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    Wyświetlanie 1-7 z 7
    Tytuł:
    Geographic variability of major non-traumatic lower limb amputations in diabetic and non-diabetic patients in Poland
    Autorzy:
    Wierzba, W.
    Krasnodębski, P.
    Śliwczyński, A.
    Karnafel, W.
    Powiązania:
    https://bibliotekanauki.pl/articles/2085410.pdf
    Data publikacji:
    2020
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    diabetes mellitus
    diabetic patients
    non-diabetic patients
    non-traumatic lower limb amputations
    Opis:
    Introduction. High amputation of the lower limb not only causes immense physical disability but also the destruction of the patient’s mental state, and helps to shorten life of patients with diabetes. The incidence of amputations in diabetic patients is 10 times higher in comparison to non-diabetic subjects (2.8% vs. 0.29%). The purpose of the study is an analysis of the geographic variability of major non-traumatic lower limb amputation in diabetic and non-diabetic patients in Poland. Materials and method. All major non-traumatic lower limb amputations performed for the first time, in particular data between 1 January 2013 – 31 December 2013, and between 1 January 2014 – December 2014, were identified in the National Health Fund (NHF) database. In the presented study, the patients were grouped in relevant provincial departments of the NHF according to their place of residence, and not according to the hospital where lower limb amputation was performed. Results. In 2013 in Poland, 4,727 major non-traumatic lower limb amputation were performed in diabetic patients, and 4,350 in 2014. On the other hand, in non-diabetic patients, 3,469 major non-traumatic lower limb amputations were performed in 2013, and 3149 in 2014. The mean number indicator of major non-traumatic lower limb amputations in diabetic patients in Poland, compared to the average indicator of amputations in patients without diagnosed diabetes in Poland was 19.9-fold in 2013 and 19.4-fold higher in 2014. Conclusions. In populations of diabetic patients and individuals without diagnosed diabetes major non-traumatic lower limb amputations are performed over 19-fold more frequently.
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2020, 27, 1; 76-79
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Diabetic autonomic neuropathy of the gastrointestinal tract - etiopathogenesis, diagnosis, treatment and complications
    Autorzy:
    Kuzemko, Dorota
    Rymarz, Ewa
    Prystupa, Andrzej
    Dzida, Grzegorz
    Mosiewicz, Jerzy
    Powiązania:
    https://bibliotekanauki.pl/articles/972715.pdf
    Data publikacji:
    2017
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    diabetic neuropathies
    diabetes complications
    diabetes mellitus
    gastrointestinal autonomic neuropathy
    Opis:
    Introduction. Late complications of diabetes mellitus are a serious challenge for physicians treating diabetic patients. Micro- and macro-angiopathic changes are of the most severe sequels. However, it should be remembered that the effects of long-term diabetes are also associated with changes in the peripheral nervous system. One of the complications most troublesome for patients is diabetic autonomic neuropathy of the gastrointestinal (GI) tract. Objective. The review article presents the pathogenesis of diabetic neuropathy of the autonomous gastrointestinal tract, and advances in the diagnosis and treatment of this disease. The study used materials in the database which demonstrate current standards of conduct, based on the principles of EBM. Brief description of the state of knowledge. Diabetic neuropathy is one of the most common complications of diabetes mellitus. According to epidemiologists, it affects 10% to even 100% of patients with long-standing disease. Damage to the nervous fibres mainly results from hyperglycaemia, which leads to the typical symptoms of dysfunction of GI tract segments. The main additional examinations include abdominal ultrasound (US) and abdominal X-ray. In cases with oesophageal disorders accompanied by dysphagia, gastroscopy is found useful for excluding possible neoplastic lesions. The gold standard for evaluation of gastric emptying is radioisotopic scintigraphy, however it is available only in some specialistic departments. Other recommended methods include: manometry, EGG, insulin tests, NMR and expiratory tests. To date, the problem has been managed symptomatically; in special cases, surgical interventions have been required. Conclusions. At present, a wide array of treatment options is available, including new forms of drugs and less radical surgical procedures carried out in numerous centres worldwide.
