- Tytuł:
- New method for the study of Amaryllidaceae alkaloid biosynthesis using biotransformation of deuterium-labeled precursor in tissue cultures
- Autorzy:
-
El Tahchy, Anna
Boisbrun, Michel
Ptak, Agata
Dupire, François
Chrétien, Françoise
Henry, Max
Chapleur, Yves
Laurain-Mattar, Dominique - Powiązania:
- https://bibliotekanauki.pl/articles/1040425.pdf
- Data publikacji:
- 2010
- Wydawca:
- Polskie Towarzystwo Biochemiczne
- Tematy:
-
alkaloids
Leucojum aestivum
Amaryllidaceae
deuterated precursor
biotransformation - Opis:
- Biotransformation of deuterated-4'-O-methylnorbelladine into alkaloids galanthamine and lycorine in tissue cultures of Leucojum aestivum was demonstrated using HPLC coupled to mass spectrometry. GC-MS screening was also carried to investigate other native and deuterated alkaloids. A total of six labeled alkaloids were identified indicating that 4'-O-methyl-d3-norbelladine is incorporated into three different groups of Amaryllidaceae alkaloids that are biosynthesized by three modes of intramolecular oxidative phenol coupling.
- Źródło:
-
Acta Biochimica Polonica; 2010, 57, 1; 75-82
0001-527X - Pojawia się w:
- Acta Biochimica Polonica
- Dostawca treści:
- Biblioteka Nauki
Artykuł