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Wyszukujesz frazę "Tuberculosis" wg kryterium: Temat


Wyświetlanie 1-8 z 8
Tytuł:
Analysis of resistance to antimycobacterial drugs among MTBC strains isolated from cattle in Poland as a threat to human health
Analiza oporności na leki przeciwprątkowe wśród szczepów MTBC izolowanych od bydła w Polsce jako zagrożenie dla zdrowia ludzi
Autorzy:
Weiner, M.
Krajewska, M.
Zabost, A.
Augustynowicz-Kopeć, E.
Szulowski, K.
Powiązania:
https://bibliotekanauki.pl/articles/2048912.pdf
Data publikacji:
2020
Wydawca:
Akademia Bialska Nauk Stosowanych im. Jana Pawła II w Białej Podlaskiej
Tematy:
drug resistance
Mycobacterium tuberculosis
bovine tuberculosis
public health
antimicrobial
lekooporność
Mycobacterium tuberculosis complex
gruźlica bydlęca
zdrowie publiczne
leki przeciwprątkowe
Opis:
Background. Tuberculosis is a highly contagious disease affecting humans and animals. It is caused by mycobacteria that are part of the Mycobacterium tuberculosis complex (MTBC). The etiological agent causing bovine tuberculosis is mycobacteria bovis: Mycobacterium bovis and Mycobacterium caprae. According to the World Health Organization bovine tuberculosis is classified as direct zoonosis. Material and methods. The study material consisted of 129 MTBC strains isolated from Polish cattle, which were microbiologically analyzed. The resistance phenotype was tested for first-line anti-tuberculosis drugs used in the treatment of tuberculosis in humans. The drugs included streptomycin, isoniazid, rifampicin, ethambutol, and pyrazinamide. The MTBC strains tested in this study were isolated from cattle tissue post mortem so that the determination of drug resistance could meet only the epidemiological criterion. Results. Polish strains of mycobacteria bovis have not acquired environmental resistance despite the huge dynamics of changes in the phenotype of mycobacterial tuberculosis resistance. Strains classified as M. bovis are characterized by natural resistance to PZA, which is typical of this species. Conclusions. Drug resistance imposes the use of additional drugs. Drugs that are less effective than the basic drugs, drugs causing side effects more frequently and drugs that are much more expensive.
Wprowadzenie. Gruźlica jest wysoce zakaźną chorobą ludzi i zwierząt, którą powodują prątki wchodzące w skład kompleksu Mycobacterium tuberculosis (MTBC). Czynnikiem etiologicznym gruźlicy bydlęcej są prątki bydlęce: Mycobacterium bovis i Mycobacterium caprae. Zgodnie z klasyfikacją Światowej Organizacji Zdrowia, gruźlica typu bydlęcego zaliczana jest do zoonoz bezpośrednich. Materiał i metody. W pracy poddano analizie mikrobiologicznej 129 szczepów MTBC wyizolowanych od bydła w Polsce. Fenotyp oporności zbadano pod kątem leków przeciwprątkowych pierwszej linii stosowanych w leczeniu gruźlicy u ludzi: streptomycyny, izoniazydu, rifampicyny, etambutolu i pyrazynamidu. Szczepy MTBC badane w niniejszej pracy wyizolowano z tkanek bydła pobranych post mortem, tak że oznaczenie lekooporności w tym zadaniu spełniło jedynie kryterium epidemiologiczne. Wyniki. Polskie szczepy prątka bydlęcego nie nabyły oporności środowiskowej. Szczepy sklasyfikowane jako M. bovis cechują się charakterystyczną dla tego gatunku naturalną opornością na PZA. Wnioski. Wystąpienie lekooporności zmusza do stosowania leków dodatkowych, mniej skutecznych niż leki podstawowe i powodujących częściej objawy uboczne, a jednocześnie znacznie droższych.
Źródło:
Health Problems of Civilization; 2020, 14, 1; 24-28
2353-6942
2354-0265
Pojawia się w:
Health Problems of Civilization
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Human as a potential vector of bovine tuberculosis in cattle
Autorzy:
Krajewska-Wedzina, M.
Weiner, M.
Anusz, K.
Augustynowicz-Kopeć, E.