    Źródło:
    Journal of Pre-Clinical and Clinical Research; 2017, 11, 1; 6-9
    1898-2395
    Pojawia się w:
    Journal of Pre-Clinical and Clinical Research
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The effect of diabetes on the connective tissue and the bone-joint system
    Autorzy:
    Chwalba, Artur
    Otto-Buczkowska, Ewa
    Powiązania:
    https://bibliotekanauki.pl/articles/454871.pdf
    Data publikacji:
    2018
    Wydawca:
    Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
    Tematy:
    diabetes mellitus
    diabetic osteopathy
    limited joint mobility
    joint disorders
    Opis:
    Introduction. Diabetes is associated with a number of complications, including renal disease, peripheral neuropathy, retinopathy, and vascular events. Aim. Article presents the research results reported in the scientific literature about the influence of diabetes on connective tissue and the bone-joint system. Material and methods. Analysis of literature. Conclusion. Due to its multi-systemic nature, the development of additional manifestations, such as musculoskeletal complications, is possible including, for example diabetic osteopathy, limited joint mobility, joint disorders, and other, many of which are subclinical and correlated with the disease duration and its inadequate control. They should be recognized and treated properly, because their management improves the patients’ quality of life.
    Źródło:
    European Journal of Clinical and Experimental Medicine; 2018, 3; 233-238
    2544-2406
    2544-1361
    Pojawia się w:
    European Journal of Clinical and Experimental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Prevention of diabetes in primary healthcare based on the health policy program for early detection and prevention of diabetes and its complications in working individuals in the Lubusz province
    Autorzy:
    Bonikowska, Iwona
    Jasik-Pyzdrowska, Justyna
    Towpik, Iwona
    Powiązania:
    https://bibliotekanauki.pl/articles/552077.pdf
    Data publikacji:
    2018
    Wydawca:
    Stowarzyszenie Przyjaciół Medycyny Rodzinnej i Lekarzy Rodzinnych
    Tematy:
    primary health care
    diabetes mellitus
    pre-diabetic state
    primary prevention.
    Źródło:
    Family Medicine & Primary Care Review; 2018, 4; 313-319
    1734-3402
    Pojawia się w:
    Family Medicine & Primary Care Review
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The association between ALR2 -106C > T gene polymorphisms and diabetic retinopathy susceptibility in diabetes mellitus patient: a systematic review and meta-analysis
    Autorzy:
    Putri, Indah Sagitaisna
    Rezkita, Bastomy Eka
    Irving, Steven
    Azmiardi, Akhmad
    Powiązania:
    https://bibliotekanauki.pl/articles/4175390.pdf
    Data publikacji:
    2023-03-27
    Wydawca:
    Medical Education
    Tematy:
    ALR2 gene
    diabetic retinopathy
    diabetes mellitus
    gene polymorphism
    polyol pathway
    Opis:
    Aldose reductase gene polymorphisms has been indicated to be associated with diabetic retinopathy (DR). The research data were from PubMed and EMBASE. We identified -106C > T single nucleotide polymorphism (SNP). Pool odds ratio (OR) with 95% CI were calculated. Nine studies were included. ALR2 106C > T gene polymorphisms was associated with the increased risk of DR in T1DM (C vs. T, OR = 2.07, p = 0.001; CC vs. CT + TT, OR = 2.56, p = 0.005). T allele and TT genotype were associated with decreased risk of DR in T1DM (OR = 0.48, p = 0.0001 and OR = 0.12, p = 0.0005). In conclusion, C allele and CC genotype may be a risk factor, while T allele and TT genotype may serve as protective factor for DR in T1DM patient.
    Źródło:
    OphthaTherapy; 2023, 10, 1; 12-21
    2353-7175
    2543-9987
    Pojawia się w:
    OphthaTherapy
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Long-term complications of diabetes and the risk of diabetic foot
    Przewlekłe powikłania cukrzycy i ryzyko stopy cukrzycowej
    Autorzy:
    Krysiak-Zielonka, I.
    Powiązania:
    https://bibliotekanauki.pl/articles/2052827.pdf
    Data publikacji:
    2018
    Wydawca:
    Akademia Bialska Nauk Stosowanych im. Jana Pawła II w Białej Podlaskiej
    Tematy:
    diabetes mellitus
    chronic complications of diabetes
    diabetic foot
    cukrzyca
    przewlekłe powikłania cukrzycy
    stopa cukrzycowa
    Opis:
    Background. Chronic complications of diabetes are presently the most vital problem in diabetology and the most significant challenge in the treatment of the diseases. Because of peripheral neuropathy and macroangiopathy, people with diabetes are particularly vulnerable to foot problems. The following study aims to evaluate the development of chronic complications in patients with type 2 diabetes, with a particular focus on the prevalence of limb ischemia symptoms. Material and methods. The study involved patients with type 2 diabetes mellitus and nondiabetic persons at a similar age. Diabetics were divided into 2 groups. Group 1 consisted of type 2 diabetic patients with no trophic lesions of the limbs; Group 2 included patients with diabetic foot disease; and the control group (Group 3) were the non-diabetic elderly. The study was to analyse the incidence of retinopathy, nephropathy and neuropathy in both diabetic groups. Besides, it was to evaluate changes in macroangiopathy among diabetic patients and the control group. Results. In all groups, symptoms of lower limb ischaemia were assessed, which allowed making comparisons between them. The studied material indicated that the occurrence of diabetic ulcers is mostly associated with macroangiopathy and its symptoms, polyneuropathy and particular types of neuropathy, retinopathy and horny foot skin. Conclusions. An interdisciplinary approach to the problem of the diabetic foot allows recognising its early clinical symptoms.
