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Wyszukujesz frazę "Hyaluronic Acid" wg kryterium: Temat


Wyświetlanie 1-9 z 9
Tytuł:
Artificial skin composites
Autorzy:
Ładniak, Agata
Powiązania:
https://bibliotekanauki.pl/articles/2079951.pdf
Data publikacji:
2018
Wydawca:
Uniwersytet Marii Curie-Skłodowskiej. Wydawnictwo Uniwersytetu Marii Curie-Skłodowskiej
Tematy:
titanium dioxide,
chitosan
hyaluronic acid
skin substitutes
Opis:
Skin injuries are a health problem and can lead to serious, significant deterioration in the quality of life and, consequently, even illness and disability. Therefore, after wounding, immediate regeneration of the tissue is necessary to avoid further complications and pathogenesis. Consequently, many wound healing strategies have been developed, leading to the progress in constructing of multifunctional tissue substitutes for the skin, biomembranes, scaffolds and intelligent dressings. The field of science focusing on the creation of the above-mentioned products is tissue engineering (TE). Its main goal is to find a system that is able to replace or be a model that perfectly mimics the form and function of the skin. Research carried out on such constructs is mainly based on the analysis of mechanical properties (porosity, elasticity), as well as the assessment of the impact of individual components on processes related to the formation of new tissue as cell proliferation and differentiation, proliferation, angiogenesis - through in vivo studies (using animal models: mice, New Zealand rabbits) and in vitro (most often using mouse fibroblasts - L929). Skin constructions may have potential applications as wound dressings or skin substitutes in cases of severe skin damage.
Źródło:
Annales Universitatis Mariae Curie-Skłodowska, sectio AA – Chemia; 2018, 73, 1; 51-60
2083-358X
Pojawia się w:
Annales Universitatis Mariae Curie-Skłodowska, sectio AA – Chemia
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Characterisation of chitosan/hyaluronic acid blend films modified by collagen
Autorzy:
Lewandowska, Katarzyna
Sionkowska, Alina
Grabska, Sylwia
Michalska, Marta
Powiązania:
https://bibliotekanauki.pl/articles/1034575.pdf
Data publikacji:
2017
Wydawca:
Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
Tematy:
chitosan
collagen
hyaluronic acid
polymer blends
surface properties
Opis:
In the present study, thin films based on the blends of chitosan (Ch) and hyaluronic acid (HA) with and without collagen (Coll) were characterised using tensile tests, attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR) and thermogravimetric analysis (TGA). Ch/HA and Ch/HA/Coll polymer blends were prepared using the solvent evaporation technique. The interactions between polymer components in the binary and ternary blends were studied by FTIR analysis. Mechanical properties were studied and compared with those of simple polymer films. These results show that the addition of collagen into Ch/HA blends led to the increase of tensile strength and Young modulus. Moreover, it was found that the thermal stability of the Ch/HA binary blend significantly increased upon the addition of collagen.
Źródło:
Progress on Chemistry and Application of Chitin and its Derivatives; 2017, 22; 125-134
1896-5644
Pojawia się w:
Progress on Chemistry and Application of Chitin and its Derivatives
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The influence of the type solvent on the structure of chitosan blends with hyaluronic acid
Autorzy:
Lewandowska, Katarzyna
Sionkowska, Alina
Grabska, Sylwia
Powiązania:
https://bibliotekanauki.pl/articles/1034698.pdf
Data publikacji:
2016
Wydawca:
Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
Tematy:
chitosan
hyaluronic acid
microscopy.
polymer blends
surface properties
Opis:
The influence of the type solvent on the structure of chitosan, hyaluronic acid and their blend films was investigated. Aqueous acetic acid, hydrochloric acid, sodium chloride and aqueous acetic acid/NaCl were used as solvents for chitosan, hyaluronic acid and Ch/HA solution blends. Ch, HA and their blend films were prepared by casting technique. The homogeneity and morphology of chitosan blends were ascertained from the tapping-mode atomic force microscopy (AFM) and scanning electron microscopy (SEM). The changes of topography images are considered by determining the root mean square (RMS, Rq) deviation in the image data. The surface roughness of chitosan, hyaluronic acid and Ch/HA blended films was altered by mixing. The structure of chitosan blends with hyaluronic acid depends on the blend composition and on the solvent used for preparing the blend.
