- Tytuł:
- Data mining methods for gene selection on the basis of gene expression arrays
- Autorzy:
-
Muszyński, M.
Osowski, S. - Powiązania:
- https://bibliotekanauki.pl/articles/329803.pdf
- Data publikacji:
- 2014
- Wydawca:
- Uniwersytet Zielonogórski. Oficyna Wydawnicza
- Tematy:
-
gene expression array
gene ranking
feature selection
clusterization measures
fusion
SVM classification
ekspresja genów
selekcja cech
klasyfikacja SVM - Opis:
- The paper presents data mining methods applied to gene selection for recognition of a particular type of prostate cancer on the basis of gene expression arrays. Several chosen methods of gene selection, including the Fisher method, correlation of gene with a class, application of the support vector machine and statistical hypotheses, are compared on the basis of clustering measures. The results of applying these individual selection methods are combined together to identify the most often selected genes forming the required pattern, best associated with the cancerous cases. This resulting pattern of selected gene lists is treated as the input data to the classifier, performing the task of the final recognition of the patterns. The numerical results of the recognition of prostate cancer from normal (reference) cases using the selected genes and the support vector machine confirm the good performance of the proposed gene selection approach.
- Źródło:
-
International Journal of Applied Mathematics and Computer Science; 2014, 24, 3; 657-668
1641-876X
2083-8492 - Pojawia się w:
- International Journal of Applied Mathematics and Computer Science
- Dostawca treści:
- Biblioteka Nauki
Artykuł