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    Tytuł:
    Hemodialysis dose and long-term COVID-19 outcomes – a retrospective cohort study
    Autorzy:
    Stepanova, Natalia
    Rysyev, Andriy
    Snisar, Lyudmyla
    Powiązania:
    https://bibliotekanauki.pl/articles/40416862.pdf
    Data publikacji:
    2024-03-30
    Wydawca:
    Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
    Tematy:
    dialysis dose
    hemodialysis
    hospitalization
    long COVID
    mortality
    Opis:
    Introduction and aim. Long-term outcomes of COVID-19 pose a global challenge, particularly impacting individuals with underlying health conditions, including those who have undergone hemodialysis (HD). The study aimed to investigate the relationship between preexisting dialysis dose, measured by single pool Kt/V (spKt/V), and long-term outcomes of COVID-19 in patients undergoing HD. Material and methods. Demographic, clinical, and laboratory parameters following COVID-19 recovery, and long-term outcomes, including the presence of COVID-19 sequelae, hospitalization, and all-cause mortality during a year after COVID-19 were retrospectively analyzed. Results. Out of the 195 patients included, there were 108 males (55.4%) and 87 females (44.6%), with a median age of 56 (44-63) years and a dialysis duration of 49 (31.3–85.2) months. Patients with spKt/V<1.4 had a significantly increased risk of long-term COVID-19 sequelae (HR 9.1, 95% CI: 3.4; 24.6), hospitalization (HR 7.6, 95% CI: 3.9; 14.6), and all-cause mortality (HR 8.5, 95% CI: 2.9; 25.8) within one year after COVID-19 recovery compared with those with spKt/V≥1.4. spKt/V cutoff point of ≤1.3 emerged as a significant risk factor for one-year hospitalization and mortality within our cohort. Conclusion. Suboptimal dialysis dose, as indicated by spKt/V < 1.4, is associated with adverse long-term COVID-19 outcomes in patients undergoing HD. Optimizing dialysis adequacy may mitigate these risks. Further research is needed to validate these findings and explore interventions to improve outcomes in this vulnerable population.
    Źródło:
    European Journal of Clinical and Experimental Medicine; 2024, 22, 1; 107-116
    2544-2406
    2544-1361
    Pojawia się w:
    European Journal of Clinical and Experimental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Association between brain fog, cardiac injury, and quality of life at work after hospitalization due to COVID-19
    Autorzy:
    Chatys-Bogacka, Żaneta
    Mazurkiewicz, Iwona
    Słowik, Joanna
    Słowik, Agnieszka
    Drabik, Leszek
    Wnuk, Marcin
    Powiązania:
    https://bibliotekanauki.pl/articles/29432123.pdf
    Data publikacji:
    2024-03-22
    Wydawca:
    Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
    Tematy:
    quality of life
    predictor
    troponin
    COVID-19
    brain fog
    long COVID
    Opis:
    Background To evaluate incidence and search for possible predictors of brain fog and quality of life at work (QoL-W) among low-to-moderate risk subjects previously hospitalized due to COVID-19. Material and Methods Participants aged ≥18 retrospectively reported 8 brain fog symptoms pre-COVID-19, at 0–4, 4–12 and >12 weeks post-infection via validated clinical questionnaire. The QoL-W was assessed with a 4-point Likert scale where 0, 1, 2, and 3 meant no, mild, moderate, and severe impairment in performing activities at work, respectively. Data on age, sex, comorbidities, and laboratory results (including first in-hospital high-sensitivity cardiac troponin I [hs-cTnI] measurement) were gathered. Results The study included 181 hospitalized subjects (age Me = 57 years), 37.02% women. Most had low disease severity (Modified Early Warning Score = 1, 77.90%) and low comorbidity (Charlson Comorbidity Index 0: 28.72%, 1–2: 34.09%), with no intensive care unit treatment needed. COVID-19 led to almost 3-fold increased brain fog symptoms, with incidence of 58.56%, 53.59%, and 49.17% within 4, 4–12, and >12 weeks, respectively (p < 0.001). First in-hospital hs-cTnI levels were 47.3% higher in participants who later presented with brain fog at median follow-up of 26.7 weeks since the diagnosis of the SARS-CoV-2 infection. Individuals who experienced at least one brain fog symptom at follow-up, had elevated hs-cTnI, less often presented with atrial fibrillation, and used anticoagulants during initial hospitalization due to COVID-19. The Hs-cTnI >11.90 ng/l predicted brain fog symptoms in multivariable