺ cells were seen at 14 dpi while the CD8⁺ and macrophages at 21 dpi. Beginning on 28 dpi negatively reacting cells inside larval capsules were also observed. The number of these cells increased from 23.8 to 73.2% at 60 dpi and their identification requires further investigations. The role and the function of all these cells are discussed.
    Źródło:
    Wiadomości Parazytologiczne; 1997, 43, 3; 251-256
    0043-5163
    Pojawia się w:
    Wiadomości Parazytologiczne
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    CD4+ and CD8+ cells in mice infected with Trichinella spiralis and treated with cyclosporine A
    Autorzy:
    Karmańska, K.
    Houszka, M.
    Miśta, D.
    Stefaniak, E.
    Powiązania:
    https://bibliotekanauki.pl/articles/2151487.pdf
    Data publikacji:
    1994
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Tematy:
    immunoenzymatic method
    mouse
    infection
    mice
    cell
    T lymphocyte
    immunofluorescent method
    cyclosporin A
    larva
    Trichinella spiralis
    Opis:
    Studies were undertaken to evaluate by parasitological techniques the course of intestinal and muscular invasions in mice infected with Trichinella spiralis and treated with TFX-Thymomodulin (TFX-Th). Studies were conducted on 120 mice of BALB/c and SWISS strains, infected each with a mean invasive dose of 300 T. spiralis larvae. TFX-Th (Thymoorgan GmbH Pharmazie Co. KG, Vienenburg, Germany) was administered subcutaneously at 30 mg/kg body weight. Depending upon duration of TFX-Th administration and stages of intestinal and muscular invasions, three experiments were distinguished in the study. The results indicated that TFX-Th promoted eradication of larvae from muscles, whether administered at the early of the late stage of T. spiralis invasion.
    Źródło:
    Wiadomości Parazytologiczne; 1994, 40, 4; 357-362
    0043-5163
    Pojawia się w:
    Wiadomości Parazytologiczne
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The effect of undecanones and their derivatives on tumor angiogenesis and VEGF content
    Autorzy:
    Gibka, J
    Wasiutynski, A.
    Skopinska-Rozewska, E.
    Siwicki, A.K.
    Chorostowska-Wynimko, J.
    Sommer, E.
    Mazurkiewicz, M.
    Glinski, M.
    Skurzak, H.
    Wojcik, R.
    Jung, L.
    Powiązania:
    https://bibliotekanauki.pl/articles/31734.pdf
    Data publikacji:
    2010
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    mice
    mouse
    undecan-x-one
    derivative
    angiogenesis
    tumour
    VEGF zob.vascular endothelial growth factor
    enantiomer
    histological examination
    vascular endothelial growth factor
    sarcoma cell
    Opis:
    The in vivo effects of some derivatives of aliphatic ketones (2-undecanone, 3-undecanone, 4-undecanone and their derivatives) on L-l sarcoma tumor angiogenesis and VEGF content were studied in Balb/c mice. Mice that inhaled 10% solution of 3-undecanone(3-on) or 1% solution of 2-undecanone propylene acetal (Acpr2) for 3 days after tumor cells implantation, presented lower neovascular response measured by tumor-induced cutaneous angiogenesis test (TIA) and lower tumor VEGF content in 5-days tumors, than non-inhaled controls. Other substances presented various effects on tumor VEGF concentration and angiogenesis. Histological examination of lesions collected from mice inhaled Acpr2, or non-inhaled controls, revealed small diffused areas of necrosis in the former group. In both groups, slight to moderate inflammatory infiltrations were seen at the tumor's margin. In Acpr2 group, there were less small blood vessels at tumor's margin than in the control group.
    Źródło:
    Polish Journal of Veterinary Sciences; 2010, 13, 1; 105-115
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    In vivo immuno - and angiomodulatory effects of Aloe arborescens folii recentis extractum siccum (AAES) in mice
    Autorzy:
    Zdanowski, R.
    Bałan, B.J.
    Schonknecht, K.
    Skopiński, P.
    Stelmasiak, M.
    Skopińska-Różewska, E.
    Lewicki, S.
