- Tytuł:
- Metal-organic frameworks for efficient drug adsorption and delivery
- Autorzy:
-
Hyjek, Kornelia
Jodłowski, Przemysław - Powiązania:
- https://bibliotekanauki.pl/articles/35134841.pdf
- Data publikacji:
- 2023
- Wydawca:
- Radomskie Towarzystwo Naukowe
- Tematy:
-
drug delivery systems
metal-organic frameworks
synthesis
characterization
drug loading
biocompatibility
systemy dostarczania leków
sieć metalo-organiczna
synteza
charakterystyka
akumulacja leku
biokompatybilność - Opis:
- In recent years, the number of materials used as drug delivery systems (DDS) has increased dramatically. The widespread use of DDSs has improved both the safety and efficacy of therapy. The systems currently in use pose numerous drawbacks and require proper improvements. Although many modern materials are being developed, metal-organic frameworks (MOFs) deserve special attention. Thermal and chemical stability, high specific surface area, low toxicity, high biocompatibility, and great potential for modification are the main features enabling MOFs to be used as DDS. In this review, we describe MOFs, their structure, synthesis, and characterization, as well as drug loading, drug release kinetics, and bioassays. A critical approach is to outline the disadvantages as well as the limitations of MOFs and to identify areas that need to be studied more thoroughly. Nonetheless, the prospective nature of MOFs as DDS and potential adsorbents in overdose or poisoning is presented and highlighted.
- Źródło:
-
Scientiae Radices; 2023, 2, 2; 115-189
2956-4808 - Pojawia się w:
- Scientiae Radices
- Dostawca treści:
- Biblioteka Nauki
Artykuł