- Tytuł:
- Synthesis and characterization of fully substituted pyrimidines by using ketene dithioacetal as potent antimicrobial agent
- Autorzy:
-
Khunt, H. R.
Pipaliya, P. P.
Ghelani, S. M.
Babariya, J. S.
Naliapara, Y. T. - Powiązania:
- https://bibliotekanauki.pl/articles/412064.pdf
- Data publikacji:
- 2014
- Wydawca:
- Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
- Tematy:
-
ketene dithioacetal
pyrimidines
guanidine
biginelli reaction - Opis:
- Various ketene dithioacetals of acetoacetanilides were reacted with guanidine nitrate in the presence of base to produce the 2-amino-4-isopropyl-6-alkoxy-N-arylpyrimidine-5-carboxamide derivatives with good yields. All the synthesized compounds were characterized by mass, NMR and IR and also evaluated for antimicrobial activity against five different bacterial and fungal strains. The compounds 4i, 4k and 4l has found comparatively good active against all the bacterial strains.
- Źródło:
-
International Letters of Chemistry, Physics and Astronomy; 2014, 5; 134-141
2299-3843 - Pojawia się w:
- International Letters of Chemistry, Physics and Astronomy
- Dostawca treści:
- Biblioteka Nauki
Artykuł