Temat: Oxidative stress - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: Study of antioxidant activity of liposomal forms of quercetin and curcumin in ischemic heart disease
Autorzy:: Pylypenko, D.
Gorbach, T.
Krasnopolsky, Y.
Powiązania:: https://bibliotekanauki.pl/articles/2096332.pdf
Data publikacji:: 2020
Wydawca:: Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:: curcumin
antioxidant
quercetin
liposomes
oxidative stress markers
Opis:: Quercetin and curcumin are plant polyphenolic antioxidants with proven pharmacological efficacy. Their use is, however, limited due to low bioavailability and oral administration route. The encapsulation of lipophilic compounds in liposomes enables to increase their bioavailability and to create an injectable form. The present study aimed to comparatively investigate the antioxidant activity of a complex liposomal preparation containing two lipophilic antioxidants (quercetin and curcumin) and their monopreparations in liposomal forms. This study was conducted on Wistar line rats with experimental model of ischemic heart disease. Oxidative stress markers such as total antioxidant activity, malondialdehyde, and peroxidized proteins were analyzed in blood serum and cardiac tissue. Ischemic heart disease is accompanied with lipid peroxidation and changes in the activity of the antioxidant system. The obtained results demonstrated the antioxidant activity of monopreparations of curcumin and quercetin and their complex in liposomal forms. Quercetin and curcumin showed different antioxidant activities in terms of oxidative stress markers. The complex of the two antioxidants showed the synergistic effect of their lipophilic compounds in liposomal forms, which led to the normalization of test parameters according to the level of the control sample.
Źródło:: BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2020, 101, 4; 273-282
0860-7796
Pojawia się w:: BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 2.

Tytuł:: Current Perspective About the Effect of a Ketogenic Diet on Oxidative Stress – a Review
Autorzy:: Drabińska, Natalia
Powiązania:: https://bibliotekanauki.pl/articles/28408453.pdf
Data publikacji:: 2024-03-07
Wydawca:: Instytut Rozrodu Zwierząt i Badań Żywności Polskiej Akademii Nauk w Olsztynie
Tematy:: ketogenic diet
oxidative stress
antioxidant
oxidation
lipids
Opis:: Oxidative stress (OS) plays a pivotal role in the development of many diseases. Therefore, many efforts have been undertaken to minimize the consequences of OS or improve antioxidant defence systems. One solution expected to improve redox homeostasis is the ketogenic diet (KD). KD is a low-carbohydrate, high-fat diet leading to a ketosis state. The shift in metabolism occurring in ketosis can affect the reactive oxygen species (ROS)-producing pathways and influence the expression of enzymes involved in redox homeostasis. Therefore, this review summarizes and discusses existing knowledge about KD and ROS homeostasis. The available tools for evaluating OS status are presented, listing their potential and drawbacks. An important aspect is the summary of the current knowledge about the effect of KD on OS conducted in vitro, in vivo, and in clinical trials. Finally, the review addresses future studies needed to understand the connection between KD and OS.
Źródło:: Polish Journal of Food and Nutrition Sciences; 2024, 74, 1; 92-105
1230-0322
2083-6007
Pojawia się w:: Polish Journal of Food and Nutrition Sciences
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 3.

Tytuł:: Mechanisms of interaction of selected environmental factors on the formation of pathophysiological changes in cataracts
Autorzy:: Kempka, Katarzyna
Kamiński, Piotr
Lorek, Małgorzata
Malukiewicz, Grażyna
Bogdzińska, Maria
Powiązania:: https://bibliotekanauki.pl/articles/1030797.pdf
Data publikacji:: 2020
Wydawca:: Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:: antioxidant
biotechnology
cataract
oxidative stress
reactive oxygen species
Opis:: Biotechnology is a relatively young interdisciplinary discipline of science. Thanks to her techniques, we can currently do a lot of research. Biotechnologists in cooperation with other scientists are trying to develop new standards that would become the future of treatment for many diseases, including cataracts. Today, cataracts are increasingly recognized as a civilization disease of the eyes. Unfortunately, if left untreated, it can lead to complete blindness. The etiology of this disease is complex and not fully understood. At present, its foundations are being sought to be able to diagnose her faster and to introduce appropriate treatment early. Literature data currently indicate that it can arise as a result of: age- related changes, genetic (congenital) conditions, inflammation, metabolic disorders, the effects of certain drugs, and complications of eye diseases. From the latest reports we learn that antioxidation can have positive effects when dissolving the protein directly affecting the formation of cataracts. Biotechnology has amazing opportunities to conduct research that can help bring closer the etiology of cataracts and start to treat the disease faster by which so many people in the world lose sight.
Źródło:: World Scientific News; 2020, 145; 115-127
2392-2192
Pojawia się w:: World Scientific News
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 4.

