- Tytuł:
- Synthesis and biological activity of novel sulfonamides derivatives of various heterocyclic compounds
- Autorzy:
-
Meena, Lakshman R.
Sharma, Vinay S.
Swarnkar, Pawan - Powiązania:
- https://bibliotekanauki.pl/articles/1031472.pdf
- Data publikacji:
- 2020
- Wydawca:
- Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
- Tematy:
-
4-dichlorobenzoic acid
Sulfonamide
anti-fungal
anti-malarial
anti-microbial - Opis:
- A novel series of Sulfonamide embedded heterocyclic derivatives were synthesized and well characterized by using 1H NMR, 13C NMR and IR spectroscopic techniques. All the new synthesized compounds were evaluated to their anti-bacterial, anti-fungal and anti- malarial activities. Noticeably, compound 5b was the most potent compound in vitro anti-microbial (S. aureus) with a MTCC value of 96 microgram/ml and compounds 5g and 5j showed most potent activity in vitro anti-fungal (C. albicans) with a MTCC value of 277microgram/ml. Similarly, compound 5e showed high potent activity of anti-malarial (P. falciparum) with mean IC50 value as compared to other synthesized derivatives.
- Źródło:
-
World Scientific News; 2020, 142; 120-134
2392-2192 - Pojawia się w:
- World Scientific News
- Dostawca treści:
- Biblioteka Nauki
Artykuł