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Wyświetlanie 1-4 z 4
Tytuł:
Oxidant - antioxidant balance in host - parasite relationship
Autorzy:
Hadas, E.
Boczon, K.
Powiązania:
https://bibliotekanauki.pl/articles/841174.pdf
Data publikacji:
1998
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
parasite
oxidant-antioxidant balance
enzyme
equilibrium
peroxide
free radical
antioxidant
oxidant
host-parasite relationship
oxidizing-antioxidizing equilibrium
Źródło:
Annals of Parasitology; 1998, 44, 3
0043-5163
Pojawia się w:
Annals of Parasitology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Double-edged sword behaviour of gallic acid and its interaction with peroxidases in human microvascular endothelial cell culture (HMEC-1). Antioxidant and pro-oxidant effects
Autorzy:
Serrano, José
Cipak, Ana
Boada, Jordi
Gonzalo, Hugo
Cacabelos, Daniel
Cassanye, Anna
Pamplona, Reinald
Zarkovic, Neven
Portero-Otin, Manuel
Powiązania:
https://bibliotekanauki.pl/articles/1040403.pdf
Data publikacji:
2010
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
gallic acid
peroxidase
pro-oxidant
antioxidant
HMEC-1
Opis:
A previous report from our group had shown in vitro a direct interaction between peroxidases and dietary antioxidants at physiological concentrations, where in the absence of H2O2, the antioxidants could serve as oxidizing substrates for the peroxidases. However, the physiological relevance of those findings had not been evaluated. The main objective of this study was to determine whether the oxidizing products produced in the interaction between peroxidase and gallic acid at a physiological concentration of 1 µM may promote cell death or survival in a human microvascular endothelial cell line (HMEC-1). Our findings suggested that gallic acid may show a double-edged sword behaviour, since in the absence of H2O2 it may have a pro-oxidant effect which may promote cell injury (evidenced by LDH, Crystal Violet and calcein AM viability/citotoxicity assays), while in the presence of H2O2, gallic acid may act as an antioxidant inhibiting oxidative species produced in the peroxidase cycle of peroxidases. These observations were confirmed with several oxidative stress biomarkers and the evaluation of the activation of cell survival pathways like AKT and MAPK/ERK.
Źródło:
Acta Biochimica Polonica; 2010, 57, 2; 193-198
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Antioxidant and antimicrobial potentials of mycelial extracts of Hohenbuehelia myxotricha grown in different liquid culture media
Autorzy:
Krupodorova, T.
Barshteyn, V.
Sevindik, M.
Powiązania:
https://bibliotekanauki.pl/articles/2096244.pdf
Data publikacji:
2022
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
antioxidant
oxidant
antimicrobial
ethanolic extracts
mycelium
Hohenbuehelia myxotricha
Opis:
In addition to their nutritional properties, mushrooms have emerged as a health supplement because of their medicinal potential. Many studies have shown that mushrooms exhibit important biological activities. Here, the antioxidant and antimicrobial activities of Hohenbuehelia myxotricha (Lév.) Singer mycelia cultivated on Sabouraud dextrose broth (SDB) and glucose peptone yeast (GPY) medium were studied. The total antioxidant status (TAS), total oxidant status (TOS), and oxidative stress index (OSI) of ethanolic extracts of mycelia were measured using Rel Assay kits. The antioxidant and oxidant potentials of H. myxotricha mycelial extracts were determined for the first time in the present study. The highest TAS, TOS, and OSI values of H. myxotricha were 5.416 ± 0.150 mmol/l, 1.320 ± 0.156 μmol/l, and 0.024 ± 0.003, respectively. Ethanolic mycelial extracts of H. myxotricha showed antimicrobial activities at concentrations from 25 to 200 μg/ml against all the studied bacteria (Acinetobacter baumannii, Enterococcus faecalis, Escherichia coli, Staphylococcus aureus, methicillin-resistant S. aureus, and Pseudomonas aeruginosa ) and fungi (Candida albicans, C. glabrata, and Issatchenkia orientalis ) tested by the agar dilution method. The antifungal activity of the extract was more significant than its antibacterial activity. The antioxidant, oxidant, and antimicrobial potentials of H. myxotricha mycelia varied depending on the culture media used. GPY medium was more suitable for the synthesis of antibiotic compounds against E. coli, while SDB medium was more appropriate for producing metabolites with antioxidant and antifungal properties. Based on the results, ethanolic extract of H. myxotricha mycelia showed a significant pharmacological potential and could be used as a natural antioxidative and antimicrobial source for health benefit.
Źródło:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2022, 103, 1; 19-28
0860-7796
Pojawia się w:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Biochemical aspects of the host defence mechanisms in experimental trichinellosis
Autorzy:
Boczon, K.
Hadas, E.
Derda, M.
Powiązania:
https://bibliotekanauki.pl/articles/840227.pdf
Data publikacji:
1997
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
host tissue
infection
tissue damage
trichinellosis
biochemical aspect
antioxidant
free radical
oxidant
Trichinella spiralis
host
Źródło:
Annals of Parasitology; 1997, 43, 3
0043-5163
Pojawia się w:
Annals of Parasitology
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-4 z 4

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