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Tytuł:
Current Highlights in the Use of Magnetic Resonance Spectroscopy in Multiple Sclerosis
Autorzy:
Kulczyński, Marcin
Walicka, Alicja
Marciniec, Michał
Sapko, Klaudia
Dyndor, Katarzyna
Powiązania:
https://bibliotekanauki.pl/articles/1058090.pdf
Data publikacji:
2019
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
Multiple sclerosis
N-acetylaspartate
brain metabolites
demyelination
magnetic resonance imaging
magnetic resonance spectroscopy
Opis:
Magnetic resonance spectroscopy is a non-invasive method used to measure concentrations of selected metabolites in brain such as: N-acetylaspartate, creatine, choline, glutamic acid, myo-inositol, lactic acid or γ-aminobutyric acid. The MRS allows the researcher to obtain information about biochemical composition in selected localizations of the examined CNS and is based on the interpretation of spectra of specific chemical compounds. The aim of this study is a literature review of papers from last 5 years involving the use of MRS in multiple sclerosis. Magnetic resonance spectroscopy is a modern, promising metabolomic imaging method enabling the assessment of brain metabolite concentrations and the dynamism of their changes in healthy people and patients suffering from multiple sclerosis at every stage of the disease. MRS is helpful not only in correlating changes in metabolite concentrations at various central nervous system locations with clinical manifestations, but is also an increasingly improving tool for predicting disease progression. Magnetic resonance spectroscopy may also be useful in more specific clinical situations such as differential diagnosis between multiple sclerosis and Devic’s syndrome or between tumefactive demyelinating lesions and gliomas. Especially in the latter case, the development of this technology may in the future result in the possibility of avoiding invasive biopsy in patients during the diagnosis of focal changes in the CNS. One should also not forget about the role that MRS may play in the future in monitoring the course of treatment with modern MS drugs, not only in everyday clinical practice but also at the stage of clinical trials. The development of fast MRS techniques, significantly shortening the acquisition time and 7 T magnetic resonance spectroscopy, precise and repeatable method of quantitative analysis of brain metabolites may be particularly helpful in achieving these goals.
Źródło:
World Scientific News; 2019, 134, 2; 187-197
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Increasing the signal to noise ratio in low-field MR scanner at department of nuclear and medical electronics
Techniki wzmocnienia stosunku sygnał-szum w niskopolowym skanerze MR w zakładzie elektroniki jądrowej i medycznej
Autorzy:
Wieteska, M.
Obrębski, W.
Piątkowska-Janko, E.
Sawionek, B.
Bogorodzki, P.
Powiązania:
https://bibliotekanauki.pl/articles/408155.pdf
Data publikacji:
2017
Wydawca:
Politechnika Lubelska. Wydawnictwo Politechniki Lubelskiej
Tematy:
magnetic resonance imaging
tomografia rezonansu magnetycznego
Opis:
This article presents studies carried by laboratory of Biomedical and Nucleonic Computer Systems. Our research concerns improvement of quality of imaging in low-field MRI scanner with field strength of 0.23 T as well as development of techniques of proton-electron dual resonance imaging and hyperpolarization of noble gases. Achieved results may contribute to improvement of multiple techniques of medical diagnostics, in particular functional study of lungs and heart as well as brain perfusion.
Niniejszy artykuł przedstawia przegląd prac prowadzonych przez zespół pracowni Biomedycznych i Nukleonicznych Systemów Komputerowych. Zaprezentowane badania dotyczą poprawy jakości obrazowania w niskopolowym skanerze rezonansu magnetycznego o indukcji pola głównego 0,23 T oraz rozwoju technik podwójnego rezonansu protonowo-elektronowego i hiperpolaryzacji gazów szlachetnych. Rezultaty naszych prac mogą przyczynić się do poprawy technik diagnostyki medycznej, w szczególności takich jak funkcjonalne badanie płuc i serca jak i perfuzja mózgu.
