- Tytuł:
- Cardiovascular complications during the treatment of castration-resistant prostate cancer with the use of modern antiandrogens: abiraterone acetate and enzalutamide
- Autorzy:
-
Grabysa, Radosław
Chmielewska, Agnieszka - Powiązania:
- https://bibliotekanauki.pl/articles/2047222.pdf
- Data publikacji:
- 2021-09-13
- Wydawca:
- Medical Education
- Tematy:
-
abiraterone acetate
enzalutamide
castration resistant prostate cancer
cardiovascular - Opis:
- Modern antiandrogens: abiraterone acetate (inhibitor of CYP17 cytochrome) and enzalutamide (irreversible inhibitor of androgen receptor) are the drugs that are increasingly often administered in treatment of castration-resistant prostate cancer. Despite their clinical efficacy, especially in terms of prolonged survival and improved quality of life of patients, they pose of problem for a practicing oncologist such as possible cardiovascular complications (particularly arterial hypertension), which may lead to the cessation of this form of therapy. This article provides a brief overview of the mechanisms responsible for the above complications, including practical recommendations in the event such complications arise. A simple scheme of action for control of cardiovascular risk factors has been presented, which can improve the prognosis in this population of patients.
- Źródło:
-
OncoReview; 2021, 11, 3; 61-67
2450-6125 - Pojawia się w:
- OncoReview
- Dostawca treści:
- Biblioteka Nauki
Artykuł