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Wyszukujesz frazę "oncology" wg kryterium: Temat


Wyświetlanie 1-11 z 11
Tytuł:
A role of ghrelin in cancerogenesis
Autorzy:
Majchrzak, K.
Szyszko, K.
Pawlowski, K.M.
Motyl, T.
Krol, M.
Powiązania:
https://bibliotekanauki.pl/articles/31726.pdf
Data publikacji:
2012
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
ghrelin
cancerogenesis
growth hormone secretagogue receptor
cancer
mammary cancer
veterinary oncology
oncology
dog
animal disease
Opis:
Ghrelin is a 28 amino-acid multi-functional peptide hormone, which was identified as a natural ligand of the growth hormone secretagogue receptor (GHS-R). Pituitary growth hormone-releasing activity in both animals and humans has been well documented. It has various biological functions, including regulation of appetite and body weight, control of energy homeostasis, modulation of cardiovascular and gastrointestinal system and anti-inflammatory effect. However, both ghrelin and its receptor (GHS-R) are widely distributed in various tumors, which strongly implies their role in neoplastic cell growth trough autocrine/paracrine mechanism. Multiple studies have demonstrated the role of ghrelin in cancer cells proliferation, differentiation, invasiveness and apoptosis inhibition. The ghrelin axis is more complex than it was originally thought and consist of several compounds that might interact with each other and affect ghrelin activities. Here, we provide an overview of the ghrelin and its receptor role in tumor progression.
Źródło:
Polish Journal of Veterinary Sciences; 2012, 15, 1
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
On becoming a mother after cancer survival: a comprehensive literature review
Autorzy:
Sousa, Helena
Castro, Sónia
Pereira, M. Graça
Powiązania:
https://bibliotekanauki.pl/articles/2047212.pdf
Data publikacji:
2021-07-13
Wydawca:
Medical Education
Tematy:
cancer
oncology
fertility
motherhood
survivorship
review
Opis:
Problem identification: The desire for motherhood is one of the top priorities for most female young cancer survivors. The risk of infertility after cancer therapy is an important concern with several physical and emotional consequences. This comprehensive literature review aims to summarize and contextualize recent research that has been carried out on female fertility after cancer, suggesting future research and clinical directions. Literature search: Searches included the keywords “cancer”, “female”, “adults”, and “fertility”. Studies were selected if focused on infertility issues in female cancer survivors. Data synthesis: Eight themes were identified: the effects of anticancer treatments on fertility; fertility preservation methods; international recommendations regarding infertility risk; health professionals’ attitudes towards fertility preservation; patient’s concerns regarding the risk of infertility; patients' information needs; and the impact of the risk of infertility in patient’s quality of life. Conclusions: Psycho-oncologists should be integrated in the oncofertility teams to assess patients’ needs before cancer treatment initiation.
Źródło:
OncoReview; 2021, 11, 2; 48-55
2450-6125
Pojawia się w:
OncoReview
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Seizure as first manifestation of endocarditis in a patient with metastatic pancreatic adenocarcinoma: a case report
Autorzy:
Ciuffo Almeida, Marcel Pina
Santos da Silva Costa, Isabela Bispo
Feres de Almeida, Maria Carolina
Bittencourt Viana Cruz, Cecília Beatriz
Itala Rizk, Stéphanie
Abrahão Hajjar, Ludhmila
Powiązania:
https://bibliotekanauki.pl/articles/1035676.pdf
Data publikacji:
2019
Wydawca:
Medical Education
Tematy:
cancer
cardio-oncology
nonbacterial thrombotic endocarditis
Opis:
Nonbacterial thrombotic endocarditis is a potentially overlooked condition that involves the formation of sterile fibrin vegetations on heart valve leaflets in cancer patients. This condition can lead to valvular dysfunction, heart failure and systemic embolization. The pathogenesis depends on hypercoagulable states which are common in malignancy scenarios. Diagnosis requires the presence of valvular vegetations and the absence of infection.
