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Wyświetlanie 1-13 z 13
Tytuł:
Post-transplant Metabolic Syndrome (PTMS) after Liver Transplantation – Review of the Literature
Autorzy:
Kotarska, Katarzyna
Raszeja-Wyszomirska, Joanna
Powiązania:
https://bibliotekanauki.pl/articles/1054740.pdf
Data publikacji:
2015
Wydawca:
Uniwersytet Szczeciński. Wydawnictwo Naukowe Uniwersytetu Szczecińskiego
Tematy:
liver transplantation
metabolic syndrome
Opis:
Liver transplant provides a definitive therapeutic measure for patients with chronic and acute liver diseases. Apart from the improvement of overall health, an organ transplant entails several metabolic complications. They are multi-agent and depend, among others, on the function of organ being transplanted, adverse effects of immunosuppression being applied, organ complications induced by failure of the organ being transplanted, current treatment, concomitant diseases and consequences of the acute and chronic rejection processes. Improvements in surgical techniques, peritransplant intensive care, and immunosuppressive regimens have resulted in significant improvements in short-term survival. Focus has now shifted to address long-term outcomes of liver transplantation. Therefore, this paper presents the current review of literature referring to specificity of the prevalence of metabolic syndrome and its complications in patients after liver transplantation.
Źródło:
Central European Journal of Sport Sciences and Medicine; 2015, 11, 3; 29-37
2300-9705
2353-2807
Pojawia się w:
Central European Journal of Sport Sciences and Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
1000 Liver Transplantations at the Department of General, Transplant and Liver Surgery, Medical University of Warsaw - Analysis of Indications and Results
Autorzy:
Krawczyk, Marek
Grąt, Michał
Barski, Krzysztof
Ligocka, Joanna
Antczak, Arkadiusz
Kornasiewicz, Oskar
Skalski, Michał
Patkowski, Waldemar
Nyckowski, Paweł
Zieniewicz, Krzysztof
Grzelak, Ireneusz
Pawlak, Jacek
Alsharabi, Abdulsalam
Wróblewski, Tadeusz
Paluszkiewicz, Rafał
Najnigier, Bogusław
Dudek, Krzysztof
Remiszewski, Piotr
Smoter, Piotr
Grodzicki, Mariusz
Korba, Michał
Kotulski, Marcin
Cieślak, Bartosz
Kalinowski, Piotr
Gierej, Piotr
Frączek, Mariusz
Rdzanek, Łukasz
Stankiewicz, Rafał
Kobryń, Konrad
Nazarewski, Łukasz
Leonowicz, Dorota
Urban-Lechowicz, Magdalena
Skwarek, Anna
Giercuszkiewicz, Dorota
Paczkowska, Agata
Piwowarska, Jolanta
Gelo, Remigiusz
Andruszkiewicz, Paweł
Brudkowska, Anna
Andrzejewska, Renata
Niewiński, Grzegorz
Kilińska, Beata
Zarzycka, Aleksandra
Nowak, Robert
Kosiński, Cezary
Korta, Teresa
Ołdakowska-Jedynak, Urszula
Sańko-Resmer, Joanna
Foroncewicz, Bartosz
Ziółkowski, Jacek
Mucha, Krzysztof
Senatorski, Grzegorz
Pączek, Leszek
Habior, Andrzej
Lechowicz, Robert
Polański, Sławomir
Leowska, Elżbieta
Pacho, Ryszard
Andrzejewska, Małgorzata
Rowiński, Olgierd
Kozieł, Sławomir
Żurakowski, Jerzy
Ziarkiewicz-Wróblewska, Bogna
Górnicka, Barbara
Hevelke, Piotr
Michałowicz, Bogdan
Karwowski, Andrzej
Szczerbań, Jerzy
Powiązania:
https://bibliotekanauki.pl/articles/1396689.pdf
Data publikacji:
2012-06-01
Wydawca:
Index Copernicus International
Tematy:
liver transplantation
indications
results
mortality
Opis:
The aim of the study was to analyze indications and results of the first one thousand liver transplantations at Chair and Clinic of General, Transplantation and Liver Surgery, Medical University of Warsaw.Material and methods. Data from 1000 transplantations (944 patients) performed at Chair and Clinic of General, Transplantation and Liver Surgery between 1994 and 2011 were analyzed retrospectively. These included 943 first transplantations and 55 retransplantations and 2 re-retransplantations. Frequency of particular indications for first transplantation and retransplantations was established. Perioperative mortality was defined as death within 30 days after the transplantation. Kaplan-Meier survival analysis was used to estimate 5-year patient and graft survival.Results. The most common indications for first transplantation included: liver failure caused by hepatitis C infection (27.8%) and hepatitis B infection (18%) and alcoholic liver disease (17.7%). Early (< 6 months) and late (> 6 months) retransplantations were dominated by hepatic artery thrombosis (54.3%) and recurrence of the underlying disease (45%). Perioperative mortality rate was 8.9% for first transplantations and 34.5% for retransplantations. Five-year patient and graft survival rate was 74.3% and 71%, respectively, after first transplantations and 54.7% and 52.9%, respectively, after retransplantations.Conclusions. Development of liver transplantation program provided more than 1000 transplantations and excellent long-term results. Liver failure caused by hepatitis C and B infections remains the most common cause of liver transplantation and structure of other indications is consistent with European data.