Tytuł:: Mercury induced oxidative stress of antioxidants in Clitoria ternatea L.
Autorzy:: Priya, M.
Balakrishnan, V.
Kiruthika Lakshmi, A.
Aruna, R.
Ravindran, K.C.
Powiązania:: https://bibliotekanauki.pl/articles/10952.pdf
Data publikacji:: 2014
Wydawca:: Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:: biofertilizer
enzyme
mercury
metal stress
oxidative stress
antioxidant
Clitoria ternatea
Opis:: Biofertilizers are the special formulation of specific beneficial microorganisms that promote the growth of plant crops by converting the unavailable form of nutrients into available form. Here, the effect of heavy metal stress on antioxidant enzymes were studied in Clitoria ternatea L. leaves. Clitoria ternatea L. plant was grown for 30 days and the heavy metal mercuric chloride was sprayed after 10 days from the date of planting. Effect of mercuric chloride was observed in treated plants. The selected plant Clitoria ternatea L. was grown under mercuric chloride treatment in a specified concentration 1 μg/10 ml. The control plant maintained without the treatment of mercuric chloride. Antioxidant effect of mercuric chloride was measured under controlled and treated conditions. The selected plant Clitoria ternatea L. was grown under mercuric chloride in treatment. Further it increases H2O2 content and the antioxidant enzyme activities such as superoxide dismutase (SOD), catalase (CAT), and peroxidase (POD) were observed in mercuric chloride treated plants when compared with control. Here mercuric chloride was accumulated more in matured leaves. The results are discussed with the literature.
Źródło:: International Letters of Natural Sciences; 2014, 18
2300-9675
Pojawia się w:: International Letters of Natural Sciences
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 5.

Tytuł:: Melatonin and its metabolites: new findings regarding their production and their radical scavenging actions
Autorzy:: Reiter, Russel
Tan, Dun-xian
Terron, M
Flores, Luis
Czarnocki, Zbigniew
Powiązania:: https://bibliotekanauki.pl/articles/1041101.pdf
Data publikacji:: 2007
Wydawca:: Polskie Towarzystwo Biochemiczne
Tematy:: electron donation
melatonin synthesis
free radicals
antioxidant
oxidative stress
Opis:: This review summarizes some of the recent findings concerning the long-held tenet that the enzyme, N-acetyltransferase, which is involved in the production of N-acetylserotonin, the immediate precursor of melatonin, may in fact not always control the quantity of melatonin generated. New evidence from several different laboratories indicates that hydroxyindole-O-methyltransferase, which O-methylates N-acetylserotonin to melatonin may be rate-limiting in some cases. Also, the review makes the point that melatonin's actions are uncommonly widespread in organs due to the fact that it works via membrane receptors, nuclear receptors/binding sites and receptor-independent mechanisms, i.e., the direct scavenging of free radicals. Finally, the review briefly summarizes the actions of melatonin and its metabolites in the detoxification of oxygen and nitrogen-based free radicals and related non-radical products. Via these multiple processes, melatonin is capable of influencing the metabolism of every cell in the organism.
Źródło:: Acta Biochimica Polonica; 2007, 54, 1; 1-9
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 6.

Tytuł:: The role of metal ions in biological oxidation - the past and the present
Autorzy:: Kleczkowski, M.
Garncarz, M.
Powiązania:: https://bibliotekanauki.pl/articles/30753.pdf
Data publikacji:: 2012
Wydawca:: Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:: metal ion
oxidative stress
biological oxidation
prooxidant
antioxidant
pathological process
Opis:: Two theories, one based on the metabolism of inorganic substances, the other on metabolism of organic substances, have played an important role in the explanation of the origin of life. They demonstrate that the original environment of life on Earth was seawater containing micronutrients with structural, metabolic and catalytic activity. It is assumed that the first primitive organisms lived around 3.8 billion years ago and it was also then that the first catalytic reaction involving metal ions occurred. Biological oxidation leading to oxidative stress and cell damage in animals represents one of these types of reactions which are responsible for many animal diseases. The role of prooxidative and antioxidative actions of transition metal ions as well as their neuropathological consequences have therefore been the topic for many research projects. There is hope that metal chelates and antioxidants might prove to be a modern mode of therapy for i.e. neurogenerative diseases. The aim of this review is to show the evolution of scientific knowledge on metal ions, their biological oxidation, and an overview of their role in physiology and in pathological processes.
Źródło:: Polish Journal of Veterinary Sciences; 2012, 15, 1
1505-1773
Pojawia się w:: Polish Journal of Veterinary Sciences
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 7.