Źródło:
OncoReview; 2019, 9, 4; 92-95
2450-6125
Pojawia się w:
OncoReview
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The small neuroendocrine intestine tumor as the cause of acute gastrointestinal obstruction and diffuse peritonitis – case report
Autorzy:
Łanowy, Patrycja
Bichalski, Miłosz
Waniczek, Dariusz
Bichalska-Lach, Magda
Dzindzio, Jakub
Powiązania:
https://bibliotekanauki.pl/articles/1062793.pdf
Data publikacji:
2019
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
GEP-NETs
NET
cancer
intestinal obstruction
oncology
surgery
tumor
Opis:
NET is a group of mostly malignant neoplasms with neuroendocrine differentiation. NET tumors are usually located in the small bowel (sbNET), in most cases their symptoms are the non-specific and surgical treatment of this pathogenic lesions is usually planned. Currently used classification of this group of tumors was created World Health Organization and is based on the rank expression of the Ki-67 (the mitotic index), angioinvasion and size of the tumor. GEP-NETs (gastroenteropancreatic neuroendocrine tumors) are known for expressing specific extracellular markers, such as synaptophysin and chromogranin A (CgA), which are used in a diagnostic process and can be detected with immunohistochemistry methods. The occurrence of clinical symptoms only at the advanced stage of the tumor development explains a low rate of life expectancy. At present, surgical removal of the tumor is the most effective treatment method. This case report describes a 67-year-old female with acute symptoms of gastrointestinal obstruction, complicated with acute peritonitis, who was diagnosed with sbNET during an ad hoc treatment.
Źródło:
World Scientific News; 2019, 133; 204-215
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Psychometric Properties of a Polish Version of the Parenting Concerns Questionnaire Among Parents With Cancer
Autorzy:
Matuszczak-Świgoń, Joanna
Powiązania:
https://bibliotekanauki.pl/articles/31343457.pdf
Data publikacji:
2023
Wydawca:
Katolicki Uniwersytet Lubelski Jana Pawła II. Towarzystwo Naukowe KUL
Tematy:
cancer
oncology
Parenting Concerns Questionnaire
parents with cancer
validation study
Opis:
In this study, I investigated parenting concerns and worries in parents during cancer treatment and examined the psychometric properties of the Polish version of the Parenting Concerns Questionnaire. Reliability, as well as factorial and convergent validity, were analyzed. A total sample size of 145 parents during cancer treatment (parents of children aged 18 years or younger at the time of the survey) participated in the study. The study was an online survey method conducted between January 2019 and December 2021. Parents were sent a survey link and were requested to fill the Perceived Stress Scale (PSS-10), the Parenting Stress Index (PSI-3-SF), the SF-36v2 Health Survey (SF-36v2), and the Family Resilience Assessment Scale (FRAS). The author received permission for using these questionnaires in online research. Confirmatory factor analysis of the Polish version of the Parenting Concerns Questionnaire did not confirm the original three-factor structure. However, the standardized factor loadings for the three factors were moderate to high. Additionally, apart from high-reliability estimates, this instrument proved to have good convergent and discriminant validity for all three factors. The PCQ-PL demonstrated adequate convergent validity with expected correlations with parenting stress, perceived stress, quality of life, and family resilience. The results suggest that the PCQ-PL is a reliable and relatively valid measurement tool to evaluate the level of parental concerns in Polish patients. The PCQ can be a useful tool to recognize parents with cancer who might need psychological support regarding combining the role of a parent and oncological patient.
Źródło:
Roczniki Psychologiczne; 2023, 26, 3; 291-310
1507-7888
Pojawia się w:
Roczniki Psychologiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Onkologopedia w systemie kształcenia logopedów
Oncological Logopaedics In The System Of Speech Therapists’ Education
Autorzy:
Hamerlińska, Agnieszka
Powiązania:
https://bibliotekanauki.pl/articles/695853.pdf
Data publikacji:
2018
Wydawca:
Uniwersytet Łódzki. Wydawnictwo Uniwersytetu Łódzkiego
Tematy:
logopedia
onkologopedia
rak
system kształcenia
speech therapy
oncology
cancer
education system
Opis:
In the beginning, the outline of speech therapy development and the process of institutionalization of the speech therapy in Poland will be characterized. This was done because oncology, a new speech therapy specialty, is the result of many years of speech therapy as a science. Next, the subject of oncologopedy research was described and the results of research on the attitudes of speech therapists towards speech therapy and speech disorders and primary activities caused by cancere were presented. It can be assumed that inclusion of oncologopedy in the vocational education of speech therapists, is an important direction in the development of science.