Źródło:
Informatyka, Automatyka, Pomiary w Gospodarce i Ochronie Środowiska; 2017, 7, 1; 133-136
2083-0157
2391-6761
Pojawia się w:
Informatyka, Automatyka, Pomiary w Gospodarce i Ochronie Środowiska
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Magnetic Resonance Elastography – noninvasive method to assess liver disease
Autorzy:
Ożóg, Łukasz
Aebisher, David
Bober, Zuzanna
Bartusik-Aebisher, Dorota
Guz, Wiesław
Cholewa, Marian
Powiązania:
https://bibliotekanauki.pl/articles/454714.pdf
Data publikacji:
2017
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
fibrosis
liver stiffness
MRE
magnetic resonance imaging
Opis:
Currently, liver disease is widespread and the awareness of these diseases is low. Early symptoms of liver disease do not necessarily indicate problems with this organ and patients are usually informed of their problems when the stage of the disease is already advanced. Invasive biopsies are the clinical diagnostic method most commonly used in the evaluation of liver disease. A biopsy is associated with a high risk of false results and additional complications. Finding new non-invasive imaging methods has led to the discovery of a new method called Magnetic Resonance Elastography (MRE). This technique allows one to evaluate the mechanical properties of tissues and to distinguish between pathological states. Testing using this technique can be performed on a conventional magnetic resonance system by using few additional components and properly prepared software. Studies have shown that there is a strong correlation between MRE-measured liver stiffness and the degree of fibrosis. MRE is also useful in characterizing liver tumors. Studies show that this technique is highly credible in both health volunteers and patients with liver fibrosis. MRE has tremendous diagnostic potential. The described technique is not currently widely used and has the 127-132potential to serve as a safe and accurate alternative in clinical diagnostics in the future.
Źródło:
European Journal of Clinical and Experimental Medicine; 2017, 2; 127-132
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Glycosaminoglycan concentration in cancer tissue
Autorzy:
Bar, Piotr
Galiniak, Sabina
Bartusik-Aebisher, Dorota
Filip, Rafał
Aebisher, David
Powiązania:
https://bibliotekanauki.pl/articles/454799.pdf
Data publikacji:
2019
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
fixed charge density glycosaminoglyca
magnetic resonance imaging
Opis:
Introduction. Glycosaminoglycans (GAGs) play a widespread role in tissue modelling. GAG polymers may affect several receptor pathways in parallel. Aim. To present difference in concentration of GAG in healthy and cancer tissues. Material and methods. The literature search was performed nd reviewed using selected keywords. Results. We revieved the methods of detection various types of glycans measured by Magnetic Resonance Imaging. Conclusion. MRI methodology provides an efficient tool forstudy of cellular composition. The use T1 aof T2 measurements to study cancer tissue is a promising assay.
Źródło:
European Journal of Clinical and Experimental Medicine; 2019, 2; 175-178
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
19F MRI As a tool for imaging drug delivery to tissue and individual cells
Autorzy:
Bober, Zuzanna
Aebisher, David
Ożóg, Łukasz
Tabarkiewicz, Jacek
Tutka, Piotr
Bartusik-Aebisher, Dorota
Powiązania:
https://bibliotekanauki.pl/articles/454941.pdf
Data publikacji:
2017
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
drug delivery
drug tracking
fluorine
magnetic resonance imaging
Opis:
Over the past few decades, magnetic resonance imaging (MRI) has proven to be extremely successful in medical applications. More recently, the biomedical applications of MRI have been gaining more use in the field of clinical pharmacy. In 1977, perfluorocarbon compounds (PFC), which form emulsions that can carry drugs, were analyzed by 19F MRI and emulsified PFC compounds have been investigated as potential blood substitutes since the early 1960s and now a wide variety of PFC compounds are currently available as 19F MRI biomarkers. Molecules with 19F substituents are particularly attractive for use in drug tracking by 19F MRI due to 100% 19F abundance, high 19F MRI sensitivity (0.83 relative to 1H MRI) and an impressively large chemical shift range (400 ppm). Another benefit in the use of 19F MRI is a zero background signal in biological samples due to lack of endogenous fluorine. Therefore, drugs containing fluorine atom have potential for 19F MRI imaging drug delivery to tissue. This article will review recent developments in the use of 19F MRI in imaging drug delivery to tissue and individual cells.
Źródło:
European Journal of Clinical and Experimental Medicine; 2017, 2; 99-109
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Compressed sensing in MRI : mathematical preliminaries and basic examples
Autorzy:
Błaszczyk, Ł.
