- Tytuł:
- Effects of acetylsalicylic acid and a new pyrazine derivative PD-101 on sister chromatid exchange frequency and cell kinetics in cultured human lymphocytes
- Autorzy:
-
Wozniak, A
Limon, J.
Petrusewicz, J.
Kaliszan, R. - Powiązania:
- https://bibliotekanauki.pl/articles/2044238.pdf
- Data publikacji:
- 1998
- Wydawca:
- Polska Akademia Nauk. Czytelnia Czasopism PAN
- Tematy:
-
pyrazine
cell cycle
human lymphocyte
cytogenetic analysis
sister chromatid exchange
kinetics
chromosome aberration
in vitro
acetylsalicylic acid - Opis:
- Acetylsalicylic acid (ASA) and α-2-pyrazylidene-α-cyano N-butyl acetamide (PD-101), a new antiaggregatory pyrazine derivative were tested for their genotoxicity in human lymphocytes in vitro using the sister chromatid exchange (SCE) technique. Both compounds were found to be inactive in inducing SCE in concentration from 1 µM up to 1000 µM. The agents displayed inhibitory effect on cell kinetics.
- Źródło:
-
Journal of Applied Genetics; 1998, 39, 3; 281-287
1234-1983 - Pojawia się w:
- Journal of Applied Genetics
- Dostawca treści:
- Biblioteka Nauki
Artykuł