Onkologopedia, nowa specjalność logopedyczna, jest wynikiem wieloletniego kształtowania się logopedii jako nauki. W artykule przedstawiono zarys rozwoju logopedii oraz proces instytucjonalizacji zawodu logopedy w Polsce. Następnie opisano przedmiot badań onkologopedii i przedstawiono wyniki badań dotyczących postaw logopedów wobec terapii logopedycznej osób z zaburzeniami mowy i czynności prymarnych o podłożu choroby nowotworowej. Przyjąć można, że włączenie w system kształcenia logopedów przedmiotów z zakresu onkologopedii jest istotnym kierunkiem rozwoju nauki.
Źródło:
Logopaedica Lodziensia; 2018, 2; 49-61
2544-7238
2657-4381
Pojawia się w:
Logopaedica Lodziensia
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The role of E2F2 in signaling pathways associated with cancer pathogenesis and potential treatment: A review of current studies
Autorzy:
Domańska, Julia
Poboży, Kamil
Domański, Paweł
Fudalej, Marta
Deptała, Andrzej
Badowska-Kozakiewicz, Anna
Powiązania:
https://bibliotekanauki.pl/articles/22792539.pdf
Data publikacji:
2023-07
Wydawca:
Medical Education
Tematy:
E2F2
E2F
cancer
transcription factor
oncology
p53
p21
Opis:
Introduction and objective. E2F transcription factor 2 (E2F2) protein is the transcription factor that plays an important role in tumorigenesis. E2F2 effects the cell cycle, tumor suppressor proteins, and can also be transformed by proteins of small DNA tumor viruses. The objective of the study is to provide a summary of the current knowledge on the neoplastic pathways that involve E2F2. State of knowledge. Numerous studies have demonstrated a role for E2F2 in various signaling pathways. Certain components of these pathways may serve as potential targets for oncological therapy. E2F2 has been shown to be associated with neoplasms of various locations and histological types (breast, colon, gastric, laryngeal, liver, lung, ovarian, pancreatic, and prostate cancers). Conclusions. Further investigations of E2F2 pathways are warranted for a clearer understanding of neoplastic processes and to identify novel pharmacological treatments.
Źródło:
OncoReview; 2023, 13, 2; 58-66
2450-6125
Pojawia się w:
OncoReview
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
DNA microarrays - future in oncology research and therapy
Autorzy:
Krol, M.
Pawlowski, K.M.
Otrebska, D.
Motyl, T.
Powiązania:
https://bibliotekanauki.pl/articles/3349.pdf
Data publikacji:
2008
Wydawca:
Instytut Medycyny Wsi
Tematy:
DNA microarray
future
oncology
research
therapy
genomics
gene expression
canine mammary cancer
tumour
human disease
cancer
Źródło:
Journal of Pre-Clinical and Clinical Research; 2008, 02, 2
1898-2395
Pojawia się w:
Journal of Pre-Clinical and Clinical Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Neoplastic lesions in slaughter animals in Warminsko-Mazurskie voivodship (Poland) area during the years 2001-2007
Autorzy:
Radkowski, M.
Siemionek, J.
Zdrodowska, B.
Powiązania:
https://bibliotekanauki.pl/articles/30241.pdf
Data publikacji:
2010
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
slaughter animal
Polska
Warmia-Mazury voivodship
cattle
pig
post-slaughter examination
Polish Veterinary Inspection
animal disease
oncology
cancer
Opis:
During the period of 7 years, 2001-2007, 110,273 heads of cattle and 3,055,654 heads of pigs were examined by veterinarians of the Polish Veterinary Inspection in Warmińsko-Mazurskie voivodship. As a result of pre- and post-slaughter examination, 311 heads of cattle and 23 heads of pigs representing 0.279% and 0.00075% of the population respectively were considered unsuitable due to neoplastic lesions. The most frequently found lesions in cattle were fibroneuromas, neuromas and liposarcomas while in case of pigs those were various types of sarcomas, fibromas, cancers, nephromas and melanomas.
