- Tytuł:
- Strength, Water Absorption, Thermal and Antimicrobial Properties of a Biopolymer Composite Wound Dressing
- Autorzy:
-
Odili, Cletus Chiosa
Sekunowo, Olatunde Israel
Ilomuanya, Margaret Okonawan
Gbenebor, Oluwashina Philips
Adeosun, Samson Oluropo - Powiązania:
- https://bibliotekanauki.pl/articles/2056037.pdf
- Data publikacji:
- 2022
- Wydawca:
- Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Wydawnictwo AGH
- Tematy:
-
chitin
chitosan
hydrophilicity
polylactide acid
skin
wound
staphylococcus-Auerus - Opis:
- Conventional wound material allows bacterial invasions, trauma and discomfort associated with the changing of the dressing material, and the accumulation of body fluid for wounds with high exudate. However, there is a shift from conventional wound dressing materials to polymeric nanofibers due to their high surface area to volume ratio, high porosity, good pore size distribution, which allows for cell adhesion and proliferation. There is an urgent need to synthesis a biodegradable composite that is resistant to bacterial infection. In this study, an electrospun polylactide (PLA) composite suitable for wound dressing, with enhanced antimicrobial and mechanical properties, was produced. The neat PLA, PLA/CH (10 wt.%), PLA/CH (5 wt.%), PLA/CHS (10 wt.%), PLA/CHS (5 wt.%), PLA/CH (2.5 wt.%) /CHS (2.5 wt.%) and PLA/CH (5 wt.%)/CHS (5 wt.%), were electrospun using 0.14 g/ml solution. Results show that crystallinity (67.6%) of neat PLA declined by 3.8% on the addition of 2.5 wt.% chitin/chitosan with improved hydrophilicity of the composite. The tensile strength of neat PLA (0.3 MPa) increased (0.6 MPa) with 2.5 wt.% chitin/chitosan addition. The slight increase in the glass transition temperature from 75°C for neat PLA to 78°C of the composite fibre, showed improved ductility. The fibres showed little beads, hence suitable for wound dressing. The electrospun mats have good water absorption capacity and strong resistance against Staphylococcus aureus. Good performance was attained at 5 wt.% of chitin, chitosan and hybrid reinforcements. Therefore, a PLA/chitin/chitosan composite is recommended as a wound dressing material.
- Źródło:
-
Journal of Casting & Materials Engineering; 2022, 6, 1; 22--32
2543-9901 - Pojawia się w:
- Journal of Casting & Materials Engineering
- Dostawca treści:
- Biblioteka Nauki
Artykuł