Lipiec, M.
Szulowski, K.
Powiązania:
https://bibliotekanauki.pl/articles/2085020.pdf
Data publikacji:
2019
Wydawca:
Instytut Medycyny Wsi
Tematy:
bovine tuberculosis
Mycobacterium bovis
epidemiology
zoonosis
mycobacteriology
public health
transmission
tuberculosis
Opis:
Introduction and objective. Bovine tuberculosis (bTB, bovine TB) is caused by mycobacteria which are grouped within the MTBC. TB in animals is a highly infectious and progressive disease which can be transmitted to humans. Since 2009, Poland has gained official bTB-free status. Despite the official fact of bTB-free status, a dozen bTB outbreaks are still noted each year. Since 2000 in Poland, every year 1/5 of the national herd is subject to intradermal skin TB testing to control the bTB outbreaks in the cattle population. Application, with 5-year intervals between each government-funded skin test, undoubtedly resulted in financial savings. However it also seems to have caused several adverse and worrying events, e.g. an increase in the number of reactors detected and removed from a single tested herd. The objective of this study was the examination of 898 cattle imputed with bTB infection in Poland between 2008–2012. Materials and method. The study concerned a potential epidemic outbreak with suspected bTB transmission. 20 cows came from 3 herds in the same county located in the same province in southern Poland. Results. 134 MTBC strains were identified. In MIRU-VNTR, all isolates showed the same genetic pattern 322532243421232. Based on molecular investigation, the characteristics of M. bovis strains isolated from cattle from 3 different herds confirmed the common source of this zoonotic disease. Conclusions. Although not bacteriologically proven, everything points to the fact that humans were the vector of bovine tuberculosis transmission between herds. This finding confirms transmission between 3 cattle herds in the Małopolskie Province in southern Poland (Podhale). The outbreak of tuberculosis in animals finally compromised public health.
Źródło:
Annals of Agricultural and Environmental Medicine; 2019, 26, 3; 396-399
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
A case of bovine tuberculosis in pigs in Poland - a country free from the disease
Autorzy:
Lipiec, M.
Radulski, L.
Szulowski, K.
Powiązania:
https://bibliotekanauki.pl/articles/2082990.pdf
Data publikacji:
2019
Wydawca:
Instytut Medycyny Wsi
Tematy:
pigs
bovine tuberculosis
eradication
Opis:
Introduction. Bovine tuberculosis is a chronic contagious disease caused by Mycobacterium bovis or Mycobacterium caprae. Before widespread action conducted in Poland between 1959–1975 to combat bovine tuberculosis (BTB), about 40% of all tuberculosis cases in pigs was caused by the bovine bacillus. At the present time, correctly carried out, long-term control of cattle has resulted in cases of bovine tuberculosis in pigs and humans being extremely rare and sporadic. In pigs, tuberculosis is most often caught in a slaughterhouse during slaughter. Materials and method. Samples came from pigs kept on the farm. Traditional bacteriological methods on solid media (Stonebrink, LJ with pyruvate) supported by the semi-automatic, liquid indicative culture method (MGIT) and PCR test were applied in targeted studies. The GenoType Mycobacterium MTBC and CM tests (Hain Lifescience, Germany) were used to additionally confirm that isolated strains classification was used. Results. Strains of mycobacteria were isolated from all examined pigs. Mycobacterium bovis was determined by real time PCR and Hain Genotype methods. Conclusions. In order to effectively fight against BTB, all animals on farms should be tested, regardless of species, while the milk of suspected cows should be utilized without being used for feed. It is important to adapt the current legal regulations to the current epidemiological situation.
Źródło:
Annals of Agricultural and Environmental Medicine; 2019, 26, 1; 29-32
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Animal tuberculosis as a potential danger to men
Gruźlica zwierząt jako potencjalne zagrożenie dla człowieka
Autorzy:
Krajewska, M.
Weiner, M.
Augustynowicz-Kopeć, E.