Źródło:
Progress on Chemistry and Application of Chitin and its Derivatives; 2016, 21; 147-153
1896-5644
Pojawia się w:
Progress on Chemistry and Application of Chitin and its Derivatives
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Effect of chitosan, hyaluronic acid and/or titanium dioxide on the physicochemical characteristic of phospholipid film/glass surface
Autorzy:
Ładniak, Agata
Jurak, Małgorzata
Wiącek, Agnieszka Ewa
Powiązania:
https://bibliotekanauki.pl/articles/109601.pdf
Data publikacji:
2019
Wydawca:
Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
Tematy:
chitosan
titanium dioxide
hyaluronic acid
phospholipid
adhesion
topography
Opis:
The production of preparations, whose destination action takes place in close proximity to living cells, increases the necessity to carry out studies concerning the determination of the biomaterial surface effect on the cellular response. In achieving this goal, physicochemical characteristic of the surface can be helpful. This can be established based on topography, chemical composition, wettability, and surface energy analysis. In addition, determining the changes of these properties which can occur as a result of surface modification will allow prediction of cell behaviour when contacting with biomaterial. In the study, the Langmuir-Blodgett technique was used. It enabled the transfer of the Langmuir monolayer formed from 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) to a solid support. The DPPC film imitated a natural biological membrane capable of interacting with the components of the liquid subphase: chitosan (Ch), hyaluronic acid (HA) and/or titanium dioxide (TiO2). Depending on the type and strength of interactions of phospholipid molecules with the components of the subphase, the films obtained on the solid support were characterized by specific surface properties. Their characteristics based mainly on values of the work of adhesion in connection with films topography, allowed for statement that it is possible to form semi-interpenetrating Ch network in which HA is entrapped, contributing to the enhanced adhesion of the DPPC film, additionally intensified by TiO2 inclusion. This type of research permit for better understanding of the interactions at the interface, cell membrane-Ch/HA/TiO2 and can be important in the creation of a new generation of skin or tissue substitutes.
Źródło:
Physicochemical Problems of Mineral Processing; 2019, 55, 6; 1535-1548
1643-1049
2084-4735
Pojawia się w:
Physicochemical Problems of Mineral Processing
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Biodegradable nonwoven activated polyester with chitosan: potential application in the cosmetic industry
Autorzy:
Gzyra-Jagieła, Karolina
Owczarek, Monika
Szkopiecka, Monika
Jagodzińska, Sylwia
Dymel, Marzena
Kudra-Miros, Patrycja
Kudra, Michał
Powiązania:
https://bibliotekanauki.pl/articles/1034126.pdf
Data publikacji:
2020
Wydawca:
Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
Tematy:
Neroli hydrolate
chitosan
collagen
cosmetic mask
hyaluronic acid
polyester nonwoven
Opis:
Textile products enriched with natural substances, e.g. hyaluronic acid, plant hydrolates, collagen and chitosan, may find wide application in cosmetics because of increasing consumer interest in natural products. Furthermore, in view of global environmental pollution, products that are produced through biochemical changes as a result of composting are sought. This makes it possible to enter such designed cosmetic products into the scheme of the currently desired circular economy. Compostable textiles are an ecological alternative to product backlogs and polluting the environment in the form of post-consumer waste. Therefore, this research work developed a technology for applying natural substances on a biodegradable polyester fibrous substrate. This study developed the optimal composition of a mixture consisting of natural substances with properties applicable to the cosmetic industry, for applications such as cosmetic masks to improve the appearance of the skin. The composition of active substances that have beneficial effects on the skin, e.g. moisturizing, regenerating, antibacterial and caring, was determined. The mixture was effectively applied on a spunbound nonwoven substrate of made from aliphatic-aromatic copolyester by impregnation. The employed polymer degraded in a compost environment and its modifiers additionally supported this process. The unique composition of the applied coating layer consisted of a mixture of sodium hyaluronate, collagen, bitter orange blossom hydrolate (Neroli) and chitosan lactate. The coated nonwoven fabric was subjected to physical, mechanical, microbiological as well as chemical purity and structural tests (Fourier transform infrared spectroscopy and scanning electron microscopy) and degree of degradation in a compost environment was assessed on the basis of its weight loss.