Źródło:
Polish Journal of Surgery; 2012, 84, 6; 304-312
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Reoperations for intraabdominal bleeding following deceased donor liver transplantatio
Autorzy:
Figiel, Wojciech
Grąt, Michał
Wronka, Karolina
Patkowski, Waldemar
Krasnodębski, Maciej
Masior, Łukasz
Stypułkowski, Jan
Grąt, Karolina
Krawczyk, Marek
Powiązania:
https://bibliotekanauki.pl/articles/1393849.pdf
Data publikacji:
2016
Wydawca:
Index Copernicus International
Tematy:
liver transplantation
bleeding
reoperation
mortality
outcomes
Opis:
Intraabdominal hemorrhage remains one of the most frequent surgical complications after liver transplantation. The aim of the study was to evaluate risk factors for intraabdominal bleeding requiring reoperation and to assess the relevance of the reoperations with respect to short- and long-term outcomes following liver transplantation. Material and methods. Data of 603 liver transplantations performed in the Department of General, Transplant and Liver Surgery in the period between January 2011 and September 2014 were analyzed retrospectively. Study end-points comprised: reoperation due to bleeding and death during the first 90 postoperative days and between 90 postoperative day and third post-transplant year. Results. Reoperations for intraabdominal bleeding were performed after 45 out of 603 (7.5%) transplantations. Low pre-transplant hemoglobin was the only independent predictor of reoperation (p=0.002) with the cut-off of 11.3 g/dl. Postoperative 90-day mortality was significantly higher in patients undergoing reoperation as compared to the remaining patients (15.6% vs 5.6%, p=0.008). Post-transplant survival from 90 days to 3 years was non-significantly lower in patients after reoperation for bleeding (83.3%) as compared to the remaining patients (92.2%, p=0.096). Nevertheless, multivariable analyses did not reveal any significant negative impact of reoperations for bleeding on short-term mortality (p=0.589) and 3-year survival (p=0.079). Conclusions. Surgical interventions due to postoperative intraabdominal hemorrhage do not appear to affect short- and long-term outcomes following liver transplantation. Preoperative hemoglobin concentration over 11.3 g/dl is associated with decreased risk of this complication, yet the clinical relevance of this phenomenon is doubtful.
Źródło:
Polish Journal of Surgery; 2016, 88, 4; 196-201
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Quality of life and physical activity after liver transplantation. Literature review
Autorzy:
Stępień-Słodkowska, Marta
Niewiadomska, Monika
Kotarska, Katarzyna
Powiązania:
https://bibliotekanauki.pl/articles/1054800.pdf
Data publikacji:
2017
Wydawca:
Uniwersytet Szczeciński. Wydawnictwo Naukowe Uniwersytetu Szczecińskiego
Tematy:
quality of life
liver transplantation
physical activity
Opis:
Liver transplantation has become one of the most effective treatments for end-stage renal disease. For patients, however, the decision to have orthotopic liver transplantation (OLT) is often made in an effort to improve their quality of life and to reduce their risk of mortality and morbidity. Quality of life is an important aspect of therapy for transplant patients because this category reflects the subjective evaluation of one's own life in the physical, psychological and social dimensions. One of the means to achieve a better quality of life is not only good health, but also physical activity. Physical activity has been demonstrated to be of significance not only in the assessment of fitness levels but also could be of importance in long term recovery process after major surgical operations. The aim of this study was a review of literature showing the improved quality of life in patients after liver transplantation as well as the influence of physical activity on their physical health, mental health and quality of life after transplantation. Longitudinal data showed remarkable improvement of common domains of QOL comparing pre- and post-transplant items. Gender, occupation and regular physical activity have an influence on the quality of life after liver transplantation.
