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Wyszukujesz frazę "Czarnecka, B." wg kryterium: Autor


Wyświetlanie 1-2 z 2
Tytuł:
The effect of titanium alloy modified with a-C:N:H and a-SiCxNY(H) coatings on adhesion and immune response of human osteoblast-like MG-63 cells
Autorzy:
Ścisłowska-Czarnecka, A.
Menaszek, E.
Kołaczkowska, E.
Januś, M.
Stypuła, B.
Powiązania:
https://bibliotekanauki.pl/articles/284995.pdf
Data publikacji:
2008
Wydawca:
Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Tematy:
titanium alloy
a-C:N:H and a-SiCxNy(H) coatings
osteoblast-like MG-63 cells
cell adhesion
cytokines
Opis:
The study was conducted in order to determine the effects of modified titanium alloy (Ti-6Al-4V) surfaces on the biological response of a human osteoblast-like cell line. MG-63 cells were cultured on disk-shaped Ti-alloys: unmodified, and covered with a-C:N:H or a-SiCxNy(H) layers. Interactions between materials and cells were examined through determination of cells adhesion and secretion of cytokines involved in the development of immune response.
Źródło:
Engineering of Biomaterials; 2008, 11, no. 81-84; 126-128
1429-7248
Pojawia się w:
Engineering of Biomaterials
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Porous titanium scaffolds with modified surface: in vitro cell biology assessment
Autorzy:
Ścisłowska-Czarnecka, A.
Menaszek, E.
Szaraniec, B.
Chłopek, J.
Kołaczkowska, E.
Powiązania:
https://bibliotekanauki.pl/articles/285246.pdf
Data publikacji:
2009
Wydawca:
Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Tematy:
osteoblasts
cytokines
cell adherence
morphology
titanium
hydroxyapatite
bioglass
CaO-SiO2
Opis:
Interaction of host cells with a biomaterial surface is important for biocompatibility and thus is essential for biomedical applications. Therefore investigations are undertaken to scrutinize for an appropriate surface coating with physical and chemical properties minimizing undesirable activation of immunological response. For this the current study was aimed at examining the effects of different surface modifications of titanium by its coating with ceramic materials - hydroxyapatite, bioglass and CaO-SiO2on osteoblast morphology and secretory activity. Titanium is known for its excellent mechanical properties but its surface has low bioactivity. We report that CaO-SiO2coating decreased a number of attached osteoblasts and altered their morphology. Moreover, the ceramic coatings temporarily upregulated release of pro-inflammatory cytokines IL-6 (all of them) and TNF-α (CaO-SiO2). However, overall the levels of the cytokines were low. In contrast, levels of neutrophil-attracting chemokine IL-8 were the highest. IL-8 was produced mostly by cells incubated with hydroxyapatite titanium coating in contrary to those incubated with either bioglass or CaO-SiO2titanium modifications. In conclusion, the titanium coated with ceramics such as hydroxyapatite or bioglass had the best effect on cell adhesion; however, hydroxyapatite might potentially stimulate destructive neutrophils while CaO-SiO2-coating has a negative effect on cell adhesion.
Źródło:
Engineering of Biomaterials; 2009, 12, 88; 5-10
1429-7248
Pojawia się w:
Engineering of Biomaterials
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-2 z 2

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