Temat: haemolysis - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: A New Method for Assessing Haemolysis in a Rotary Blood Pump Using Large Eddy Simulations (LES)
Autorzy:: Szwast, M.
Moskal, A.
Piątkiewicz, W.
Powiązania:: https://bibliotekanauki.pl/articles/185020.pdf
Data publikacji:: 2017
Wydawca:: Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:: rotary blood pump
large eddy simulations
haemolysis
obrotowa pompa krwi
duże symulacje wirów
hemoliza
Opis:: The opportunity to assess haemolysis in a designed artificial heart seems to be one of the most important stages in construction. We propose a new method for assessing haemolysis level in a rotary blood pump. This method is based on CFD calculations using large eddy simulations (LES). This paper presents an approach to haemolysis estimation and shows examples of numerical simulation. Our method does not determine the value of haemolysis but allows for comparison of haemolysis levels between different artificial heart constructions.
Źródło:: Chemical and Process Engineering; 2017, 38, 2; 231-239
0208-6425
2300-1925
Pojawia się w:: Chemical and Process Engineering
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 2.

Tytuł:: Haemocompatibility and cytotoxic studies of non-metallic composite materials modified with magnetic nano and microparticles
Autorzy:: Szymonowicz, M.
Rybak, Z.
Fraczek-Szczypta, A.
Paluch, D.
Rusak, A.
Nowicka, K.
Blazewicz, M.
Powiązania:: https://bibliotekanauki.pl/articles/306490.pdf
Data publikacji:: 2015
Wydawca:: Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
Tematy:: nanokompozyty
cząstki magnetyczne
hemoliza
żywotność komórkowa
koagulacja
nanocomposite
magnetic particles
polysulfone
haemolysis
cell viability
coagulation systems
Opis:: Purpose: Preventing the formation of blood clots on the surface of biomaterials and investigation of the reasons of their formation are the leading topics of the research and development of biomaterials for implants placed into the bloodstream. Biocompatibility and stability of a material in body fluids and direct effect on blood cell counts components are related both to the structure and physico-chemical state of an implant surface. The aim of this study was to determine haemocompatibility and cytotoxicity of polysulfone-based samples containing nano and micro particles of magnetite (Fe3O4). Methods: The polysulfone-based samples modified with nanometric and micrometric magnetite particles were examined. Physicochemical properties of the composites were determined by testing their wettability and surface roughness. The action of haemolytic, activation of coagulation system and cytotoxicity of composites was evaluated. Results: Wettability and roughness of materials were correlated with nanoparticles and microparticles content. In the tests of plasma coagulation system shortening of activated partial thromboplastin time for polysulfone with nano magnetite and with micro magnetite particles was observed in comparison with pure polysulfone. Prothrombine time and thrombine time values as well as fibrinogen concentration were unchanged. Haemolysis values were normal. Morphology and viability of cells were normal. Conclusions: Composites made from polysulfone modified with nanoparticles and microparticles of magnetite cause neither haemolytic nor cytotoxic reaction. These composites evoke plasma endogenous system activation.
Źródło:: Acta of Bioengineering and Biomechanics; 2015, 17, 3; 49-58
1509-409X
2450-6303
Pojawia się w:: Acta of Bioengineering and Biomechanics
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 3.

Tytuł:: The evaluation of resorbable haemostatic wound dressings in contact with blood in vitro
Autorzy:: Szymonowicz, M.
Kucharska, M.
Wiśniewska-Wrona, M.
Dobrzyński, M.
Kołodziejczyk, K.
Rybak, Z.
Powiązania:: https://bibliotekanauki.pl/articles/306978.pdf
Data publikacji:: 2017
Wydawca:: Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
Tematy:: opatrunek
chitozan
alginian
mikrofibrydy
nanofibrydy
hemoliza
haemostatic
dressing
chitosan-alginate
nanofibrids
microfibrids
haemolysis
plasmatic clotting system
Opis:: Purpose: For many years research has been conducted on the development of resorbable, polymer, haemostatic materials designed to provide first aid and preliminary protection of injuries. The biological properties in vitro of a dressing in powder form called Hemoguard are expected to provide the ability to instantaneously stem bleeding with safe conditions of use. The aim of the study was to evaluate the haemostatic properties of a model of dressing based on micro- and nanofibrids of the chitosan, sodium/calcium alginate and/or carboxymethylcellulose complex. Dressings were prepared by spray-drying and freeze-drying. Methods: Human whole blood was subjected to timed contact with the haemostatic dressing model. Haemolytic action was determined by assaying the degree of haemolysis and evaluating blood cell morphology. Haemostatic action was determined on the basis of selected parameters of plasmatic clotting systems. Results: Dressings prepared by freeze-drying activated the coagulation system. The haemolytic index, plasma haemoglobin concentration values and blood cell morphological shapes were normal. Dressings prepared by spray-drying significantly activated coagulation. Activation of the coagulation process was evidenced by shorter clotting time of the plasma coagulation system and a longer process of clot formation. The dressing was associated with an increased haemolytic index and higher plasma haemoglobin concentration. The morphological shape of blood cells changed. Conclusions: The model of multi-resorbable wound dressings has haemostatic properties. The materials activate the clotting process more quickly than a single-dressing model. Increased activity was found for dressings prepared by spray-drying.
Źródło:: Acta of Bioengineering and Biomechanics; 2017, 19, 1; 151-165
1509-409X
2450-6303
Pojawia się w:: Acta of Bioengineering and Biomechanics
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 4.

Tytuł:: Wpływ węgla pirolitycznego na parametry morfologiczne krwi
Effect of pyrolytic carbon on the morphological parameters of blood
Autorzy:: Szymonowicz, M.
Janus, A.
Pielka, S.
Obłąkowska, D.
Błażewicz, S.
Powiązania:: https://bibliotekanauki.pl/articles/286181.pdf
Data publikacji:: 2010
Wydawca:: Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Tematy:: węgiel pirolityczny
hemoliza
wskaźniki czerwonokrwinkowe
krwinki białe
płytki krwi
pyrolytic carbon
haemolysis
red cells parameters
white cells
platelets
Opis:: W pracy przedstawiono analizę ilościową wybranych parametrów morfologicznych krwi po jej czasowym kontakcie z materiałem węglowym LTI. Na podstawie uzyskanych wyników nie stwierdzono zmian w wartościach parametrów układu czerwonokrwinkowego, natomiast zaobserwowano zmiany w wartościach parametrów układu białokrwinkowego i płytkowego. Zaobserwowane zmiany w wartościach parametrów morfologicznych nie przekraczają zakresu wartości referencyjnych dla tych wskaźników.
A quantitative analysis of selected morphological parameters of blood after its temporal contact with LTI carbon material was presented in the study. The obtained results indicate that the values of parameters of erythrocyte system did not change, while the values of parameters of leukocyte and platelet systems were altered. The changes in the values of parameters did not exceed the range of referential values for these indexes.
Źródło:: Engineering of Biomaterials; 2010, 13, no. 96-98; 83-87
1429-7248
Pojawia się w:: Engineering of Biomaterials
Dostawca treści:: Biblioteka Nauki

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