model. COVID-19 was associated with 3.6‑fold, 3.0‑fold, and 2.4-fold QoL-W deterioration within 4, 4–12, and >12 weeks post-infection (p < 0.05). Subjects with QoL-W decline >12 weeks were younger, mostly women, had more brain fog symptoms, and higher platelet counts. Multivariable models with self-reported brain fog symptoms (responding coherently and recalling recent information), age, and sex exhibited good discriminatory power for QoL-W impairment (area under the receiver operating characteristic curve 0.846, 95% CI: 0.780–0.912). Conclusions This study highlighted that in non-high-risk subjects hospitalized during the first 2 pandemic’s waves: 1) brain fog was common, affecting nearly half of individuals, and impacting QoL-W >12 weeks after initial infection, 2) after 3 months of COVID-19 onset, the decline in QoL-W was primarily attributed to brain fog symptoms rather than demographic factors, health conditions, admission status, and laboratory findings, 3) components of brain fog, such as answering in an understandable way or recalling new information increased the likelihood of significantly lower QoL-W up to tenfold, 4) biochemical indicators, such as the first hs-cTnI level, might predict the risk of experiencing brain fog symptoms and indirectly decreased QoL-W >12 weeks after COVID-19 onset. Occupational medicine practitioners should pay particular attention to younger and female subjects after COVID-19 complaining of problems with answering questions in understandable way or recalling new information as they have an increased risk of QoL-W impairment.
    Źródło:
    Medycyna Pracy. Workers’ Health and Safety; 2024, 75, 1; 3-17
    0465-5893
    2353-1339
    Pojawia się w:
    Medycyna Pracy. Workers’ Health and Safety
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Neurostimulating complexes of physical exercises to neutralize long COVID
    Neurostymulujące zestawy ćwiczeń fizycznych w przeciwdziałaniu long COVID
    Autorzy:
    Postol, Olga
    Shchadilova, Irina
    Powiązania:
    https://bibliotekanauki.pl/articles/2056563.pdf
    Data publikacji:
    2022
    Wydawca:
    Akademia Bialska Nauk Stosowanych im. Jana Pawła II w Białej Podlaskiej
    Tematy:
    long COVID
    alternative therapy
    exercise
    students
    terapia niekonwencjonalna
    ćwiczenia
    studenci
    Źródło:
    Health Problems of Civilization; 2022, 16, 1; 3-4
    2353-6942
    2354-0265
    Pojawia się w:
    Health Problems of Civilization
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Quality of life of a patient with persistent complications after SARS-CoV-2 infection requiring urgent surgical intervention – endarterectomy with emergency angioplasty of an inflamed, bleeding Right Internal Carotid Artery (RICA) using the Trans-Carotid Artery Revascularization (TCAR)
    Autorzy:
    Hydzik, Adam
    Opławski, Maxymilian
    Trystuła, Mariusz
    Pąchalska, Maria
    Powiązania:
    https://bibliotekanauki.pl/articles/29519210.pdf
    Data publikacji:
    2023-07-17
    Wydawca:
    Fundacja Edukacji Medycznej, Promocji Zdrowia, Sztuki i Kultury Ars Medica
    Tematy:
    long COVID
    depression
    diabetes
    TIA
    CAS
    CEA
    SF-36
    emergency
    TCAR
    HRQOL
    Opis:
    SUMMARY The purpose of this study was to determine the quality of life of a patient with persistent complications of SARS-CoV-2 infection requiring urgens surgical intervention – endarterectomy with emergency angioplasty of an inflamed, bleeding Right Internal Carotid Artery (RICA) by direct access via Right Common Carotid Artery (RCCA), known as Transcarotid Artery Revascularization (TCAR). A patient in her 60s was infected with the SARS-CoV-2 virus and contracted COVID-19 in March 2022, as confirmed by RT PCR antigen test. The infection was followed by short- and long-term complications, many of which can be linked to COVID. These include significant weakness persisting for months after the illness, rapid weight loss of 25 kg, sleep disturbances, chronic fatigue, severe dizziness, onset of diabetes, decrease dimmunity with increased periodontal inflammation (including formation of a periapical abscess of a molar tooth) and secondary suppuration of the submandibular lymphnodes, one of which lying jacent to the right internal carotidartery (RICA). This accumulation of symptoms led the patient to seek medical and neuropsychological help. Test ingusing the Beck Depression Inventory (BDI) confirmed depression, with vegetative disorders