Źródło:
Central European Journal of Sport Sciences and Medicine; 2017, 17, 1; 51-60
2300-9705
2353-2807
Pojawia się w:
Central European Journal of Sport Sciences and Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Pathogenesis and clinical consequences of iron overload in chronic hepatitis C - impact of host and viral factors related to iron metabolism
Autorzy:
Sikorska, K.
Romanowski, T.
Bielawski, K.P.
Powiązania:
https://bibliotekanauki.pl/articles/80838.pdf
Data publikacji:
2011
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
antiviral therapy
chronic hepatitis C
clinical consequence
fibrosis
hepatocellular carcinoma
infection
interferon
iron metabolism
iron overload
liver cirrhosis
liver disease
liver transplantation
pathogenesis
ribavirin
virus replication
Źródło:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2011, 92, 1
0860-7796
Pojawia się w:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Prognostic value of perioperative assessment of plasma cardiac troponin I in patients undergoing liver transplantation
Autorzy:
Jankowski, Krzysztof
Trzebicki, Janusz
Bielecki, Maksymilian
Łągiewska, Beata
Kurnicka, Katarzyna
Koczaj-Bremer, Magdalena
Pacholczyk, Marek
Pruszczyk, Piotr
Powiązania:
https://bibliotekanauki.pl/articles/1038657.pdf
Data publikacji:
2017
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
cardiac troponin I
liver transplantation
surgery time
Opis:
Abstract. An elevation in plasma cardiac troponins is an indicator of increased perioperative risk in orthopaedic and vascular surgery, however, data on liver transplantation (LTx) are scarce. The aim of the study was to evaluate the prevalence of cardiac troponin I (cTnI) elevation in the perioperative period of LTx, and its potential relationship with 1-year mortality. Material and methods. Analysis included 79 patients with liver cirrhosis. During LTx all patients underwent hemodynamic measurements. cTnI level was determined before the operation, 24, 48 and 72 hours afterwards. One-year mortality was assessed. Results. 12.7% patients died, all during in-hospital period. cTnI level on day 1. was identified as the most promising marker of increased death risk with optimal cut-off value of 0.215 ng/mL (the sensitivity of 60.0%, specificity of 87.0%, positive predictive value of 40.0%, negative predictive value of 93.8%). The most important predictor of cTnI increase was the duration of the LTx procedure followed by amount of packed red blood cells transfused, basic stroke volume index, and cardiac output index. In conclusion: value of cTnI level assessed 24 hours post-surgery was a reliable predictor of death following LTx with optimal cut-off value of 0.215 ng/mL. The surgery time was the most important predictor of cTnI elevation.
Źródło:
Acta Biochimica Polonica; 2017, 64, 2; 331-337
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Mucormycosis in a patient with acute myeloblastic leukemia following liver transplantation for Wilson’s disease
Autorzy:
Łanocha, A.A.
Guzicka-Kazimierczak, R.
Zdziarska, B.
Wawrzynowicz-Syczewska, M.
Powiązania:
https://bibliotekanauki.pl/articles/2085182.pdf
Data publikacji:
2019
Wydawca:
Instytut Medycyny Wsi
Tematy:
Mucormycosis
acute myeloblastic leukemia
Willson’s disease
liver transplantation
Opis:
A case is presented of mucormycosis in a patient with acute myeloblastic leukemia following liver transplantation for Wilson’s disease. A 58-year-old female was admitted to the Department of Haematology with deterioration of her general condition, loss of appetite, tiredness and difficulty with mental contact for a few days. Blood and urine cultures for bacteria and fungus, galactomannan antigen were negative. Whole body computed tomography demonstrated bilateral hilar lymphadenopathy with necrotic lesions: splenomegaly with a hypodensive lesion 13 × 20 × 19 mm and lower pulmonary infiltrates suggested fungal etiology. Magnetic resonance imaging of the brain showed thickened meninges. Finally, mucormycosis was diagnosed. Treatment with amphotericin B lipid complex was started, resulting in an partial improvement of the general condition and decreased level of inflammatory markers. However, the patient’s condition continued to deteriorate, with sepsis etiology Escherichia coli, and despite the intensive managements she eventually died.
