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Wyświetlanie 1-4 z 4
Tytuł:
Relationship with peers of young school-aged children with type 1 diabetes
Autorzy:
Ledwon, E.
Szlenk-Czyczerska, E.
Gawlik, M.
Powiązania:
https://bibliotekanauki.pl/articles/1769.pdf
Data publikacji:
2018
Wydawca:
Uniwersytet Opolski. Instytut Nauk o Zdrowiu
Tematy:
child
school child
human development
human disease
diabetes mellitus type 1
parent
Opis:
Background: Functioning in a peer group plays an important role in child development. Building self-esteem of children depends on many factors such as physical health, self-evaluation of their physical performance, academic achievement, social support, family relationships, as well as relationships with peers and teachers. Importance of contacts with peers increases during school-age. At this time children are not able to reject the opinion of other people and subject their behaviour completely to the expectations of their peers. When the need for emotional contact is not satisfied, the complex of being different appears. Isolation within group causes a sense of inferiority, the child becomes passive and resigned. Children, who are chronically ill, rejected or isolated often follow negative emotions in their actions, they become aggressive towards other children or do not want to continue learning. Often the decision about an individual teaching plan results in further isolation of the child. The child’s position in the peer group affects the developing personality, self-confidence and self-esteem. Aim of the study: The aim of the study was to determine the interpersonal relationships of young school-aged children with type 1 diabetes in their peer groups. Material and methods: The study was conducted on children with type 1 diabetes and their parents, who are supervised by Clinic of Diabetes, Regional Medical Center in Opole. The research tool used in both groups was a questionnaire consisting of open and closed questions elaborated by the authors of this study. Results: 73% (41) of evaluated children declared that diabetes does not hinder their performance at school. 93% (55) children claimed that they do not hide their condition from their peers. In addition, 61% (34) talk about their illness with their peers and 69% (38) of them can count on their peers’ help in self-control of diabetes. 71.9% (46) of parents of children with type 1 diabetes allow their children to participate in school trips and 68.8% (44) to participate in school competitions. Conclusions: In most children, diabetes does not affect children’s performance at school. They participate in classes, are accepted and liked in their peer group. Chronically ill children should be able to participate in all types of activities as much as their healthy peers. It seems necessary to continue studies on performance of young school-aged children with type 1 diabetes in their peer group.
Źródło:
Medical Science Pulse; 2018, 12, 2
2544-1558
2544-1620
Pojawia się w:
Medical Science Pulse
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Health outcomes of vitamin D. Part II. Role in prevention of diseases
Autorzy:
Wranicz, J.
Szostak-Wegierek, D.
Powiązania:
https://bibliotekanauki.pl/articles/871663.pdf
Data publikacji:
2014
Wydawca:
Narodowy Instytut Zdrowia Publicznego. Państwowy Zakład Higieny
Tematy:
health outcome
vitamin D
prevention
human disease
diabetes mellitus
vitamin deficiency
cancer
cardiovascular disease
muscle physiology
Opis:
Apart from the classic role of vitamin D, its hormonal active form, calcitriol is also characterized by pleiotropic effects on various organs and tissues. For the last several years, many researchers have shown an association between deficiency of vitamin D and the risk of type 2 diabetes mellitus (T2DM). Recent investigations suggested the need of vitamin D supplementation in T2DM prevention. It was shown that vitamin D deficiency decreases insulin secretion. It was also observed that proper vitamin D supplementation may improve the ability of the cells of the islets of Langerhans to synthesize many proteins de novo and to convert proinsulin to insulin. Apart from regulating bone metabolism and also calcium and phosphate homeostasis, 1,25(OH)2D3 exerts antiproliferative and pro-differentiating effects on a wide variety of cell types. It also induces apoptosis of cancer cells and slows their proliferation. In a number of major studies the relationship between low vitamin D levels and increased risk of various cancers was observed. It concerns colorectal, lung, prostate, breast and ovarian cancer. It was observed that in patients with low serum vitamin D concentrations such disorders as ischemic heart disease, heart attack, stroke, cardiac arrhythmia, and hypertension were more frequent and mortality was significantly higher. These results led the researchers to consider vitamin D deficiency as a potential risk factor for cardiovascular diseases. The possible mechanism in the pathogenesis of cardiovascular diseases that may be related to low levels of vitamin D, is its adverse effect on the renin-angiotensin-aldosterone system (RAAS). Calcitriol is also an important determinant of muscle cell proliferation and differentiation, as well as inhibition of apoptosis. Vitamin D is synthesized in the skin. However, there are only a few food products that are rich in vitamin D3, e.g.: fish oils, fish and fortified-products, such as dairy products and margarines. Individuals who are vulnerable to vitamin D deficiency should be supplemented.
