- Tytuł:
- Studies of gentamycin adsorption on chitosan
- Autorzy:
-
Meler, Jan
Grimling, Bożena
Pluta, Janusz - Powiązania:
- https://bibliotekanauki.pl/articles/1035211.pdf
- Data publikacji:
- 2013
- Wydawca:
- Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
- Tematy:
-
Gentamycin
adsorption
chitosan - Opis:
- Chitosan as a dietary supplement has been used in the treatment of obesity due to its capability of binding bioactive compounds. A molecule of a cationic polymer, such as chitosan, may bind gentamycin. The aim of the study was to determine the binding capability of Gentamycin by chitosan’s contained in weight-loss supplements. The Gentamycin absorption was investigated by means of a dynamic method in a biopharmaceutical model imitating in vitro conditions including the required level of nutrients. Mean absorption of gentamycin by chitosan ranged from 2,1% to 34,1% depending on the environmental pH. The highest absorption rate was observed at above pH 6,8. Concluding, the studies confirmed that the investigated gentamycin interact with chitosan, what leads to decrease in their amount and affects the bioavailability of the drugs.
- Źródło:
-
Progress on Chemistry and Application of Chitin and its Derivatives; 2013, 18, 18; 175-179
1896-5644 - Pojawia się w:
- Progress on Chemistry and Application of Chitin and its Derivatives
- Dostawca treści:
- Biblioteka Nauki