Źródło:
Annals of Agricultural and Environmental Medicine; 2019, 26, 4; 665-668
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Opieka pielęgniarska nad pacjentem z niewydolnością wątroby przeszczepionej, niezakwalifikowanym do retransplantacji - studium przypadku w oparciu o klasyfikację ICNP®
Nursing care of patient with liver transplant failure who was disqualified from retransplantation surgery – a case study based on ICNP®
Autorzy:
Ostrowska, Aleksandra
Sak-Dankosky, Natalia
Czarkowska-Piątek, Bożena
Powiązania:
https://bibliotekanauki.pl/articles/1182164.pdf
Data publikacji:
2019
Wydawca:
Państwowa Uczelnia Zawodowa we Włocławku
Tematy:
icnp
ostra niewydolność wątroby
pielęgniarstwo transplantologiczne
proces pielęgnowania
przeszczepienie wątroby
transplantologia
acute liver failure
liver transplantation
nursing process
transplant nursing
transplantology
Opis:
Wstęp. Życie pacjenta z niewydolnością wątroby w zaawansowanym stadium można uratować jedynie dzięki transplantacji. Istnieje jednak wiele przyczyn, z powodu których pacjenci mogą zostać do niej niezakwalifikowani. Opieka nad pacjentem, niezakwalifikowanym do transplantacji, wymaga szczególnego zaangażowania pielęgniarki we wszystkie biopsychospołeczne sfery życia pacjenta. Cel pracy. Celem pracy była identyfikacja problemów pielęgnacyjnych, określenie deficytu samoopieki oraz zaplanowanie opieki pielęgniarskiej nad pacjentem z niewydolnością wątroby przeszczepionej, niezakwalifikowanego do retransplantacji, przebywającego w szpitalu na oddziale transplantologii. Opis przypadku. Zaplanowano opiekę nad chorym z niewydolnością wątroby przeszczepionej w przebiegu przewlekłego odrzucania, chorującym także na przewlekłą chorobą nerek o niejasnej etiologii, u którego występują również zaburzenia świadomości, agresja, obniżony nastrój i strach przed śmiercią. W planowaniu opieki zastosowano Międzynarodową Klasyfikację Praktyki Pielęgniarskiej ICNP®. Dyskusja. Plan opieki został opracowany według teorii Virginii Henderson. Pacjent wymagał pomocy w czynnościach dnia codziennego oraz wsparcia psychicznego, szczególnie pomocy w zrozumieniu jego obecnej sytuacji i radzeniu sobie z uczuciem samotności. Wnioski. Zastosowanie Międzynarodowej Klasyfikacji Praktyki Pielęgniarskiej ICNP® w planowaniu opieki pielęgniarskiej nad pacjentem z niewydolnością wątroby przeszczepionej pozwala na polepszenie jakości opieki na pacjentem i umożliwiona analizę wiedzy o opiece nad pacjentem w kontekście międzynarodowym.
Introduction. Life of patient suffering from an advanced-stage liver failure can be saved only by transplantation surgery. Many patients, however, do not qualify for this type of treatment for a variety of reasons. Caring for a patient who was disqualified from the surgery is challenging and requires focusing on all biopsychosocial aspects of patient’s life. Aim of the study. The aims of this study were to identify nursing problems, to estimate the self-care deficits, and to plan nursing care for a patient with a liver transplant failure currently hospitalized in a transplantology unit. Case study. Nursing care of patient with a liver graft failure in the course of chronic graft rejection was carefully planned. The patient was also diagnosed with a chronic kidney disease of unknown aetiology. Moreover, the patient suffered from a fluctuating consciousness and mood depression, manifest aggressive behaviours and the fear of death. To plan patient’s care the International Classification for Nursing Practice ICNP® was used. Discussion. Nursing care was planned in accordance with Virginia Henderson’s theory which emphasizes the Maslow hierarchy of needs Patient required help with daily activities and needed psychological support, especially in coping with his current situation and dealing with the feeling of loneliness. Conclusions. Applying the International Classification for Nursing Practice ICNP® in the planning of nursing care for a patient with liver graft failure enables the improvement of the patient's quality of life and the awareness of nursing care in the international area.
