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Wyszukujesz frazę "dysbiosis" wg kryterium: Temat


Wyświetlanie 1-5 z 5
Tytuł:
The importance of intestinal dysbiosis in mood disorders
Autorzy:
Wójcik, Magdalena
Boreński, Grzegorz
Poleszak, Julita
Szabat, Marta
Złakowska, Paula
Milanowska, Joanna
Powiązania:
https://bibliotekanauki.pl/articles/1076059.pdf
Data publikacji:
2019
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
depression
dysbiosis
mood disorders
psychobiotics
Opis:
Intestinal bacteria and the microbiota-brain-intestin axis have been the subject of intense research in the last decade. Until recently, it seemed unlikely to combine fecal microflora with mood disorders. The growing amount of animal research shows that one of the etiological factors of mood disorders may be irregularities in this area. Evidence indicates the existence of an extremely important two-way relationship between bacteria, intestines and the brain, and that this interaction is complex and takes place on many levels. Understanding and analyzing this dependency gives new possibilities in the therapy of mood disorders, such as the use of psychobiotics, prebiotics or drugs which selectively eliminate specific bacterial strains (antimicrobials). Psychobiotics are „good” bacteria which, when consumed in appropriate doses, have a positive effect on the intestinal axis and on the condition of patients with mental disorders. Studies on their use show good results in the treatment of diseases such as depression. In people suffering from depression, significant differences in the composition of the intestinal microflora were observed, which speaks for its essential role in this disease. Even greater role of bacteria in mood disorders favors research that proves that fecal microbiota transplant entails consequences in the form of behavioral changes.
Źródło:
World Scientific News; 2019, 117; 147-157
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Correction by lisozyme of biochemical changes in periodontium of rats with Alloxane Diabetes
Autorzy:
Levitsky, A.P.
Stupak, E.P.
Powiązania:
https://bibliotekanauki.pl/articles/1032520.pdf
Data publikacji:
2014
Wydawca:
Uniwersytet Kazimierza Wielkiego w Bydgoszczy
Tematy:
alloxane diabetes
periodont
inflammation
dysbiosis
mineralization
lysozyme
Opis:
Aim. Aim of this study is to investigate gingivitis development in rats with experimentally induced diabetes mellitus type 1 and study of therapeutic and prophylactic actions lysozyme on periodontal condition. Methods. Alloxane diabetes has been induced by single injection of alloxane, in dose 100 mg/kg. A gel with lysozyme in concentration 2 mg/ml inflicted on the gum everyday. Taking out the animals from experiment performed at 21-th day. In gomogenates of gums the biochemical markers were estimated: malone dyaldegyde, elastase, urease, lysozyme, catalase. In homogenates of alveolar bone the activity of phosphatases, proteolytic activity was determined. Results. With alloxane diabetes in gum increased levels of biochemical markers of inflammation and increases the degree of disbiosis. In alveolar bone increases the activity of acid phosphatase and dropping the index mineralization. Appliques on a gum gel with lysozyme fixes the phenomenon of dysbiosis and inflammation in the gum, restores the index of mineralization in the alveolar bone. Conclusion. In the pathogenesis of periodontal disorders in diabetes mellitus plays an important role developing of dysbiosis. For prevent the development it periodontal complication need the use of lysozyme gel.
Źródło:
Journal of Health Sciences; 2014, 4, 1; 161-170
1429-9623
Pojawia się w:
Journal of Health Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Ability of Lactobacillus plantarum LS/07 to modify intestinal enzymes activity in chronic diseases prevention
Autorzy:
Hijová, Emília
Kuzma, Jozef
Strojný, Ladislav
Bomba, Alojz
Bertková, Izabela
Chmelárová, Anna
Hertelyová, Zdena
Benetinová, Veronika
Štofilová, Jana
Ambro, Ľuboš
Powiązania:
https://bibliotekanauki.pl/articles/1038694.pdf
Data publikacji:
2017
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
Sprague-Dawley rats
bacterial enzyme
cancer
atherosclerosis
dysbiosis
Opis:
The ability of probiotic strain Lactobacillus plantarum LS/07 to modify the activity of intestinal bacterial enzymes - β-glucuronidase (β-GLUCUR), β-galactosidase (β-GAL), and β-glucosidase (β-GLU) in prevention of chronic diseases - cancer, atherosclerosis and dysbiosis was investigated. The male Sprague-Dawley rats were randomly divided into 12 experimental groups: controls groups - C (control), AT (atherosclerotic), CC (carcinogenic), dysbiotic groups - each group in combination with antibiotics (ATB), probiotics groups - in combinatioan with probiotic (PRO) alone, and each group with combination of antibiotic and probiotic (ATB+PRO). In the control group the β-glucuronidase activity did not change throughout the experiment. High fat diet in atherosclerotic group significantly increased the activity of β-glucuronidase (P<0.001) and β-glucosidase (P<0.01). Azoxymethane application in carcinogenic group significantly increased β-glucuronidase (P<0.01), but reduced β-glucosidase (P<0.01) activity. Daily application of probiotics alone and in combination with antibiotic increased β-galactosidase, of β-glucosidase, and decreased β-glucuronidase activity. In control antibiotic group we observed significant increase in β-glucuronidase (P<0.05) and decreased β-glucosidase (P<0.01) activity which can be caused by the change of microflora in favor of coliform bacteria. These findings indicate the positive effects of probiotic Lactobacillus plantarum LS/07 and suggest its use in disease prevention in human medicine and some animal species.