Powiązania:
https://bibliotekanauki.pl/articles/2052645.pdf
Data publikacji:
2017
Wydawca:
Akademia Bialska Nauk Stosowanych im. Jana Pawła II w Białej Podlaskiej
Tematy:
Mycobacterium tuberculosis complex
bovine tuberculosis
public health
zoonosis
transmission
gruźlica bydlęca
zdrowie publiczne
zoonoza
transmisja
Opis:
Tuberculosis (latin: tuberculosis) is an infectious disease which affects man and many species of animals. The aetiological factor of tuberculosis are bacillus which belong to the Mycobacterium tuberculosis complex (MTBC) while their host preferences, gene sequence and the level of drug resistance can differ. MTBC constitute a morphologically and biochemically homogeneous group of bacteria which mainly spreads through the aerogenic channel on small, dry particles of phlegm called droplet nuclei which are discharged while infected people or animals cough. Infection occurs after predisposed individual inhales into his or her lungs the bacilli, where they easily multiply in the soft lungs tissue and cause infection. The World Health Organization (WHO) classified bovine tuberculosis (bTB) as direct zoonosis, in which case the transmission of disease is possible without the indirect host’s involvement. Moreover, bTB is the best example of anthroponosis, when the disease is transferred from animal to men. The possibility of dividing the strains of animal bacillus into the two genres: M. bovis and M. caprae raises some significant legal concerns in Europe since in many of its countries, including among others Poland, caprae is not considered to be an etiological factor of bTB.
Gruźlica (łac. tuberculosis) jest zakaźną chorobą ludzi i wielu gatunków zwierząt. Czynnikiem etiologicznym gruźlicy są prątki należące do Mycobacterium tuberculosis complex (MTBC), różniące się między sobą różnym powinowactwem do rodzaju gospodarza, sekwencjami w genach oraz cechami lekooporności. Stanowią niejednorodną grupę pod względem morfologicznym i biochemicznym. Prątki należące do kompleksu tuberculosis przenoszone są głównie drogą aerogenną na małych, wyschniętych cząstkach śluzu zwanych jądrami kropelek (droplet nuclei), które są wydzielane w czasie kaszlu chorych ludzi i zwierząt. Zakażenie następuje, gdy wrażliwy na zakażenie osobnik zaaspiruje prątki do płuc, gdzie w delikatnej tkance mogą się one rozmnażać dając początek infekcji. Zgodnie z klasyfikacją Światowej Organizacji Zdrowia (WHO) gruźlica bydlęca zaliczana jest do zoonoz bezpośrednich, gdzie przeniesienie czynnika infekcyjnego odbywa się bez pomocy żywicieli pośrednich. Ponadto gruźlica zwierząt jest najlepszym przykładem antropozoonozy, gdzie transmisja choroby możliwa jest ze zwierzęcia na człowieka. Możliwość różnicowania szczepów prątka bydlęcego na gatunki M. bovis i M. caprae rodzi w Europie istotne wątpliwości prawne, ponieważ w wielu krajach caprae nie widnieje jako czynnik etiologiczny gruźlicy bydlęcej, w tym m. in. w Polsce.
Źródło:
Health Problems of Civilization; 2017, 11, 1; 10-14
2353-6942
2354-0265
Pojawia się w:
Health Problems of Civilization
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Mycobacterium caprae - the first case of the human infection in Poland
Autorzy:
Kozińska, M.
Krajewska-Wędzina, M.
Augustynowicz-Kopeć, E.
Powiązania:
https://bibliotekanauki.pl/articles/2085343.pdf
Data publikacji:
2020
Wydawca:
Instytut Medycyny Wsi
Tematy:
bovine tuberculosis
Mycobacterium bovis
Mycobacterium caprae
zoonosis
Opis:
The strain of tuberculous mycobacteria called Mycobacterium caprae infects many wild and domestic animals; however, because of its zoonotic potential and possibility of transmission between animals and humans, it poses a serious threat to public health. Due to diagnostic limitations regarding identification of MTB strains available data regarding the incidence of M. caprae, human infection does not reflect the actual size of the problem. Despite the fact that the possible routes of tuberculosis transmission are known, the epidemiological map of this zoonosis remains underestimated. The progress in diagnostic techniques, application of advanced methods of mycobacterium genome differentiation and cooperation between scientists in the field of veterinary medicine and microbiology, have a profound meaning for understanding the phenomenon of bovine tuberculosis and its supervise its incidence. This is the first bacteriologically confirmed case of human infection of M. caprae in Poland.