Tytuł:: Towards understanding vacuolar antioxidant mechanisms
Autorzy:: Peshev, D.
Vergauwen, R.
Hideg, E.
Van den Ende, W.
Powiązania:: https://bibliotekanauki.pl/articles/80706.pdf
Data publikacji:: 2013
Wydawca:: Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:: conference
plant
abiotic stress
reactive oxygen species
scavenging
antioxidant
oxidative stress
hydroxyl radical
Źródło:: BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2013, 94, 2
0860-7796
Pojawia się w:: BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 8.

Tytuł:: Novel roles for glutathione in linking oxidative stress to phytohormone-dependent signalling
Autorzy:: Noctor, G.
Han, Y.
Chaouch, S.
Mhamdi, A.
Powiązania:: https://bibliotekanauki.pl/articles/80088.pdf
Data publikacji:: 2013
Wydawca:: Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:: conference
glutathione
oxidative stress
phytohormone
antioxidant
protein structure
protein function
signalling
Źródło:: BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2013, 94, 2
0860-7796
Pojawia się w:: BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 9.

Tytuł:: NADPH oxidase C is not the main source of ROS under arsenic toxicity but regulates antioxidants and metal transporters
Autorzy:: Gupta, D.
Inouhe, M.
Rodriguez-Serrano, M.
Romero-Puertas, M.
Sandalio, L.
Powiązania:: https://bibliotekanauki.pl/articles/81189.pdf
Data publikacji:: 2013
Wydawca:: Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:: conference
NADPH oxidase
arsenic
toxicity
oxidative metabolism
Arabidopsis thaliana
malondialdehyde
glutathione reductase activity
oxidative stress
reactive oxygen species
antioxidant
Źródło:: BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2013, 94, 2
0860-7796
Pojawia się w:: BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 10.

Tytuł:: Subcellular antioxidative defense of plants during abiotic stress
Autorzy:: Zechmann, B.
Powiązania:: https://bibliotekanauki.pl/articles/81187.pdf
Data publikacji:: 2013
Wydawca:: Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:: conference
antioxidant
ascorbate
glutathione
Arabidopsis thaliana
reactive oxygen species
redox signalling
gene expression
oxidative stress
abiotic stress
physiological condition
plant
Źródło:: BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2013, 94, 3
0860-7796
Pojawia się w:: BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 11.

Tytuł:: A comparison of antioxidant systems between Pisum sativum and Brassica juncea indicates high disproportion in H2O2 level
Autorzy:: Kutrowska, A.
Piechalak, A.
Wojtera-Kwiczor, J.
Malecka, A.
Tomaszewska, B.
Powiązania:: https://bibliotekanauki.pl/articles/80674.pdf
Data publikacji:: 2013
Wydawca:: Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:: conference
antioxidant
gene expression
Pisum sativum
Brassica juncea
hydrogen peroxide
trace element
reactive oxygen species
oxidative stress
Źródło:: BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2013, 94, 2
0860-7796
Pojawia się w:: BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 12.

Tytuł:: Activity of selected components of antioxidant system in grass pea and yellow lupine protoplasts after enzymatic isolation
Autorzy:: Wiszniewska, A.
Piwowarczyk, B.
Powiązania:: https://bibliotekanauki.pl/articles/80679.pdf
Data publikacji:: 2015
Wydawca:: Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:: antioxidant
phenolic compound
grass pea
Lathyrus sativus
yellow lupin
Lupinus luteus
peroxidase
radical scavenging activity
oxidative stress
Źródło:: BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2015, 96, 4
0860-7796
Pojawia się w:: BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 13.

Tytuł:: Antioxidant and DNA repair stimulating effect of extracts from Leonurus sibiricus against an induced oxidative stress and DNA damage in CHO cells
Autorzy:: Sitarek, P.
Skala, E.
Wysokinska, H.
Wielanek, M.
Szemraj, J.
Sliwinski, T.
Powiązania:: https://bibliotekanauki.pl/articles/951184.pdf
Data publikacji:: 2015
Wydawca:: Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:: conference
antioxidant
DNA repair
stimulating effect
Leonurus sibiricus
oxidative stress
DNA damage
secondary metabolite
polyphenolic acid
flavonoids
Chinese hamster ovary
Źródło:: BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2015, 96, 1
0860-7796
Pojawia się w:: BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 14.

