Temat: molecular aspect - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: Oral squamous cell carcinoma (OSCC) - molecular, viral and bacterial concepts
Autorzy:: Polz-Gruszka, D.
Macielag, P.
Foltyn, S.
Polz-Dacewicz, M.
Powiązania:: https://bibliotekanauki.pl/articles/3323.pdf
Data publikacji:: 2014
Wydawca:: Instytut Medycyny Wsi
Tematy:: human disease
cancer
oral squamous cell carcinoma
molecular aspect
viral aspect
bacterial concept
genetic abnormality aspect
epigenetic aspect
Opis:: Head and neck cancers constitute the sixth most common malignant tumours worldwide, and are one of the majors problems of global public health. In the oral cavity there are several types of oral cancers, but around 90% are squamous cell carcinoma. Many different risk factors play a role in the etiology of head and neck cancer. The aim of this study is presentation from the aspect of molecular, viral and bacterial infection. Knowledge about all factors which influence the development of these malignances is essential for diagnostics and successful treatment.
Źródło:: Journal of Pre-Clinical and Clinical Research; 2014, 08, 2
1898-2395
Pojawia się w:: Journal of Pre-Clinical and Clinical Research
Dostawca treści:: Biblioteka Nauki

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Tytuł:: Molecular and environmental aspects of skin cancers
Autorzy:: Zebracka, A.
Matysiak, M.
Dudra-Jastrzebska, M.
Kapka-Skrzypczak, L.
Powiązania:: https://bibliotekanauki.pl/articles/3509.pdf
Data publikacji:: 2015
Wydawca:: Instytut Medycyny Wsi
Tematy:: molecular aspect
environmental aspect
skin
cancer
malignant melanoma
basal cell carcinoma
squamous cell carcinoma
ultraviolet radiation
carcinogenesis
Opis:: Skin cancers are one of the most common cancers in the Caucasian population. A constantly increasing number of nonmelanoma skin cancers and malignant melanomas is observed. The incidence of skin cancers is associated mainly with exposure to sunlight. Therefore, agricultural workers who work in open spaces are a particularly vulnerable group. Currently, studies on the pathogenesis of skin cancer focus on the molecular basis associated with ultraviolet radiation. This study is an attempt to summarize the current state of knowledge on this issue. There have been demonstrated mutations in different classes of genes associated with carcinogenesis, including protooncogenes, tumour suppressor genes, genes that control apoptosis, genes encoding transcription factors and DNA repair genes in patients with skin cancers. Mutations in the latter result in reducing the effectiveness of DNA repair and fixation of mutations. All changes at the gene level lead to structural changes, quantitative and dysfunction of proteins encoded by these genes. All these factors contribute to the process of carcinogenesis. Due to increasing number of skin cancers, it seems important to increase knowledge of the molecular basis of skin cancers. This knowledge could be crucial for predicting the course of the disease, and for the development of new therapeutic strategies.
Źródło:: Journal of Pre-Clinical and Clinical Research; 2015, 09, 2
1898-2395
Pojawia się w:: Journal of Pre-Clinical and Clinical Research
Dostawca treści:: Biblioteka Nauki

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