Źródło:
Polish Journal of Veterinary Sciences; 2010, 13, 4
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Analysis of changes in cancer health care system in Poland since the socio-economic transformation in 1989
Autorzy:
Dudek-Godeau, D.
Kieszkowska-Grudny, A.
Kwiatkowska, K.
Bogusz, J.
Wysocki, M.J.
Bielska-Lasota, M.
Powiązania:
https://bibliotekanauki.pl/articles/873636.pdf
Data publikacji:
2016
Wydawca:
Narodowy Instytut Zdrowia Publicznego. Państwowy Zakład Higieny
Tematy:
change analysis
human disease
cancer
health care system
Polska
socioeconomic transformation
oncology
CanCon network
Comprehensive Cancer Centres Network
Opis:
Background. The transformation period in Poland is associated with a set of factors seen as ‘socio-economic stress’, which unfavourably influenced cancer treatment and slowed down the progress of the Polish cancer care in the 90’s. These outcomes in many aspects of cancer care may be experienced till today. The results of the international EUROCARE and CONCORD studies based on European data prove evidence that there is a substantial potential for improvement of low 5-year survival rates in Poland. Since high survivals are related to notably efficient health care system, therefore, to improve organization and treatment methods seems to be one of the most important directions of change in the Polish health care system. Till today, cancer care in Poland is based on a network outlined by Professor Koszarowski in the middle of the last century, and is a solid foundation for the contemporary project of the Comprehensive Cancer Care Network (CCCN) proposed in the frame of CanCon Project. Objective. Analysis of the structure of health care system and the changes introduced within the network of oncology in Poland since the beginning of the post-commuinist socio-economic transformation in 1989. Materials and Methods. This study was conducted based on the CanCon methods aimed at reviewing specialist literature and collecting meaningful experiences of European countries in cancer care, including the main legal regulations. Results. The analysis provided evidence that the political situation and the economic crisis of the Transformation period disintegrated the cancer care and resulted in low 5-year survival rates. A step forward in increasing efficiency of the cancer treatment care was a proposal of the ’Quick Oncological Therapy’ together with one more attempt to organize a CCCN. With this paper the Authors contribute to the CanCon Project by exploration, analysis and discussion of the cancer network in Poland as an example of existing net-like structures in Europe as well as by preparation of guidelines for constructing a contemporary CCCN. Conclusions. (1) ‘Socio-economic’ stress adversely affected the efficiency of oncological treatment, both by reducing safety and slowing down the development of modern oncology. (2) Changing the current system into the contemporary form - CCCN could be an important step forward to optimise the oncological health care in Poland. (3) Introduction of the mandatory monitoring of organizational changes with the use of health standardized indicators could allow for the assessment of the effectiveness of implemented solutions and their impact on better prognosis for cancer patients. (4) Optimising the organization of the health care system is possible only by implementing necessary legislative corrections.
Wprowadzenie. Okres Transformacji w Polsce wiąże się z wieloma czynnikami postrzeganymi jako „stres społeczno- -gospodarczy”, które niekorzystnie wpłynęły na efekty leczenia nowotworów oraz spowolniły postęp w polskim lecznictwie onkologicznym w latach ‚90, co w wielu jego aspektach jest odczuwane do dziś. Wyniki międzynarodowych badań EUROCARE i CONCORD dowodzą, że wskaźniki 5-letnich przeżyć w Polsce mogą być znacząco wyższe. Wysokie wskaźniki 5-letnich przeżyć zależą od efektywnego systemu ochrony zdrowia, dlatego, poprawa organizacji i leczenia nowotworów, jest jednym z najważniejszych kierunków zmian w polskim systemie opieki zdrowotnej. System opieki onkologicznej w Polsce jest oparty na modelu sieci onkologicznej, której budowę w połowie ubiegłego stulecia rozpoczął Profesor Koszarowski. Stanowi on nadal solidny fundament do rozwoju nowoczesnej koncepcji sieci wielodyscyplinarnych centrów onkologii (ang. Comprehensive Cancer