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Wyszukujesz frazę "larynx cancer" wg kryterium: Temat

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    Wyświetlanie 1-2 z 2
    Tytuł:
    Occupational aetiologies of laryngeal cancer: is there a difference in comparison to (hypo) pharyngeal cancer?
    Autorzy:
    DeJonckere, Philippe H
    Moerman, Mieke
    Cantarella, Giovanna
    Crevier-Buchman, Lise
    Powiązania:
    https://bibliotekanauki.pl/articles/1401523.pdf
    Data publikacji:
    2016
    Wydawca:
    Index Copernicus International
    Tematy:
    larynx
    cancer
    occupation
    risk
    hypopharynx
    Opis:
    Introduction: The two major recognized risk factors for laryngeal cancer are tobacco and alcohol consumption. However, according to WHO and IARC, occupational factors are probably underestimated. Confirmed/highly probable occupational carcinogens related to laryngeal cancer include asbestos and strong organic acid mists. Probable carcinogens are cement, polycyclic aromatic hydrocarbons (PAH) and wood dust. Suspected carcinogens are organic solvents, formaldehyde, coal/silica dust, leather dust and cotton dust. An important problem of epidemiological studies appears to be the lack of differentiation between laryngeal and hypopharyngeal (squamous cell) carcinomas. Material and Methods: For the purposes of this study, a database of 164 well-documented cases of laryngeal and hypopharyngeal cancers was created by collecting data from 4 centres in Belgium, Italy and France. In order to identify confirmed, probable and suspected carcinogenic risks, jobs and exposures over the whole career of the patients were exhaustively identified and mapped. Confounding factors were taken in account. Results: In general, occupational exposure to known or suspected carcinogens is significantly higher in laryngeal than in hypopharyngeal carcinomas. As regards the exposed subjects, the global occupational exposure profiles differ significantly (10 categories). Asbestos and acid mist exposures are significantly more important in laryngeal carcinoma. Coal/silica dust exposure is significantly more important in pharyngeal carcinoma..
    Źródło:
    Polski Przegląd Otorynolaryngologiczny; 2016, 5, 4; 1-5
    2084-5308
    2300-7338
    Pojawia się w:
    Polski Przegląd Otorynolaryngologiczny
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The predictive value of videostroboscopy in the assessment of premalignant lesions and early glottis cancers
    Autorzy:
    Rzepakowska, Anna
    Sielska-Badurek, Ewelina
    Osuch-Wójcikiewicz, Ewa
    Sobol, Maria
    Niemczyk, Kazimierz
    Powiązania:
    https://bibliotekanauki.pl/articles/1398516.pdf
    Data publikacji:
    2017
    Wydawca:
    Index Copernicus International
    Tematy:
    laryngovideostroboscopy
    precancerous lesions
    larynx
    glottis
    early glottic cancer
    Opis:
    Objective: To assess the sensitivity and specificity of larngovideostroboscopy (LVS) in the diagnosis of precancerous and malignant lesions of the vocal folds. Material and methods: In 175 patients (128 men and 47 women), aged 19-88 years, mean age 61.5, who were admitted to the clinic with diagnosed premalignant conditions of vocal fold mucosa (leukoplakia, chronic hypertrophic inflammatory lesions) and thickening or tumor on the vocal fold, there was performed LVS before the laryngeal microsurgery. The LVS study included: localization of the leasion, movement of the vocal folds, mucosal wave, shape of glottis clousure, amplitude and symmetry of vocal fold vibration. In the evaluation, a point scale was applied for the individual functional parameters. The scale ranged from 0 to 14. Patients with impaired vocal fold motion or absent mucosal wave were positive on LVS for malignant lesions. Those with limitted mucosal wave were positive on LVS for dysplastic lesions. The results were compared with the final histopathological examination and the sensitivity, specificity, accuracy, positive (PPV) and negative (NPV) predictive value were calculated. Results: On the basis of histopathological examination, benign lesions (normal or inflammatory mucosa) accounted for 20% of diagnoses, hypertrophy and parakeratosis for 28%, low and middle grade dysplasia accounted for 10% and malignant lesions (high-grade dysplasia, pre-invasive cancer, Invasive cancer) was diagnosed in 42% of patients. The overall mean score for LVS was 4.5 and 8.0, respectively for benign and malignant lesions. Sensitivity, specificity, accuracy, PPV and NPV of LVS in detecting malignant lesions were respectively - 95.6%, 23.8%, 61.1%, 57.6% and 83.3% and in detecting both premalignant and malignant lesions were respectively – 90.7%, 31.4%, 78.9%, 84.1% and 45.8%. Conclusions: Because of the high sensitivity of LVS in detecting precancerous and malignant lesions, this method is a very good tool for screening of pathology within the larynx.
    Źródło:
    Polish Journal of Otolaryngology; 2017, 71, 4; 14-18
    0030-6657
    2300-8423
    Pojawia się w:
    Polish Journal of Otolaryngology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-2 z 2

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