being the most predominant. Eight months after undergoing COVID-19, the patient suffered a Transient Ischemic Attack (TIA). The accumulation of diseases (diabetes mellitus, stage III hypertension and TIA) had a dramatic impact on the patient's health, including life-threatening conditions.A vascular surgeon consulted the patient advised immediate surgical treatment: carotid endarterectomy. The urgency of the situation was exacerbated by bleeding during the operation from the operated, secondarily inflamed wall of the RICA (lying adjacent to the suppurated submandibular node). This prompted an emergency decision for an endovascular procedure: the implantation of a stent covered with water-proof material (peripheral stent graft). This was made by a direct access via puncture of the common carotid artery (RCCA) below the endarterectomy level (TCAR). The SF-36 questionnaire was chosen to measure health-related quality of life (HRQOL).The SF-36 results are presented in such a way that higher scores correspond to fewer complaints, indicating better health and higher quality of life. Before revascularization, the patient's HRQOL was found to be lower, which was related to the negative impact of long COVID, while after the procedure, the quality of life gradually improved in subsequent surveys. A significant difference was found in physical function, with a mean score of 66.0 (p<0.001) compared to a score of 94.9 (±9.4) for 100 age-matched health subjects. A similar result was found in the physical role (p < 0.001). The patient's overall quality of life score was 331.0 compared to a score of 578.0 (±111.9) for age-matched normal healthy people. Better quality of life in patients with long COVID is an important therapeutic goal that can be achieved through comprehensive, multispecialty treatment for both physical and psychological conditions.
    Źródło:
    Acta Neuropsychologica; 2023, 21(3); 259-278
    1730-7503
    2084-4298
    Pojawia się w:
    Acta Neuropsychologica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Neuropsychological consequences of COVID-19: current approach and clinical recommendations
    Autorzy:
    Treder-Rochna, Natalia
    Witkowska, Marta A.
    Powiązania:
    https://bibliotekanauki.pl/articles/29519204.pdf
    Data publikacji:
    2024-03-22
    Wydawca:
    Fundacja Edukacji Medycznej, Promocji Zdrowia, Sztuki i Kultury Ars Medica
    Tematy:
    elderly
    chronic pulmonary diseases
    cognitive dysfunction
    neurodegenerative diseases
    mental health
    emotional functioning
    brain fog
    global pandemic
    psychosocial factors
    neuropsychological diagnosis
    neuropsychological rehabilitation
    hypoxia
    infection of SARS-CoV-2
    NeuroCOVID 19
    long COVID
    Opis:
    Nearly two years into the pandemic, a large body of data has emerged on how COVID-19-positive patients function with the viral infection. It is now known that the virus targets the central nervous system(CNS). As a result, in addition to the expected common health complaints, patients display cognitive and emotional problems. Cognitive deficits should be expected particularly in patients who have arrived at an intensive care unit as a result of respiratory failure, in patients suffering from comorbid neurodegenerative diseases and respiratory conditions, as well as in the elderly. However, these may also occur in patients with moderate to mild symptoms as well as in those of a younger age. The cognitive impairment has an unknown profile. Given the hypothesised hippocampal vulnerability to the SARS-CoV-2 virus, one might expect particular difficulties with memory, attention, information processing, and executive functions. With varying neuropsychological and emotional problems, convalescents in trying to return to their social, family and professional life require professional psychological assistance. The role of neuropsychologists is here crucial. Indeed, many patients will require a detailed, multifaceted neuropsychological diagnosis that will form the basis for subsequent neuropsychological rehabilitation. An early detection of neuropsychological manifestations could modify the risk of subsequent irreversible impairment and further neurocognitive decline.
    Źródło:
    Acta Neuropsychologica; 2024, 22(1); 107-128
    1730-7503
    2084-4298
    Pojawia się w:
    Acta Neuropsychologica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-5 z 5

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