Care Network - CCCN) zaproponowanej w ramach projektu CanCon. Cel. Analiza struktury lecznictwa i zachodzących zmian w ramach sieci onkologicznej w Polsce po rozpoczęciu w 1989 postkomunistycznej transformacji społeczno-ekonomicznej po 1989 roku. Materiał i metody. Badanie zostało przeprowadzone w oparciu o metody przyjęte przez CanCon, tj. przegląd literatury specjalistycznej i analizę doświadczeń krajów europejskich w zakresie opieki onkologicznej, ze szczególnym uwzględnieniem polskich regulacji prawnych. Wyniki. Analiza wykazała, że sytuacja polityczna i kryzys gospodarczy w okresie Transformacji przyczyniły się do dezintegracji leczenia onkologicznego, a w efekcie złych wskaźników 5-letnich przeżyć. Analiza ta stanowi wkład Autorów do projektu CanCon poprzez analizę i omówienie sieci onkologicznej w Polsce, jako przykładu istniejących „podobnych do sieci” struktur lecznictwa w Europie. Zostanie ona wykorzystana przy opracowaniu wytycznych dotyczących współczesnej koncepcji CCCN. Postępem w zakresie organizacji leczenia onkologicznego w Polsce jest wdrożenie tzw. „Szybkiej Terapii Onkologicznej” oraz ponowna próba zorganizowania lecznictwa onkologicznego w ramach CCCN. Wnioski. (1) Stres społeczno-gospodarczy niekorzystnie wpływa na rokowanie u chorych na raka, zarówno poprzez obniżenie poczucia bezpieczeństwa socjalnego, jak i spowolnienie rozwoju nowoczesnej onkologii. (2) Zmiana obecnego systemu w nowoczesną formę - CCCN byłaby istotnym krokiem w stronę optymalizacji lecznictwa onkologicznego w Polsce. (3) Wprowadzenie obowiązku monitorowania zmian organizacyjnych, przy użyciu standaryzowanych wskaźników zdrowotnych w lecznictwie onkologicznym pozwoliłoby na ocenę skuteczności zastosowanych rozwiązań i ich wpływu na poprawę rokowania u pacjentów chorych na raka. (4) Optymalizacja organizacji systemu opieki zdrowotnej nie jest możliwa bez wprowadzenia koniecznych zmian legislacyjnych.
Źródło:
Roczniki Państwowego Zakładu Higieny; 2016, 67, 4
0035-7715
Pojawia się w:
Roczniki Państwowego Zakładu Higieny
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Lay beliefs on Polish oncology in the evaluation of healthy individuals
Autorzy:
Synowiec-Piłat, Małgorzata
Powiązania:
https://bibliotekanauki.pl/articles/986955.pdf
Data publikacji:
2017
Wydawca:
Instytut Medycyny Wsi
Tematy:
sociology of health and illness
lay perspective
medical institutions
oncology
cancer
lay referral system
medical knowledge
fear of cancer
Opis:
Introduction. Poland is among the countries which reported the highest rates of mortality from cancer. The health behaviours of people are influenced, among other things, by their beliefs about cancer, but their evaluation of oncological institutions and specialists seems also to be of great importance. Objectives. 1. How the respondents evaluate Polish oncology: a) the conditions of treatment in oncology hospitals, b) access to oncological medical services, c) the competence of oncologists. 2. What are the socio-cultural factors of the assessment of Polish oncology? 3. What is the influence of the grade level of the assessment of Polish oncology on the degree of fear and the knowledge about cancer? Materials and method. The study was carried out with a sample of 910 adult residents of Wroclaw in south-west Poland. Quota sampling was used. An interview questionnaire was used as the method. Results. Analysis of the data showed a negative image of Polish oncology, according to the study participants: dissatisfaction with both treatment conditions and with access to medical services. Assessment of Polish oncology depends primarily on education, age and economic situation, as well as ‘family history of cancer’, and attitude towards doctors. The lower the rating of Polish oncology, the lower the medical knowledge, and the higher the level of fear of cancer. Conclusions. Negative assessment of Polish oncology perpetuates the fear of cancer in society. There is a need for constant improvement of the quality of medical oncology services, for building public trust in physicians, to fight inequalities in health, and to take into account the lay perspectives in developing strategies to combat cancer.
Źródło:
Annals of Agricultural and Environmental Medicine; 2017, 24, 4
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-11 z 11

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