Powiązania:
https://bibliotekanauki.pl/articles/146500.pdf
Data publikacji:
2016
Wydawca:
Instytut Chemii i Techniki Jądrowej
Tematy:
compressed sensing
magnetic resonance imaging
sampling theory
sparsity
Opis:
In magnetic resonance imaging (MRI), k-space sampling, due to physical restrictions, is very time- -consuming. It cannot be much improved using classical Nyquist-based sampling theory. Recent developments utilize the fact that MR images are sparse in some representations (i.e. wavelet coeffi cients). This new theory, created by Candès and Romberg, called compressed sensing (CS), shows that images with sparse representations can be recovered from randomly undersampled k-space data, by using nonlinear reconstruction algorithms (i.e. l1-norm minimization). Throughout this paper, mathematical preliminaries of CS are outlined, in the form introduced by Candès. We describe the main conditions for measurement matrices and recovery algorithms and present a basic example, showing that while the method really works (reducing the time of MR examination), there are some major problems that need to be taken into consideration.
Źródło:
Nukleonika; 2016, 61, 1; 41-43
0029-5922
1508-5791
Pojawia się w:
Nukleonika
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
MRI as a potential tool for monitoring of therapeutic monoclonal antibody distribution in cancer patients
Autorzy:
Tabarkiewicz, Jacek
Aebisher, David
Bartusik-Aebisher, Dorota
Powiązania:
https://bibliotekanauki.pl/articles/895617.pdf
Data publikacji:
2020-06-29
Wydawca:
Polskie Towarzystwo Farmaceutyczne
Tematy:
monoclonal antibody
magnetic resonance imaging
fluorine
cancer diagnostics
Opis:
Imaging and quantification of MAbs distribution by MRI after administration in vivo can improve patient outcomes, although it is not routinely used in the clinic hence the motivation for development of new MAbs imaging methodologies. Improvements in imaging and quantification of antibody distributions can be made by conjugating MAbs to “hotspot” atoms such as 19F as 19F Currently, research investigating the incorporation of 19F to antibody delivery systems has been limited to trastuzumab perfluorocarbon emulsions and this method has not been extended to other clinically approved antibodies. The methodologies of 19F MRI can improve current limitations of antibody immunotherapy such as quantitative visualization of targeted surface antigens expressed on tumor cells.
Źródło:
Acta Poloniae Pharmaceutica - Drug Research; 2020, 77, 3; 383-389
0001-6837
2353-5288
Pojawia się w:
Acta Poloniae Pharmaceutica - Drug Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Mixup (sample pairing) can improve the performance of deep segmentation networks
Autorzy:
Isaksson, Lars J.
Summers, Paul
Raimondi, Sara
Gandini, Sara
Bhalerao, Abhir
Marvaso, Giulia
Petralia, Giuseppe
Pepa, Matteo
Jereczek-Fossa, Barbara A.
Powiązania:
https://bibliotekanauki.pl/articles/2147117.pdf
Data publikacji:
2022
Wydawca:
Społeczna Akademia Nauk w Łodzi. Polskie Towarzystwo Sieci Neuronowych
Tematy:
magnetic resonance imaging
segmentation
prostate
data augmentation
mixup
Opis:
Researchers address the generalization problem of deep image processing networks mainly through extensive use of data augmentation techniques such as random flips, rotations, and deformations. A data augmentation technique called mixup, which constructs virtual training samples from convex combinations of inputs, was recently proposed for deep classification networks. The algorithm contributed to increased performance on classification in a variety of datasets, but so far has not been evaluated for image segmentation tasks. In this paper, we tested whether the mixup algorithm can improve the generalization performance of deep segmentation networks for medical image data. We trained a standard U-net architecture to segment the prostate in 100 T2-weighted 3D magnetic resonance images from prostate cancer patients, and compared the results with and without mixup in terms of Dice similarity coefficient and mean surface distance from a reference segmentation made by an experienced radiologist. Our results suggest that mixup offers a statistically significant boost in performance compared to non-mixup training, leading to up to 1.9% increase in Dice and a 10.9% decrease in surface distance. The mixup algorithm may thus offer an important aid for medical image segmentation applications, which are typically limited by severe data scarcity.