Poza klasyczną rolą witaminy D, jej hormonalna postać – kalcytriol wykazuje plejotropowe działanie na różne tkanki i narządy w organizmie. W ciągu ostatnich lat, wielu badaczy wykazało związek pomiędzy niedoborem witaminy D a ryzykiem wystąpienia cukrzycy typu 2 (T2DM). Wyniki badań sugerują potrzebę jej suplementacji w profilaktyce T2DM. Udowodniono związek między niedoborem witaminy D a upośledzonym wydzielaniem insuliny. Zaobserwowano również, że prawidłowa jej suplementacja poprawia zdolność komórek wysp Langerhansa do syntezy de novo wielu białek oraz przekształcania proinsuliny w insulinę. Poza regulowaniem metabolizmu kości i utrzymaniem homeostazy wapniowo-fosforowej, 1,25(OH)2D3 reguluje procesy proliferacji i różnicowania różnych komórek. Ponadto indukuje apoptozę komórek nowotworowych i zwalnia tempo ich proliferacji. W wielu badaniach zaobserwowano związek pomiędzy niskim poziomem witaminy D a zwiększonym ryzykiem wystąpienia różnych nowotworów. Dotyczyło to raka jelita grubego, płuc, prostaty, piersi i jajników. U pacjentów z niskimi stężeniami witaminy D w surowicy zaobserwowano częstsze występowanie schorzeń takich jak choroba niedokrwienna serca, zawał serca, udar mózgu, zaburzenia rytmu serca, nadciśnienie tętnicze oraz wyższą umieralność. Wyniki tych badań skłoniły do uznania niedoboru witaminy D za potencjalny czynnik ryzyka rozwoju chorób sercowo-naczyniowych. Możliwym mechanizmem w ich patogenezie, mogącym tłumaczyć omawiane zjawisko, jest wpływ witaminy D na układ renina-angiotensyna-aldosteron (RAAS). Kalcytriol jest także ważnym czynnikiem, który determinuje proliferację i różnicowanie komórek mięśniowych, jak również hamowanie ich apoptozy. Witamina D jest syntetyzowana w skórze. Niewiele jest jednak produktów spożywczych, które są dobrymi jej źródłami. Są to głównie: oleje rybne, ryby oraz produkty wzbogacane w witaminę D, takie jak produkty mleczne i margaryny. Osoby, które są szczególnie narażone na niedobór tej witaminy powinny stosować jej suplementację.
Źródło:
Roczniki Państwowego Zakładu Higieny; 2014, 65, 4
0035-7715
Pojawia się w:
Roczniki Państwowego Zakładu Higieny
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Gender differential in the incidence of diabetes mellitus among the patients in Udi Local Government Area of Enugu state, Nigeria
Autorzy:
Chukwu, B.N.
Ezebuiro, V.O.
Samuel, E.S.
Nwachukwu, K.C.
Powiązania:
https://bibliotekanauki.pl/articles/11829.pdf
Data publikacji:
2013
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
gender
incidence
diabetes mellitus
insulin
hyperglycemia
glucose
patient
human disease
metabolic disease
Udi Local Government Area
Enugu state
Nigeria
Opis:
Diabetes Mellitus is a chronic metabolic disease characterized by hyperglycemia and disturbances of carbohydrate, fat and protein metabolism. It is a major public health problem and disease burden worldwide, and especially in Nigeria. This study determined the gender differential in the incidence of Diabetes mellitus among the patients in Udi L.G.A of Enugu State. Three research questions and one hypothesis were formulated to guide the study. Descriptive survey design was employed. A sample of 343 diabetes mellitus patients were randomly selected and used for the study. Researchers design data documentary profoma was used to collect the data from selected health facilities in respect to the patients’ gender and their fasting sugar level as contained in their folder or hospital record/register. Frequency and percentages was used to answer research question while the null hypothesis was tested using Chi- square at 0.05 level of significance. The finding of the result revealed a high incidence of Diabetes Mellitus in 2012, females recorded a high incidence of DM from 2008-2012 and high percentage of fasting blood sugar level than male. The finding also revealed no difference in the fasting blood sugar based on gender. It is recommended among others that diagnostic investigation on human placental lactose is advocated to reduce or stop its opposition to insulin secretion during pregnancy.
Źródło:
International Letters of Natural Sciences; 2013, 04
2300-9675
Pojawia się w:
International Letters of Natural Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Association of chosen microsatellite markers on chromosomes 10, 11p and 14q with IDDM susceptibility in the population of midwestern Poland
Autorzy:
Jungerman, M
Fichna, P
Powiązania:
https://bibliotekanauki.pl/articles/2047273.pdf
Data publikacji:
1996
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
microsatellite marker
human disease
chromosome
statistical analysis
Polska
susceptibility
insulin-dependent diabetes mellitus
health control
polymerase chain reaction
Wielkopolska region
diabetic child
population
Opis:
In search for new markers of insulin-dependent diabetes (IDDM) susceptibility we studied the CATT tetranucleotide repeat in intron 1 of tyrosine hydroxylase (TH) gene on chromosome lip, the CA repeat at T-cell receptor a chain (TCRA) locus on chromosome 14q and two CA repeats at D10S211 and D10S213 loci in the chromosome 10 region containing glutamic acid decarboxylase (GAD2) gene. Alleles at these microsatellite loci were identified in a population of diabetic children and unrelated healthy controls originating from Wielkopolska, a midwestern region of Poland. We found significant association of certain alleles at TH, TCRA and D10S211 loci with diabetes in the population under study. On the contrary, none of the alleles at D10S213 locus was associated with the disease. Our findings indicate that typing of microsatellite markers may represent useful additional tool for identifying individuals at high risk of developing IDDM. Regarding loci on chromosome 10 our data and data published by other authors may suggest the extistence of two separate regions of association with IDDM susceptibility on this chromosome.
Źródło:
Journal of Applied Genetics; 1996, 37, 2; 217-228
1234-1983
Pojawia się w:
Journal of Applied Genetics
Dostawca treści:
Biblioteka Nauki
Artykuł
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