Źródło:
Annals of Agricultural and Environmental Medicine; 2020, 27, 1; 151-153
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Suspicion of bovine tuberculosis in sheep in the Małopolskie Voivodeship (southern Poland)
Autorzy:
Didkowska, A.
Żmuda, P.
Orłowska, B.
Nowak, M.
Filip-Hutsch, K.
Cuper, K.
Krajewska-Wędzina, M.
Anusz, K.
Powiązania:
https://bibliotekanauki.pl/articles/16539333.pdf
Data publikacji:
2022
Wydawca:
Polska Akademia Nauk. Czasopisma i Monografie PAN
Tematy:
bovine tuberculosis
dairy products
IGRA
sheep
tuberculin skin test
Opis:
Bovine tuberculosis (BTB) in sheep (Ovis aries) is caused by Mycobacterium bovis and Mycobacterium caprae. Even though sheep have been considered less sensitive to BTB than other ruminants, they have been subject to increasing numbers of tuberculosis cases and it has been suggested that they may act as a disease reservoir in some regions. Aim of the study: Following a report of tuberculous-like gross lesions (repeated cases of purulent or caseous lymphadenitis and a single case of serosal tubercles on the peritoneum) from veterinarians working in a slaughterhouse in the Małopolskie Voivodeship, southern Poland, the aim of this study was to conduct ante-mortem BTB diagnostics in three flocks with suspected BTB. The animals for testing were selected randomly from the flocks; a blood sample for interferon-γ release assay (IGRA) and a single tuberculin skin test (TST) was performed on each sheep. All TST results were negative. The IGRA result was positive in two ewes from the same flock (four and five years of age); these two sheep were tested microbiologically using Stonebrink and Löwenstein-Jensen media. No gross lesions suggesting BTB were observed, and the culture results were negative. Based on the positive IGRA results, together with its high specificity in sheep, and the potential risk to humans posed by consuming local unpasteurized dairy products, we recommend introducing serological BTB screening in sheep from this area, and subjecting the positive results to confirmation by culture.
Źródło:
Polish Journal of Veterinary Sciences; 2022, 25, 3; 469-473
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Bovine tuberculosis outbreak in farmed American bison (Bison bison) in Poland
Autorzy:
Krajewska-Wędzina, M.
Olech, W.
Kozińska, M.
Augustynowicz-Kopeć, E.
Weiner, M.
Szulowski, K.
Powiązania:
https://bibliotekanauki.pl/articles/2087860.pdf
Data publikacji:
2017
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
Mycobacterium caprae
bovine tuberculosis
bison (Bison bison)
epidemiology
Źródło:
Polish Journal of Veterinary Sciences; 2017, 4; 819-821
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
A review of tuberculosis and parasitic disease co-infection in ungulates, with regard to the potential threat to European bison (Bison bonasus)
Autorzy:
Gałązka, M.
Didkowska, A.
Anusz, K.
Pyziel-Serafin, A.
Powiązania:
https://bibliotekanauki.pl/articles/16647526.pdf
Data publikacji:
2023
Wydawca:
Polska Akademia Nauk. Czasopisma i Monografie PAN
Tematy:
bovine tuberculosis
co-infection
Fasciola hepatica
helminths
Mycobacterium bovis
Mycobacterium caprae
parasites
Opis:
Bovine tuberculosis (BTB) is a dangerous zoonosis which presents a serious problem for endangered species such as European bison (Bison bonasus). Little is known about the influence of parasitic co-infections on the course and diagnosis of tuberculosis in animals. The best known co-infection in cattle is Fasciola hepatica and Mycobacterium bovis. The aim of this study was to review the most recent literature regarding tuberculosis and parasite co-infection in ungulates and relate the results to European bison. Our findings indicate that any comprehensive diagnosis of BTB should include parasitological monitoring, and the possible impact of such invasions on cellular response-based tuberculosis tests should be taken into account. The diagnosis of BTB is complex, as is its pathogenesis, and parasitic infestations can have a significant impact on both. This should be taken into account during further research and monitoring of tuberculosis in European bison.
Źródło:
Polish Journal of Veterinary Sciences; 2023, 26, 1; 155-161
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-8 z 8

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