Źródło:
Innowacje w Pielęgniarstwie i Naukach o Zdrowiu; 2019, 4, 4; 78-114
2451-1846
Pojawia się w:
Innowacje w Pielęgniarstwie i Naukach o Zdrowiu
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Lifestyle risk factors of non-communicable diseases among patients after liver transplantation – a pilot study
Autorzy:
Jagielska, Anna
Jankowski, Krzysztof
Okręglicka, Katarzyna
Skupin, Paulina
Kozłowska, Aleksandra
Durlik, Magdalena
Pruszczyk, Piotr
Nitsch - Osuch, Aneta
Tronina, Olga
Powiązania:
https://bibliotekanauki.pl/articles/553082.pdf
Data publikacji:
2017
Wydawca:
Stowarzyszenie Przyjaciół Medycyny Rodzinnej i Lekarzy Rodzinnych
Tematy:
ife style
liver transplantation
risk of non-communicable diseases.
Źródło:
Family Medicine & Primary Care Review; 2017, 3; 214-220
1734-3402
Pojawia się w:
Family Medicine & Primary Care Review
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Evolution Of The Results Of 1500 Liver Transplantations Performed In The Department Of General, Transplant And Liver Surgery Medical University Of Warsaw
Autorzy:
Krawczyk, Marek
Grąt, Michał
Grąt, Karolina
Wronka, Karolina
Krasnodębski, Maciej
Stypułkowski, Jan
Masior, Łukasz
Hołówko, Wacław
Ligocka, Joanna
Nyckowski, Paweł
Wróblewski, Tadeusz
Paluszkiewicz, Rafał
Patkowski, Waldemar
Zieniewicz, Krzysztof
Pączek, Leszek
Milkiewicz, Piotr
Ołdakowska-Jedynak, Urszula
Najnigier, Bogusław
Dudek, Krzysztof
Remiszewski, Piotr
Grzelak, Ireneusz
Kornasiewicz, Oskar
Kotulski, Marcin
Smoter, Piotr
Grodzicki, Mariusz
Korba, Michał
Kalinowski, Piotr
Skalski, Michał
Zając, Krzysztof
Stankiewicz, Rafał
Przybysz, Marta
Cieślak, Bartosz
Nazarewski, Łukasz
Nowosad, Małgorzata
Kobryń, Konrad
Wasilewicz, Michał
Raszeja-Wyszomirska, Joanna
Piwowarska, Jolanta
Giercuszkiewicz, Dorota
Sańko-Resmer, Joanna
Rejowski, Sławomir
Szydłowska-Jakimiuk, Monika
Górnicka, Barbara
Wróblewska-Ziarkiewicz, Bogna
Mazurkiewicz, Michał
Niewiński, Grzegorz
Pawlak, Jacek
Pacho, Ryszard
Powiązania:
https://bibliotekanauki.pl/articles/1395614.pdf
Data publikacji:
2015-05-01
Wydawca:
Index Copernicus International
Tematy:
liver transplantation
survival
outcomes
donors
center experience
center volume
Opis:
Liver transplantation is a well-established treatment of patients with end-stage liver disease and selected liver tumors. Remarkable progress has been made over the last years concerning nearly all of its aspects. The aim of this study was to evaluate the evolution of long-term outcomes after liver transplantations performed in the Department of General, Transplant and Liver Surgery (Medical University of Warsaw). Material and methods. Data of 1500 liver transplantations performed between 1989 and 2014 were retrospectively analyzed. Transplantations were divided into 3 groups: group 1 including first 500 operations, group 2 including subsequent 500, and group 3 comprising the most recent 500. Five year overall and graft survival were set as outcome measures. Results. Increased number of transplantations performed at the site was associated with increased age of the recipients (p<0.001) and donors (p<0.001), increased rate of male recipients (p<0.001), and increased rate of piggyback operations (p<0.001), and decreased MELD (p<0.001), as well as decreased blood (p=0.006) and plasma (p<0.001) transfusions. Overall survival was 71.6% at 5 years in group 1, 74.5% at 5 years in group 2, and 85% at 2.9 years in group 3 (p=0.008). Improvement of overall survival was particularly observed for primary transplantations (p=0.004). Increased graft survival rates did not reach the level of significance (p=0.136). Conclusions. Long-term outcomes after liver transplantations performed in the Department of General, Transplant and Liver Surgery are comparable to those achieved in the largest transplant centers worldwide and are continuously improving despite increasing recipient age and wider utilization of organs procured from older donors.