Tytuł:: Antioxidants and environmental stress: spectroscopic study on stability of natural compounds and their interaction with a molecule of protein in an in vitro model
Antyoksydanty a stres środowiskowy, badania spektralne stabilności substancji naturalnych i ich oddziaływanie z molekułą białka
Autorzy:: Trnková, L.
Boušová, I.
Ryšánková, L.
Vrabcová, P.
Dršata, J.
Powiązania:: https://bibliotekanauki.pl/articles/126139.pdf
Data publikacji:: 2009
Wydawca:: Towarzystwo Chemii i Inżynierii Ekologicznej
Tematy:: oxidative stress
antioxidant
hydroxycinnamic acid
serum albumin
protein-ligand binding
stres oksydacyjny
antyoksydant
kwas hydrooksycynamonowy
albumina (BSA)
wiązanie białka z ligandem
Opis:: The stability of eight hydroxycinnamic acids (HCAs) during long-term incubation under physiological conditions was studied by UV-VIS absorption spectroscopy and their possibility of binding to a model protein (bovine serum albumin, BSA) under physiological conditions was investigated by tryptophan fluorescence quenching method. The obtained results suggest that the stability of hydroxycinnamic acids is dependent upon its individual structure and duration of incubation. The monosubstituted derivatives (coumaric acids) were stable within the course of long-term incubation, while di- and trisubstituted derivatives decomposed easily. It was found out that all studied compounds changed fluorescence emission spectrum of BSA. The Stern-Volmer analysis was employed in order to explore binding of HCAs to BSA in details. The binding constants (Kb), number of binding sites (n) and the free energy changes (∆G0) were determined. The binding affinity was strongest for rosmarinic acid and ranked in the following order rosmarinic acid > chlorogenic acid > sinapic acid > caffeic acid > ferulic acid > o-coumaric acid > p-coumaric acid > m-coumaric acid. All free energy changes (∆G0) possessed negative sign indicating the spontaneity of HCAs binding to BSA.
Badano trwałość ośmiu kwasów hydrooksycynamonowych, HCAs, podczas inkubacji długoterminowej w warunkach fizjologicznych i możliwość ich wiązania się z modelowym białkiem (albuminą, BSA). Uzyskane wyniki pokazały, że trwałość tych kwasów zależy od ich indywidualnej budowy oraz czasu inkubacji. Wyznaczono stałe trwałości (Kb), liczbę miejsc wiązania (n) oraz zmianę wartości energii Gibbsa (∆G0) wiązania HCAs do BSA, który to proces przebiegał samorzutnie.
Źródło:: Proceedings of ECOpole; 2009, 3, 1; 27-34
1898-617X
2084-4557
Pojawia się w:: Proceedings of ECOpole
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 15.

Tytuł:: Antioxidants and environmental stress: effect of low-molecular compounds on molecule of protein
Antyutleniacze i ich aktywność środowiskowa. Wpływ zwiążków drobnomolekularnych na proteinę
Autorzy:: Trnková, L.
Ortová, I.
Dršata, J.
Powiązania:: https://bibliotekanauki.pl/articles/127525.pdf
Data publikacji:: 2010
Wydawca:: Towarzystwo Chemii i Inżynierii Ekologicznej
Tematy:: environmental oxidative stress
antioxidant
tea catechin
serum albumin
protein-ligand binding
środowiskowy stres oksydacyjny
antyutleniacze
katechiny herbaty
albuminy surowicy
wiązanie białko-ligand
Opis:: The aim of this study was to evaluate the relationships between the chemical structure of tea catechins and their binding affinities to HSA (Human Serum Albumin) by fluorescence quenching method at pH 7.4 and 37°C. The quenching constants (Kq), binding constants (Kb), and free energy changes (∆G0) were determined for the tested systems. The presented study contributes to the current knowledge in the area of protein-ligand binding, particularly tea catechin-HSA interactions.
Celem pracy była ocena zależności między strukturą chemiczną katechin herbaty i ich powinowactwem do HSA (albumina ludzkiej surowicy) za pomocą metody wygaszania fluorescencji przy pH 7,4 i w temperaturze 37°C. Dla badanych układów wyznaczono stałą szybkości wygaszania (Kq), stałą wiązania (Kb) i zmiany entalpii swobodnej (∆G0). Prezentowana praca poszerza aktualny stan wiedzy na temat wiązania białko - ligand, zwłaszcza interakcji katechiny - HSA.
Źródło:: Proceedings of ECOpole; 2010, 4, 2; 291-296
1898-617X
2084-4557
Pojawia się w:: Proceedings of ECOpole
Dostawca treści:: Biblioteka Nauki

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