Źródło:
Progress on Chemistry and Application of Chitin and its Derivatives; 2020, 25; 94-110
1896-5644
Pojawia się w:
Progress on Chemistry and Application of Chitin and its Derivatives
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Surface characteristics of dppc monolayers deposited from titanium dioxide–chitosan–hyaluronic acid subphases on a glass support
Autorzy:
Ładniak, Agata
Jurak, Małgorzata
Wiącek, Agnieszka Ewa
Powiązania:
https://bibliotekanauki.pl/articles/1034201.pdf
Data publikacji:
2019
Wydawca:
Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
Tematy:
DPPC
chitosan
hyaluronic acid
surface free energy
titanium dioxide
topography
Opis:
The Langmuir-Blodgett technique was used to transfer the monolayers of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) from the subphase containing chitosan (Ch) and/or titanium(IV) oxide (TiO2) and/or hyaluronic acid (HA) on glass plates after a low-temperature air plasma treatment. The surface free energy and its components were determined on the basis of advancing and receding contact angle measurements of water (W), formamide (F), and diiodomethane (DM). To estimate the total surface free energy (), the contact angle hysteresis (CAH) model was used, and the obtained data were compared with the results calculated from the Lifshitz-van der Waals/acid–base (LWAB) approach. It was found that the subphase components modify the surface of the phospholipid monolayer by changing the type and magnitude of interactions. They were reflected as significant differences in the obtained values of total surface free energy and its components. These findings can help in the development of composite materials, thereby expanding the spectrum of applications for chitosan, TiO2, and HA, as well as understanding the interactions between biomaterial and cell.
Źródło:
Progress on Chemistry and Application of Chitin and its Derivatives; 2019, 24; 106 - 118
1896-5644
Pojawia się w:
Progress on Chemistry and Application of Chitin and its Derivatives
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Influence of the intermolecular interaction on physico-chemical properties of chitosan/hyaluronic acid blends
Autorzy:
Lewandowska, Katarzyna
Sionkowska, Alina
Grabska, Sylwia
Powiązania:
https://bibliotekanauki.pl/articles/1034820.pdf
Data publikacji:
2015
Wydawca:
Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
Tematy:
AFM microscopy
chitosan
hyaluronic acid
polymer blends
viscosity interaction parameters
Opis:
In the present study, the results of viscosity measurements in dilute solutions of chitosan (Ch) with hyaluronic acid (HA) are presented. Chitosan is blended with hyaluronic acid in aqueous 0.1M CH3COOH/0.2M NaCl and 0.3M NaCl respectively, or with the addition of HEPES. Viscosity measurements of dilute polymer solution were carried out in an Ubbelohde capillary viscometer. The intrinsic viscosity, [], and the viscosity interaction parameters, bm, have been determined for the binary (solvent/polymer) and ternary (solvent/polymer A/polymer B) systems. The homogeneity and morphology of chitosan blends were ascertained from the tapping-mode atomic force microscopy. The surface roughness of chitosan, hyaluronic acid and Ch/HA blended films was altered by mixing. The obtained results suggested that there was existence of the strong interactions between chitosan and hyaluronic acid.
Źródło:
Progress on Chemistry and Application of Chitin and its Derivatives; 2015, 20; 170-176
1896-5644
Pojawia się w:
Progress on Chemistry and Application of Chitin and its Derivatives
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Otrzymywanie oraz charakterystyka skafoldów sieciowanych kwasem taninowym na bazie chitozanu, kolagenu oraz kwasu hialuronowego
Preparation and characterization of tannic acid cross-linked scaffolds made of chitosan, collagen and hyaluronic acid
Autorzy:
Kaczmarek, B.
Sionkowska, A.
Markiewicz, E.
Kołodziejczak, A.
Powiązania:
https://bibliotekanauki.pl/articles/285464.pdf
Data publikacji:
2016
Wydawca:
Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Tematy:
kolagen
chitozan
kwas hialuronowy
sieciowanie
kwas taninowy
collagen
chitosan
hyaluronic acid
cross-linking
tannic acid
Opis:
Biopolimery są szeroko stosowane w dziedzinie biomateriałów. Są biokompatybilne, biodegradowalne oraz nietoksyczne dla ludzkiego organizmu. Celem niniejszych badań eksperymentalnych było otrzymanie kompozytów na bazie kolagenu, chitozanu oraz kwasu hialuronowego modyfikowanych poprzez dodatek kwasu taninowego. Biopolimery zostały wymieszane poprzez sporządzenie 1% roztworów każdego z nich, przy czym kolagen oraz chitosan były wymieszane w stosunku wagowym 50/50 oraz do tej mieszaniny zastosowano 1, 2 i 5 (w/w%) dodatek kwasu hialuronowego. Do mieszaniny dodano następnie 2, 5, 10 oraz 20 (w/w%) kwasu taninowego oraz otrzymano skafoldy metodą suszenia sublimacyjnego. Próbki zarówno z dodatkiem kwasu taninowego jak i bez niego zostały scharakteryzowane poprzez pomiar ich właściwości mechanicznych, analizę spektroskopii w podczerwieni (IR-ATR) oraz obrazowanie przy użyciu skaningowego mikroskopu elektronowego (SEM). Ponadto wyznaczono porowatość oraz gęstość każdego ze skafoldów. Wszystkie otrzymane próbki były porowate i nie zaobserwowano znaczących różnic w strukturze na zdjęciach SEM. Na widmach IR-ATR charakterystyczne piki polimerów takie jak: amidowe I, II, III oraz A były przesunięte po dodatku taniny w wyniku pojawienia się wiązań wodorowych oraz oddziaływań elektrostatycznych. Wyniki pokazują, że kwas taninowy może być wykorzystany jako czynnik sieciujący stosowany w celu modyfikacji właściwości biomateriałów.