Źródło:
Polish Journal of Surgery; 2015, 87, 5; 221-230
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Reprinted with permission of editor-in-chief of Annals of Surgery: Annals of Surgery: Vol. 266, nr 5, November 2017; 703 - 705: Modern Surgeons: Still Masters of Their Trade or Just Operators of Medical Equipment?
Autorzy:
Krawczyk, Marek
Powiązania:
https://bibliotekanauki.pl/articles/1392874.pdf
Data publikacji:
2018
Wydawca:
Index Copernicus International
Tematy:
vascular surgery
cholecystectomy
ultrasonography
bile ducts
liver transplantation
pancreas
laparoscopy
Opis:
My surgical education began at a time when Poland formed part of the communist bloc and was isolated from the world, or in today’s Terms – it remained behind the Iron Curtain. This was true of all areas of life, including medicine. When after 40 years of work, I look back at my professional career; I wonder whether I owe my proficiency in surgery to my experience and dexterity or, like many others, to technological progress. Two of the great Polish surgeons were my mentors and teachers. Professor Zdzisław Łapiński was the one I met first. He was a manual genius and an unusual operational strategist. Granted, he had one character defect, but nobody’s perfect after all. In 1975, I defended my dissertation. I was convinced that I should continue my education at a center abroad, preferably within a postdoctoral scholarship. Professor Łapiński wanted me to learn everything about surgery from him. I decided otherwise, and in 1978 with his tacit agreement, I obtained a Humboldt Fellowship and went to Heidelberg, to the department headed by none other than Professor Fritz Linder.1 I started my research for the habilitation thesis at the Experimentelle Chirurgie Abteilung of his Department.
Źródło:
Polish Journal of Surgery; 2018, 90, 2; 1-4
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Short and Long-Term Outcomes After Primary Liver Transplantation in Elderly Patients
Autorzy:
Grąt, Michał
Kornasiewicz, Oskar
Grąt, Karolina
Antczak, Arkadiusz
Ligocka, Joanna
Hołówko, Wacław
Wronka, Karolina Maria
Kobryń, Konrad
Skalski, Michał
Pączek, Leszek
Krawczyk, Marek
Powiązania:
https://bibliotekanauki.pl/articles/1396438.pdf
Data publikacji:
2013-10-01
Wydawca:
Index Copernicus International
Tematy:
liver transplantation
outcomes
elderly patients
recipient age
malignancies
donor age
Opis:
The number of elderly patients undergoing liver transplantation (LT) is increasing worldwide. The aim of the study was to evaluate the impact of recipient age exceeding 60 years on early and long-term outcomes after LT. Material and methods. This study comprised data of 786 patients after primary LT performed at a single center between January 2005 and October 2012. Patients over and under 60 years of age were compared with respect to baseline characteristics and outcomes: postoperative mortality (90-day) and 5-year patient (PS) and graft (GS) survival. Associations between recipient age exceeding 60 years and LT results were assessed in multiple Cox regression models. Results. Recipients older than 60 years (n=107; 13.6%) were characterized by more frequent hepatitis C virus infections (p<0.001), malignancies (p<0.001), and cardiovascular comorbidities (p<0.001); less frequent primary sclerosing cholangitis (p=0.002) and Roux-en-Y hepaticojejunostomy (p<0.001); lower Model for End-stage Liver Disease (MELD; p=0.043); and increased donor age (p=0.012). Fiveyear PS of older and younger recipients was 72.7% and 80.6% (p=0.538), while the corresponding rates of GS were 70.3% and 77.5% (p=0.548), respectively. Recipient age exceeding 60 years was not significantly associated with postoperative mortality (p=0.215), PS (p=0.525) and GS (p=0.572) in multivariate analyses. The list of independent predictors comprised MELD (p<0.001) for postoperative mortality; malignancies (p=0.003) and MELD (p<0.001) for PS; and malignancies (p=0.003), MELD (p<0.001) and donor age (p=0.017) for GS. Conclusions. Despite major differences between elderly and young patients, chronological age exceeding 60 years alone should not be considered as a contraindication for LT.
