Autor: Kwaśniewska, J. - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: Aktualne mozliwosci stosowania lekow przeciwgrzybiczych w niektorych chorobach skory
Autorzy:: Choczaj-Kukula, A.
Kwasniewska, J.
Powiązania:: https://bibliotekanauki.pl/articles/838759.pdf
Data publikacji:: 2004
Wydawca:: Polskie Towarzystwo Parazytologiczne
Tematy:: choroby skory
grzybica skory
leki przeciwgrzybicze
stosowanie
Źródło:: Annals of Parasitology; 2004, 50, 2; 125-133
0043-5163
Pojawia się w:: Annals of Parasitology
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 2.

Tytuł:: Wrazliwosc na mikonazol i itrakonazol szczepow grzybow z rodzaju Candida wyodrebnionych od pacjentow hospitalizowanych i leczonych w trybie ambulatoryjnym
Susceptibility to miconazole and itraconazole of Candida strains isolated from hospitalized and outpatient clinic patients
Autorzy:: Kurnatowska, A.K.
Kwasniewska, J.
Powiązania:: https://bibliotekanauki.pl/articles/840111.pdf
Data publikacji:: 2009
Wydawca:: Polskie Towarzystwo Parazytologiczne
Tematy:: mikonazol
wrazliwosc na leki
itrakonazol
Candida
parazytologia lekarska
leczenie szpitalne
pacjenci
leki przeciwgrzybicze
szczepy grzybow
leczenie ambulatoryjne
grzybice
Źródło:: Annals of Parasitology; 2009, 55, 4; 415-423
0043-5163
Pojawia się w:: Annals of Parasitology
Dostawca treści:: Biblioteka Nauki

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Tytuł:: Wrażliwość na mikonazol i itrakonazol szczepów grzybów z rodzaju Candida wyodrębnionych od pacjentów hospitalizowanych i leczonych w trybie ambulatoryjnym
Susceptibility to miconazole and itraconazole of Candida strains isolated from hospitalized and outpatient clinic patients
Autorzy:: Kurnatowska, A.K.
Kwaśniewska, J.
Powiązania:: https://bibliotekanauki.pl/articles/2143561.pdf
Data publikacji:: 2009
Wydawca:: Polskie Towarzystwo Parazytologiczne
Tematy:: mikonazol
wrazliwosc na leki
itrakonazol
Candida
parazytologia lekarska
leczenie szpitalne
pacjenci
leki przeciwgrzybicze
szczepy grzybow
leczenie ambulatoryjne
grzybice
Opis:: It is known that fungi representing different genera and species can cause organ-limited or systemic infections after disrupting of the natural defense mechanisms in a human organism. The treatment of mycoses still encounters considerable difficulties. Therefore, in vitro assessment of the susceptibility of fungal strains to the antifungal agents now in use and to new drugs is needed more urgently than ever before. It should be emphasized that we treat the fungal susceptibility to antifungal drugs as a quantitative feature of the strain examined. The aim of the presently reported study was the evaluation of the antimycotic action of two azole compounds – miconazole and itraconazole (Janssen) against 205 Candida strains isolated from the various biological specimens of two groups of patients – hospitalized (group 1) and examined in outpatient clinic (group 2); differentiation of species and codes of these strains; analysis of dose-response curves and parameters of polygons of the azoles minimal inhibitory concentrations (MIC). The susceptibility to miconazole and itraconazole was estimated with the agar diffusion test on 3% Sabouraud’s agar – the method developed in our laboratory, using several different concentrations of the drug, which made the plotting of dose-response curves possible. The lowest concentration inhibiting the growth of fungal strain (MIC) was calculated using a transformed equation of rectilinear regression according to Kadłubowski. Species and fungal codes of isolated strains were evaluated according to the guidelines worked out in our department with the use of different media and biochemical tests (bioMérieux). Among 89 strains isolated from the hospitalized patients, six species of the genus Candida genus were found; one strain belonged to Trichosporon cutaneum species. The most frequently encountered species was Candida albicans (73%), which significantly dominated over C. tropicalis, C. parapsilosis, C. glabrata, C. lipolytica and C. famata. All strains from the second group of patients belonged to C. albicans species. In all C. albicans strains from both groups of patients, the most frequent assimilation code (2576174) was found. The miconazole MIC values for Candida strains isolated from the group 1 were characterized by a wide range of variation, from 0.0247mg/l to 6.826 mg/l, from group 2 – 0.0277 to 0.719 mg/l. The itraconazole MIC values were 0.011 to 2.813 mg/l, and 0.0103 to 0.718 mg/l, respectively. The analysis of mean values (x) of miconazole and itraconazole MICs and other parameters allowed us to find that the strains isolated from the patients of group 1 were significantly less susceptible to both drugs in comparison with the strains of the group 2 patients. Also, C. albicans strains from this group of patients had a significantly lower (x) MIC in comparison to the mean values for the most of Candida species isolated from the hospitalized patients (P<0.001). In conclusion, we have found that the most Candida strains from both groups of patients were susceptible to the examined antifungal agents. The strains isolated from the outpatient clinic patients were generally more susceptible especially to itraconazole in comparison with strains from hospitalized patients.
Źródło:: Wiadomości Parazytologiczne; 2009, 55, 4; 415-423
0043-5163
Pojawia się w:: Wiadomości Parazytologiczne
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 4.

Tytuł:: Aktualne możliwości stosowania leków przeciwgrzybiczych w niektórych chorobach skóry
Current possibilities of using antimycotic drugs in the treatment of various skin disorders.
Autorzy:: Choczaj-Kukuła, A.
Kwaśniewska, J.
Powiązania:: https://bibliotekanauki.pl/articles/2146442.pdf
Data publikacji:: 2004
Wydawca:: Polskie Towarzystwo Parazytologiczne
Tematy:: choroby skory
grzybica skory
leki przeciwgrzybicze
stosowanie
Opis:: The purpose of this article is to review the literature data on the therapeutic protocols and the results of using some antimycotics in different skin diseases. In addition to the antimycotic action, particular antifungal drugs such as itraconazole, ketoconazole and terbinafine exhibit anti-inflammatory activity by inhibiting the synthesis of 5-lipooxygenase metabolites. As these metabolites are involved in a number of inflammatory and immunoreactive processes the dual action of the drugs may be suitably exploited in the treatment of some skin diseases which are otherwise difficult to cure. Another rationale for the use of antimycotics in certain skin disorders is their action against Malassezia. It has been recently demonstrated that Malassezia, present as a commensal in the epidermis, may play an important role in inducing certain inflammatory processes by stimulating cytokine production by keratinocytes. The antimycotics proved to be useful in the therapy of the following skin conditions: seborrheic dermatitis, Malassezia folliculitis, perioral dermatitis and papulopustular rosacea, as well as adult atopic dermatitis. The use of antimycotic drugs in amicrobial palmoplantar pustulosis and sebopsoriasis remains controversial. These medications are also an alternative in the treatment of leishmaniosis.
Źródło:: Wiadomości Parazytologiczne; 2004, 50, 2; 125-133
0043-5163
Pojawia się w:: Wiadomości Parazytologiczne
Dostawca treści:: Biblioteka Nauki

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