Biopolymers are widely used in biomaterials science. They are biocompatible, biodegradable and non-toxic for human body. The aim of the study was to obtain scaffolds made of chitosan, collagen and hyaluronic acid modified by addition of tannic acid. The biopolymers were mixed as 1% solution, where collagen and chitosan were mixed in 50/50 (w/w%) and 1, 2 and 5 (w/w%) of hyaluronic acid was added. 2, 5, 10 and 20 (w/w%) of tannic acid was added to the mixture and scaffolds were obtained by freeze drying method. Samples with the tannic acid as well as without it were characterized by the mechanical parameters measurement, infrared spectroscopy (IR-ATR) and scanning electron microscopy (SEM). Moreover the porosity and density of the scaffolds were determined. The addition of tannic acid improves the mechanical properties and porosity of the scaffolds. All the scaffolds were porous and no significant changes in the structure were observed at the SEM images. In the IR-ATR spectra characteristic peaks of polymers as amide I, II, III and A were shifted after addition of tannic acid due to the presence of new hydrogen bonds and electrostatic interactions. The results show that tannic acid can be used as a cross-linking agent to modify the properties of the scaffolds.
Źródło:
Engineering of Biomaterials; 2016, 19, 136; 21-27
1429-7248
Pojawia się w:
Engineering of Biomaterials
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Chitozan jako składnik preparatów wspomagających leczenie urazów skóry
Chitosan preparations as a wound dressing material
Autorzy:
Zielińska, Agnieszka
Powiązania:
https://bibliotekanauki.pl/articles/2041453.pdf
Data publikacji:
2022-04-20
Wydawca:
Wydawnictwo Naukowe Medyk sp. z o.o.
Tematy:
chitozan
srebro koloidowe
kwas hialuronowy
gojenie ran
naturalny opatrunek
chitosan
colloidal silver
hyaluronic acid
wound healing
natural wound dressings
Opis:
Chitozan jest jednym z naturalnych polimerów, które stanowią bardzo obiecujące źródło do opracowywania preparatów przyspieszających gojenie ran oraz przeciwdrobnoustrojowych. Otrzymywany jest przez deacetylację chityny – jednego z najbardziej dostępnych surowców naturalnych, a także odpadu z przemysłu owoców morza. Chitozan jest biokompatybilny ze skórą, biodegradowalny, nietoksyczny. Dzięki właściwościom łatwego przygotowania, działania przeciwbakteryjnego i hemostatycznego ma zdolności do wspomagania regeneracji skóry. Funkcjonalne opatrunki na rany chitozanu i jego pochodnych cieszą się dużym zainteresowaniem ze względu na ich skuteczność i mechanizmy sprzyjania gojeniu ran skóry. Preparaty z chitozanem mogą być stosowane na rany ostre oraz przewlekłe, np. wrzody czy oparzenia. Wzbogacane często są innymi składnikami regenerującymi i przeciwdrobnoustrojowymi, np. kwasem hialuronowym czy srebrem koloidalnym. Skóra jest największym organem ludzkim, który może wynosić nawet 10% całkowitej masy ciała. Stanowi barierę ochronną przed środowiskiem, odpowiada za termoregulację i homeostazę płynów, pełni funkcję sensoryczną i immunologiczną. W przypadków niewielkich urazów organizm jest w stanie przywrócić integralność skóry z minimalną blizną w procesie wieloetapowym.
Chitosan is one of the natural polymers that are a very promising source for the development of wound healing and antimicrobial preparations. It is obtained by deacetylating chitin - one of the most available natural resources, as well as waste from the seafood industry. Chitosan is biocompatible with the skin, biodegradable and non-toxic. Due to the properties of easy preparation, antibacterial and haemostatic properties, and the ability to support skin regeneration, functional wound dressings of chitosan and its derivatives are of great interest due to their effectiveness and mechanisms of promoting skin wound healing. Chitosan preparations can be used for acute and chronic wounds like ulcers or burns. They are often enriched with other regenerating and antimicrobial ingredients, such as hyaluronic acid or colloidal silver.
Źródło:
Lek w Polsce; 2022, 370, 03; 7-12
2353-8597
Pojawia się w:
Lek w Polsce
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-9 z 9

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