    Wprowadzenie. Przewlekłe powikłania cukrzycy są obecnie najważniejszym problemem w diabetologii i stanowią największe wyzwanie w leczeniu cukrzycy. Z powodu obwodowej neuropatii i makroangiopatii chorzy na cukrzycę są grupą szczególnie narażoną na problemy zdrowotne stóp. Celem pracy jest ocena rozwoju przewlekłych powikłań u chorych na cukrzycę typu 2 ze szczególnym uwzględnieniem analizy częstości występowania objawów niedokrwienia kończyn. Materiał i metody. Badaniami objęto chorych z cukrzycą typu 2 oraz osoby niechorujące na cukrzycę w podobnym przedziale wiekowym. Diabetyków podzielono na 2 grupy. Grupę 1- stanowili chorzy na cukrzycę typu 2 bez zmian troficznych kończyn, grupę 2- stanowili chorzy z zespołem stopy cukrzycowej, grupę kontrolną (grupa 3)- stanowiły osoby w wieku podeszłym niechorujące na cukrzycę. Przeanalizowano występowanie retinopatii, nefropatii i neuropatii w obu grupach diabetyków. Oceny zmian o charakterze makroangiopatii dokonano wśród chorych na cukrzycę i w grupie kontrolnej. Wyniki. We wszystkich grupach oceniano objawy niedokrwienia kończyn dolnych. Dokonano porównań między grupami. W badanym materiale występowanie owrzodzeń cukrzycowych wiąże się w największym stopniu z makroangiopatią i jej objawami, polineuropatią i poszczególnymi typami neuropatii, retinopatią oraz występowaniem zrogowaciałego naskórka stóp. Wnioski. Interdyscyplinarne podejście do problemu stopy cukrzycowej umożliwia rozpoznawanie jej wczesnych objawów klinicznych.
    Źródło:
    Health Problems of Civilization; 2018, 12, 1; 14-21
    2353-6942
    2354-0265
    Pojawia się w:
    Health Problems of Civilization
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Are we helping or harming our insulin-treated diabetic patients during ambulatory treatment?
    Autorzy:
    Szczesniak, G.
    Dziemidok, P.
    Paprzycki, P.
    Powiązania:
    https://bibliotekanauki.pl/articles/50293.pdf
    Data publikacji:
    2013
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    helping
    harming
    insulin-treated patient
    diabetic patient
    ambulatory treatment
    diabetes mellitus
    insulin therapy
    body weight
    hemoglobin
    knowledge
    behaviour
    Opis:
    Introduction. Correctness of insulin treatment depends on both the experience and skills of the doctor and knowledge and behaviour of the patient. Objective. Evaluation the adequacy of insulin doses administered to diabetes patients in ambulatory conditions. Material and methods. The treatment of 59 patients hospitalized in the Diabetology Ward was evaluated at admission, discharge and 3 months after hospitalization. Results. The mean daily doses of insulin significantly differed at times of evaluation and were: 53.90, 39.31 and 43.34 units, respectively (p≈0.000001). A significant reduction of body weight, 90.86 vs. 88.25 kg (p≈0.000001), was obtained only during hospitalization, and was maintained 3 months after discharge (87.86 kg). Significant differences were also noted in the body mass index (33.44 vs. 32.48 vs. 32.37 kg/m2, p≈0.000001). The change in waist circumference was not statistically significant (107.87 vs. 104.89 cm; p≈0.06). A decrease in the number of hypoglycaemia episodes was observed, but were statistically insignificant (25 vs. 23; p≈0.7). Three months after hospitalization an insignificant decrease of HbA1c level was noted (8.41% vs. 8.03%; p≈0.07). Conclusions. During treatment in the Diabetology Ward the procedure of choice was more frequently a reduction than an increase in insulin doses. This management led to the reduction of the patients’ body weight, improvement of glycaemia, without any significant effect on the diabetes control determined by the HbA1c level.
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2013, 20, 2
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-7 z 7

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