Źródło:
Journal of Artificial Intelligence and Soft Computing Research; 2022, 12, 1; 29--39
2083-2567
2449-6499
Pojawia się w:
Journal of Artificial Intelligence and Soft Computing Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Segmentacja wątroby w obrazach rezonansu magnetycznego
Liver segmentation in magnetic resonance images
Autorzy:
Paw, D.
Badura, P.
Powiązania:
https://bibliotekanauki.pl/articles/98720.pdf
Data publikacji:
2014
Wydawca:
Politechnika Śląska. Katedra Biomechatroniki
Tematy:
segmentacja
wątroba
rezonans magnetyczny
segmentation
liver
magnetic resonance imaging
Opis:
Celem niniejszej pracy było utworzenie algorytmu służącego do segmentacji wątroby w serii obrazów pochodzących z badania wykorzystującego rezonans magnetyczny. Rozwiązanie zostało zawarte w graficznym interfejsie użytkownika tworząc czytelny program. W algorytmie wykorzystano metodę aktywnego konturu, morfologię matematyczną oraz podobne przekształcenia. Wynikiem jest maska 3D oraz liczba wokseli w niej zawartych. Program umożliwia konfrontację wyników.
As a main aim of this project was made a liver segmentation algorithm from Magnetic Resonance Images. Whole solution was made in graphical user interface to make program simple and intuitive in use. In algorithm were used methods like: active contour (snake), mathematical morphology and similar transformations. As result is 3D mask of liver and sum of the voxels containing the mask. Application includes confrontation results.
Źródło:
Aktualne Problemy Biomechaniki; 2014, 8; 145-150
1898-763X
Pojawia się w:
Aktualne Problemy Biomechaniki
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Ekspozymetryczny profil narażenia zawodowego na pole magnetostatyczne przy tomografie rezonansu magnetycznego 1,5 T
Exposimetric profile of occupational exposure to static magnetic field of magnetic resonance scanner of 1.5 T
Autorzy:
Karpowicz, J.
Gryz, K.
Powiązania:
https://bibliotekanauki.pl/articles/261240.pdf
Data publikacji:
2010
Wydawca:
Politechnika Wrocławska. Wydział Podstawowych Problemów Techniki. Katedra Inżynierii Biomedycznej
Tematy:
tomograf
rezonans magnetyczny
narażenie zawodowe
ryzyko zawodowe
pole magnetostatyczne
badania ekspozymetryczne
MRI scanner
magnetic resonance imaging
occupational exposure
static magnetic field
exposimetric investigations
Opis:
W pracy scharakteryzowano ekspozymetryczne profile narażenia zawodowego techników i pielęgniarek na pole magnetostatyczne w czasie wykonywania badań diagnostycznych w tomografie rezonansu magnetycznego. Wyniki badań rzeczywistych warunków narażenia wykonanych ekspozymetrem hallotronowym w czasie rutynowych czynności przy badaniach pacjentów omówiono na przykładzie 16 czynności przy tomografie z magnesem 1,5 T. Czas narażenia na pole o indukcji przekraczającej 0,5 mT wynosi przy tych czynnościach 0,5-2,3 minuty, a czas narażenia przekraczającego 70 mT wynosi 0,0-0,3 minuty. Maksymalny poziom narażenia wynosi 16,8-126 mT.
In this paper, exposimetric profiles of occupational exposures of technicians and nurses to static magnetic fields during performing magnetic resonance imaging examinations, were characterized. Results of examination by hallotron exposimeter of the real exposure of the personnell performing 16 tasks in 1,5 T MRI scanner have been presented. Maximal exposure in the static magnetic field exceeding 0,5 mT is in the range 0,5-2,3 minutes and the exposure exceeding 70 mT is in the range 0,0-0,3 minutes. Maximum level of exposure is 16,8-126 mT.
