- Tytuł:
- A two-stage model of an arteriovenous fistula maturation process
- Autorzy:
-
Jodko, Daniel M.
Obidowski, Damian S.
Reorowicz, Piotr
Jóźwik, Krzysztof - Powiązania:
- https://bibliotekanauki.pl/articles/27324149.pdf
- Data publikacji:
- 2020
- Wydawca:
- Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
- Tematy:
-
hemodialysis
anastomosis
fluid structure interaction
wall shear stress
arteriovenous fistula AVF
AVF maturation
hemodializa
zespolenie
interakcja struktury płynu
naprężenie ścinające ściany
przetoka tętniczo-żylna AVF
dojrzewanie AVF - Opis:
- Purpose: An arteriovenous fistula has been a widely accepted vascular access for hemodialysis, however, a fistula maturation process is still not fully understood. In the short period of time, right after vein and artery shunting, the physical and biological changes take place mainly in the venous wall. A two-stage modeling method of arteriovenous fistula maturation process was proposed and presented. Methods: The first stage of the maturation was modeled with two-way coupled fluid structure interaction computer simulations. Whereas for the second, biological stage, a model was based on the change in the elasticity of the venous wall due to wall shear stress (WSS) modifications. Results: The relation between stress and radial and circumferential strain, based on Lame’s theory, makes possible to introduce a mathematical model defining modulus of elasticity, averaged WSS, and venous diameter as time functions. The presented model enables one to predict changes in the monitored parameters in the arteriovenous fistula taking place in the time longer than 90 days. Conclusions: We found that probably the majority of fistulas can be assessed to be mature too early, when the adequate blood flow rate is achieved but mean WSS still remains at the non-physiological level (>10 Pa).
- Źródło:
-
Acta of Bioengineering and Biomechanics; 2020, 22, 2; 139--153
1509-409X
2450-6303 - Pojawia się w:
- Acta of Bioengineering and Biomechanics
- Dostawca treści:
- Biblioteka Nauki
Artykuł