    Powiązania:
    https://bibliotekanauki.pl/articles/2049078.pdf
    Data publikacji:
    2020
    Wydawca:
    Instytut Włókien Naturalnych i Roślin Zielarskich
    Tematy:
    Aloe arborescens
    herbal medicinal product
    Biostymina preparation
    Phytopharm Kleka
    water extract
    antibody response
    angiogenesis
    mice
    mouse
    wyciąg wodny z Aloe arborescens
    myszy
    splenocyty
    angiogeneza (test LIA)
    proliferacja komórek (PHA)
    produkcja przeciwciał
    Opis:
    Introduction: AAES is a powdered form of Biostymina, herbal medicinal product of Phytopharm Klęka S.A., a water extract of Aloe arborescens Mill. leaves. Aloe arborescens Mill. (woody aloe, tree-like aloe) is known to have several traditional medicinal properties including anti-inflammatory, immunomodulatory, antiviral and antimicrobial activity. Objective: The aim of this work was to study the in vivo effect of AAES on cellular (leukocyte-induced cutaneous angiogenesis, LIA test, and proliferative response to PHA) and humoral (anti-SRBC antibody response)immunity in mice. Methods: Balb/c mice were fed AAES from 0.5 to 75 mg/kg body mass for seven days before grafting their splenocytes intradermally to F1 (Balb/cxC3H) recipients (LIA test). Neovascular reaction was evaluated 72 h later in dissection microscope. Spleen cell cultures were incubated with 0.5, 1 and 2 µg/ml of PHA. After 48 h of incubation, tritiated thymidine was added. After further 24 h, cells were harvested (Skatron) and incorporation of tritiated thymidine was measured using Beta-scintillation counter. Balb/c mice were fed for 7 days with AAES, then immunized intraperitoneally with 5% SRBC suspension and 7 days later the antibody response was measured with hemagglutination test. Results: Neovascular reaction was significantly higher in groups grafted with splenocytes collected from all AAES fed donors than from the controls. The proliferation of splenocytes taken from mice fed AAES at doses ranging from 0.5 mg/kg to 7.5 mg/kg was stimulated in all cultures. Suppression of proliferation was observed in cell cultures derived from mice fed with higher doses of AAES. Stimulation of anti-SRBC antibody production was seen in mice fed both 2.5 and 7.5 mg/kg dose of AAES. Conclusion: Powdered form of Biostymina (AAES) might be useful in the treatment of patients with ischaemia of tissues and organs (myocardial infarction, stroke, necrosis) and in deficiency in the production of immune cells and growth factors (infections, chronic wound healing, ulceration and bone fusion).
    Źródło:
    Herba Polonica; 2020, 66, 3; 13-23
    0018-0599
    Pojawia się w:
    Herba Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Dose-dependent in vivo effect of Rhodiola and Echinacea on the mitogen-induced lymphocyte proliferation in mice
    Autorzy:
    Skopińska-Rozewska, E.
    Sokolnicka, I.
    Siwicki, A.K.
    Stankiewicz, W.
    Dabrowski, M.P.
    Buchwald, W.
    Krajewska-Patan, A.
    Mielcarek, S.
    Mscisz, A.
    Furmanowa, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/31333.pdf
    Data publikacji:
    2011
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    in vivo effect
    Rhodiola rosea
    Echinacea purpurea
    Echinacea angustifolia
    Rhodiola quadrifida
    mitogen-induced lymphocyte
    lymphocyte
    proliferation
    mice
    mouse
    Opis:
    Echinacea purpurea (EP) and Echinacea angustifolia (EA) are ones of the most important world’s herbs with immunotropic activity. They were traditional medicinal plants used by North American Indians for the treatment of various illnesses. Now they are cultivated in many countries and are used mainly to treat respiratory tract infections. Rhodiola rosea (RR) and Rhodiola quadrifida (RQ) are medicinal plants originated from Asia and used traditionally as adaptogens, antidepressants, and anti-inflammatory remedies. We previously reported, that extracts of underground parts of RR and RQ exhibited immunotropic activity. We have demonstrated in pigs that in vitro RR or RQ supplementation of blood lymphocyte cultures stimulated T cell proliferative response to Con A in lower, and inhibited it in higher Rhodiola extract concentrations. The aim of this work was to evaluate the in vivo effect of these herbal remedies on the in vitro proliferative response of mouse splenic lymphocytes to another T-cell mitogen- Phaseolus vulgaris haemagglutinin (PHA). We have found significant stimulation of proliferative response, in comparison to the controls, in mice fed lower doses of tested remedies, and inhibition, no effect or lower stimulation, in mice fed higher doses of these drugs.
    Źródło:
    Polish Journal of Veterinary Sciences; 2011, 14, 2
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-15 z 15

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