Źródło:
Acta Bio-Optica et Informatica Medica. Inżynieria Biomedyczna; 2010, 16, 3; 261-264
1234-5563
Pojawia się w:
Acta Bio-Optica et Informatica Medica. Inżynieria Biomedyczna
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Contrast-enhanced Magnetic Resonance Imaging of lung cell cultures
Autorzy:
Bober, Zuzanna
Pogoda, Katarzyna
Aebisher, David
Tabarkiewcz, Jacek
Bartusik-Aebisher, Dorota
Powiązania:
https://bibliotekanauki.pl/articles/895529.pdf
Data publikacji:
2020-04-29
Wydawca:
Polskie Towarzystwo Farmaceutyczne
Tematy:
Lung cancer
cell cultures
magnetic resonance imaging
contrast media
Gadolinium
Opis:
Lung cancer is one of the most common types of cancer diagnosed, and the development of methods to image diseased lung tissue by MRI is of utmost importance. Contrast-Enhanced Magnetic Resonance Imaging (CE-MRI) was used to noninvasively evaluate spin-spin relaxation time, T1, of lung cell cultures infused with various clinical gadolinium-based contrast media for imaging. In this study we used a clinical 1.5 Tesla scanner and the contrast agents: Omniscan, MultiHance, Gadovist and ProHance. A significant five-fold reduction of T1 relaxation time was obtained.
Źródło:
Acta Poloniae Pharmaceutica - Drug Research; 2020, 77, 2; 251-258
0001-6837
2353-5288
Pojawia się w:
Acta Poloniae Pharmaceutica - Drug Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
MRgFUS – jako nowoczesna metoda leczenia
MRgFUS – as a modern treatment method
Autorzy:
Nowak, Bartłomiej
Powiązania:
https://bibliotekanauki.pl/articles/986652.pdf
Data publikacji:
2019
Wydawca:
Indygo Zahir Media
Tematy:
rezonans magnetyczny
ultradźwięki
termoablacja
MRgFUS
magnetic resonance imaging
ultrasounds
thermoablation
Opis:
Zabieg zogniskowaną wiązką ultradźwięków o wysokiej częstotliwości (FUS lub HIFU) pod kontrolą rezonansu magnetycznego (MRI) jest nieinwazyjną metodą termoablacji. Integracja FUS i MRI pozwala na precyzyjne zaplanowanie leczenia, określenie lokalizacji, wielkości interesującej nas zmiany oraz kontrole i monitorowanie w czasie rzeczywistym depozycji energii stosowanej w leczeniu bez uszkodzenia struktur sąsiadujących tkanek.
The treatment of a focused high frequency ultrasound beam (FUS or HIFU) under magnetic resonance imaging (MRI) is a non-invasive method of thermoablation. The integration of FUS and MRI allows for precise planning of treatment, determining the location, size of the changes that we are interested in, and real-time monitoring and monitoring of the deposition of energy used in treatment without damaging the structures of neighboring tissues.
Źródło:
Inżynier i Fizyk Medyczny; 2019, 8, 4; 333-336
2300-1410
Pojawia się w:
Inżynier i Fizyk Medyczny
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Juvenile nasopharyngeal angiofibroma with intracranial extension – diagnosis and treatment
Autorzy:
Gołąbek, Wiesław
Szymańska, Anna
Szymański, Marcin
Czekajska-Chehab, Elżbieta
Jargiełło, Tomasz
Powiązania:
https://bibliotekanauki.pl/articles/1397496.pdf
Data publikacji:
2020
Wydawca:
Index Copernicus International
Tematy:
computed tomography
intracranial invasion
juvenile nasopnaryngeal angiofibroma
magnetic resonance imaging
Opis:
Introduction: This retrospective study analyzes radiological findings, therapeutic management and outcomes of patients with intracranial extension of JNA. The routes of intracranial spread, incidence of intracranial disease and influence on therapeutic approach are discussed. Material and methods: An evaluation on the records of 62 patients with JNA was performed and 10 patients with intracranial tumors were included in the study. All patients were males aged 10 to 19 years. R esults: According to Andrews’ classification 8 patients presented with stage IIIb, 1 patient stage IVa and another patient stage IVb tumor. Intracranial invasion was extradural in 8 cases and intradural in 2 patient. Surgery was performed in 9 cases and the most common was combined approach: infratemporal fossa and sublabial transantral. One patient was referred for radiotherapy. Follow-up ranged from 8 to 26 years. There was extracranial recurrence in 2 (22%) of 9 operated patients. C onclusions: The superior orbital fissure is the most frequent route of intracranial spread in patients with extensive involvement of the infratemporal fossa. Due to high risk of recurrence and potential serious complications advanced cases of JNA should be managed by experienced multidisciplinary team, preferably in tertiary referral centers, with an access to modern diagnostic and therapeutic modalities.