Źródło:
Polish Journal of Surgery; 2013, 85, 10; 581-588
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Standardy badań ultrasonograficznych Polskiego Towarzystwa Ultrasonograficznego. Ocena układu wrotnego i naczyń wątroby
Standards of the Polish Ultrasound Society. Ultrasound examination of the portal system and hepatic vessels
Autorzy:
Lechowicz, Robert
Elwertowski, Michał
Powiązania:
https://bibliotekanauki.pl/articles/1053515.pdf
Data publikacji:
2015
Wydawca:
Medical Communications
Tematy:
Doppler ultrasound
hepatic veins
liver transplantation
portal hypertension
portal vein
nadciśnienie wrotne
przeszczepienie wątroby
ultrasonografia dopplerowska
żyła wrotna
żyły wątrobowe
Opis:
Increased incidence of liver diseases, the development of liver surgery and other invasive methods for managing portal hypertension, plus an increasing number of liver transplant procedures pose more and more new challenges for ultrasonography. Ultrasonography, being an effective and clinically verified modality, has been used for several decades for diagnosing diseases of the liver, its vessels and portal hypertension. It is used for both initial and specialist diagnosis (performed in reference centers). The diagnostic value of ultrasonography largely depends on the knowledge of anatomy, physiology, pathophysiology and clinical aspects as well as on the mastering of the scanning technique. In the hands of an experienced physician, it is an accurate and highly effective diagnostic tool; it is of little use otherwise. The paper presents elements of anatomy, physiology and pathophysiology which make the portal system exceptional and the knowledge of which is crucial and indispensable for a correct examination and, above all, for the correct interpretation of results. The authors also present requirements regarding the equipment. Moreover, various technical aspects of the examination are presented and the normal morphological picture and hemodynamic parameters of healthy individuals are described. The authors discuss the most common clinical situations and rare cases during ultrasound examinations. The paper is based on the experience of the author who works in the largest center of liver diseases in Poland, and on the current literature.
Wzrost zachorowań na choroby wątroby oraz rozwój chirurgii wątroby i innych inwazyjnych metod leczenia nadciśnienia wrotnego, a także zwiększająca się liczba zabiegów transplantacji wątroby wyznaczają wciąż nowe wyzwania dla ultrasonografii. Ultrasonografia, jako skuteczna i sprawdzona klinicznie metoda, stosowana jest od kilku dekad w diagnostyce chorób wątroby, jej naczyń i nadciśnienia wrotnego. Wykorzystywana jest zarówno na poziomie diagnostyki wstępnej, jak i specjalistycznej – wykonywanej w ośrodkach referencyjnych. Wartość diagnostyczna ultrasonografii w dużym stopniu zależy od znajomości anatomii, fizjologii, patofizjologii i aspektów klinicznych, a także stopnia opanowania techniki badania. W rękach doświadczonego lekarza metoda ta jest precyzyjnym i bardzo skutecznym narzędziem diagnostycznym, w przeciwnym razie jest bezużyteczna. W opracowaniu omówiono podstawowe elementy anatomii, fizjologii i patofizjologii, które stanowią o wyjątkowości układu wrotnego, a których znajomość jest kluczowa i niezbędna dla prawidłowego wykonania badania, a przede wszystkim właściwej interpretacji wyników. Przedstawiono wymagania dotyczące zaawansowania wykorzystywanej aparatury. Omówiono różne techniczne aspekty badania oraz prawidłowy obraz morfologiczny i parametry hemodynamiczne u osób zdrowych, a także najczęstsze sytuacje kliniczne i związane z nimi odchylenia od norm w wykonywanych badaniach. Prezentowana praca oparta jest na kilkunastoletnim doświadczeniu autora pracującego w największym ośrodku chirurgii wątroby w Polsce oraz na podstawie aktualnego piśmiennictwa.
Źródło:
Journal of Ultrasonography; 2015, 15, 61; 208-226
2451-070X
Pojawia się w:
Journal of Ultrasonography
Dostawca treści:
Biblioteka Nauki
Artykuł
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