Źródło:
Acta Biochimica Polonica; 2017, 64, 1; 113-116
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Развитие дисбиоза в пародонте крыс после спленэктомии
Development of dysbiosis in periodontal tissues in rats after splenectomy
Autorzy:
Tomilina, T.V.
Powiązania:
https://bibliotekanauki.pl/articles/1032517.pdf
Data publikacji:
2014
Wydawca:
Uniwersytet Kazimierza Wielkiego w Bydgoszczy
Tematy:
спленэктомия
десна
дисбиоз
сепсис
лизоцим
гиалуроновая кислота
splenectomy
gums
dysbiosis
sepsis
lysozyme
hyaluronic acid
Opis:
Спленэктомия у крыс вызывает развитие в десне дисбиоза, а в организме сепсиса, который проявляется значительным ростом активности уреазы, снижением активности лизоцима и содержания гиалуроновой кислоты
Spleen is central organ in the body's immune system. Removal of the spleen leads to immune deficiency that causes the development of intestinal dysbiosis. Aim - determine the state of dysbiosis in periodontum of rats after splenectomy. Methods. In Wistar rats were removed spleen and after 7 days were determined urease activity in gingiva (a marker of microbial contamination) and lysozyme (a measure of nonspecific immunity). By the ratio of relative activities urease and lysozyme calculated degree of dysbiosis. Furthermore, was determined in gingiva the level of inflammation markers (MDA, elastase) and hyaluronic acid content. Results. Removal of the spleen leads to sepsis development and death of nearly 50% of rats in 7 days. In gingiva significantly increased the urease activity (by 8 times) and decreases the activity of lysozyme (6 times), which leads to a manifold increase the degree of dysbiosis. Furthermore, in 2 times content of hyaluronic acid decreases in gingiva. Conclusion. Splenectomy causes the development of dysbiosis in periodontum, the basis of which may lie in reduction of hyaluronic acid.
Źródło:
Journal of Health Sciences; 2014, 4, 1; 125-134
1429-9623
Pojawia się w:
Journal of Health Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
FECAL MICROBIOTA TRANSPLANTATION IN ADULTS AS A MODERN FORM OF PAST “COPROTHERAPY”: HOPE OR HYPE?
Autorzy:
Ksiądzyna, Dorota
Powiązania:
https://bibliotekanauki.pl/articles/895703.pdf
Data publikacji:
2020-06-29
Wydawca:
Polskie Towarzystwo Farmaceutyczne
Tematy:
irritable bowel syndrome
dysbiosis
Clostridium difficile
fecal microbiota transplantation
intestinal microbiota
inflammatory bowel disorders
Opis:
The influence of intestinal microbiota on the human health and disease is of great importance. Fecal microbiota transplantation (FMT) defined as the transfer of the stool-derived microbiota of the distal gastrointestinal (GI) tract from a healthy donor to a patient with a disease attributable to intestinal dysbiosis is, in addition to the use of probiotics, prebiotics, synbiotics and eubiotics, one of the methods to restore eubiosis. Thorough medical history and physical examination followed by a set of blood and stool laboratory tests should be performed in a potential stool donor. Stool-derived microbiota may be administered through the upper and/or lower GI tract. FMT is believed to be a well-tolerated and, in general, safe procedure. The emergence of stool banks of frozen feces-derived material containing intestinal microbiota and the availability of convenient oral capsules with selected components of feces would definitely facilitate the use of this method in both research and the clinics. An inflammation caused by Clostridium difficile is the most often indication for FMT. Other conditions include inflammatory bowel disease, irritable bowel syndrome or the eradication of multi-drug resistant microorganisms. However, the list of potential indications rapidly increases. Further randomized double-blind studies in humans are needed to confirm a real benefit-risk ratio and clinical value of FMT, especially in extraintestinal disorders like obesity, diabetes mellitus, metabolic syndrome, fatty liver disease, hepatic encephalopathy, allergy, autism, depression or dementia.
Źródło:
Acta Poloniae Pharmaceutica - Drug Research; 2020, 77, 3; 391-401
0001-6837
2353-5288
Pojawia się w:
Acta Poloniae Pharmaceutica - Drug Research
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-5 z 5

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