Źródło:
Polish Journal of Otolaryngology; 2020, 74, 2; 1-7
0030-6657
2300-8423
Pojawia się w:
Polish Journal of Otolaryngology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Cerebral cavernous malformations: epidemiological, clinical and diagnostic imaging aspects
Autorzy:
Czekalska, I.
Tyrakowska-Dadełło, Z.
Werel, P.
Tarasów, E.
Grodzka, E.
Powiązania:
https://bibliotekanauki.pl/articles/1918780.pdf
Data publikacji:
2018
Wydawca:
Uniwersytet Medyczny w Białymstoku
Tematy:
CNS vascular malformations
cerebral cavernous malformation
computed tomography
magnetic resonance imaging
Opis:
Introduction: Cerebral cavernous malformations (CCMs) are one of the most common vascular malformations of the central nervous system. Symptoms of CCMs are not typical; the disease can be asymptomatic or be manifested by a wide range of neurological symptoms. Purpose: To evaluate chosen epidemiologic and clinical issues as well as advanced imaging diagnostics of CCMs in computed tomography and magnetic resonance imaging. Materials and methods: The study was based on retrospective analysis of CT and MRI examinations from the 5 years period. The analysis covered 61 persons, 29 males, and 32 females. The CCMs were diagnosed based on MRI examination in 43 patients and CT in 13 patients. Results: The rate of CCMs occurrence in own material was 0.2%. Single lesions were present in 90.2%, while multiple in 9.8% of cases. Supratentorial CCMs were observed in 77% of cases whereas subtentorial in 23%. Mean size of CCMs in the supra- and subtentorial area equaled 10.6±6.3 and 15.1±5.8 mm, respectively (p<0.05). Clinical symptoms occurred in 65.8% of patients, most frequently in patients with CCMs above 5 mm or with subtentorial lesions. All CCMs were hyperdense in CT images, with calcifications in 13.1%. In MRI, malformations showed diverse intensity of the central part with peripheral low-intensity rim of hemosiderine deposits in T2-weighted images. Conclusions: The clinical symptoms occur in most cases of CCMs. These patients require periodic follow-up MRI examinations, specifically those with haemorrhagic incidents or epileptic seizures, with large size or subtentorial CCMs.
Źródło:
Progress in Health Sciences; 2018, 8(2); 8-17
2083-1617
Pojawia się w:
Progress in Health Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Sacral insufficiency fracture following rectal cancer treatment – case report
Autorzy:
Pikula, A.
Pikula, T.S.
Pastuszak, M.
Powiązania:
https://bibliotekanauki.pl/articles/2098211.pdf
Data publikacji:
2020
Wydawca:
Instytut Medycyny Wsi
Tematy:
sacral fracture
rectal cancer
treatment
carcinoembryonic antigen
magnetic resonance imaging
radiotherapy
Opis:
Introduction and Objective. Locally advanced rectal cancers witha high risk of recurrence need multimodal treatment Rusing neoadiuvant preoperative chemoradiotherapy or preoperative radiotherapy. Both rectal cancer surgery and the additional chemoradiotherapy or radiotherapy may cause late sequelae. The aim of the study is to present a clinical situation in which a pelvic recurrence of rectal cancer has to be distinguished from therapy side effects. Insufficiency fracture (IF) is one of the therapy side-effects. It can cause pain and decrease mobility and it is a well-known late complication to pelvic radiotherapy, but can be misinterpreted as a local recurrence. Conclusions. It is extremely important to distinguish IF from metastases, which may require biopsies and initiation of potentially toxic treatments such as chemotherapy. MRI and CT scans are complementary modalities to make an accurate diagnosis of IF.
Źródło:
Journal of Pre-Clinical and Clinical Research; 2020, 14, 4; 120-122
1898-2395
Pojawia się w:
Journal of Pre-Clinical and Clinical Research
Dostawca treści:
Biblioteka Nauki
Artykuł
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