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Wyświetlanie 1-3 z 3
Tytuł:
Physical activity in type 2 diabetes mellitus: a review
Autorzy:
Burooj, Ahmed
Powiązania:
https://bibliotekanauki.pl/articles/33777868.pdf
Data publikacji:
2024-04-10
Wydawca:
Gdański Uniwersytet Medyczny
Tematy:
T2DM
Exercise
Diabetes
Diabetes Mellitus
Physical Activity
Opis:
Introduction This literature review explores the role of physical activity (PA) in managing and preventing type 2 diabetes mellitus (T2DM), synthesizing the latest guidelines for all T2DM patients. Following PRISMA guidelines, it identifies specific areas for further research. Material and Methods Indexing services (PubMed and Scopus) were used to identify relevant studies, emphasizing original research, review articles, and updated institutional guidelines spanning 2017-2023. The following keywords were used: diabetes, physical activity, type 2 diabetes mellitus, PA, and exercise. Proposal and opinion articles, non-English papers (or those lacking full-text translation), studies involving non-human subjects, pediatric populations or with skewed gender distribution were excluded. Results PA improves quality of life, BMI, glycemic control and well-being. Effects vary by activity domain, such as work or leisure time. Recommendations suggest 60 daily minutes of exercise for children, 150 weekly minutes of moderate intensity exercise for adults, and screening for adverse events. A “sit-less” approach is proposed for those unable to maintain regular activity, with glycemic monitoring for those with variability. Conclusions PA is crucial in T2DM management. Conflicting findings regarding glycemic control warrant further investigation to ascertain causes, whether related to bias or other factors.
Źródło:
European Journal of Translational and Clinical Medicine; 2024, 7, 1; 97-105
2657-3148
2657-3156
Pojawia się w:
European Journal of Translational and Clinical Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Lack of association between UBE2E2 gene polymorphism (rs7612463) and type 2 diabetes mellitus in a Saudi population
Autorzy:
Alharbi, Khalid
Khan, Imran
Al-Sheikh, Yazeed
Alharbi, Fawiziah
Alharbi, Fahad
Al-Nbaheen, May
Powiązania:
https://bibliotekanauki.pl/articles/1039212.pdf
Data publikacji:
2014
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
T2DM
UBE2E2
PCR-RFLP
Saudi population
Opis:
The ubiquitin-conjugating enzyme E2E 2 (UBE2E2) gene plays an important role in insulin synthesis and secretion under conditions in which stress to the endoplasmic reticulum is increased in β-cells. In this case-control study, we have selected rs7612462 polymorphism within UBE2E2 gene to identify in a Saudi population the type 2 diabetes mellitus (T2DM) subjects. In total, 376 subjects with T2DM and 380 controls were enrolled in this study. We have collected 5 mL of peripheral blood from each participant for biochemical and molecular analyses. PCR-RFLP was used to generate genotypes at rs7612462 in all of the study subjects. Clinical data and anthropometric measurements of the patients were significantly different from those of the controls (p<0.05). All of the subjects used in this study were non-obese (25
Źródło:
Acta Biochimica Polonica; 2014, 61, 4; 769-772
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Association of fat patterning, type 2 diabetes mellitus and MTHFR gene polymorphism: a study among the two ethnic groups of Tripura, North-East India
Autorzy:
Bhattacharya, Priyama
Chatterjee, Diptendu
Sarkar, Pranabesh
Ghosh, Kusum
Bandyopadhyay, Arup Ratan
Powiązania:
https://bibliotekanauki.pl/articles/454801.pdf
Data publikacji:
2019
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
fat patterning
MTHFR
obesity
T2DM
Opis:
Introduction. Type 2 Diabetes Mellitus (T2DM) is a group of metabolic disorders resulting from insufficient action of insulin. The etiology of T2DM is multi-factorial that includes genetic factors, obesity and lifestyles. Recent reviews of overall and stratified meta-analyses demonstrated the association between MTHFR polymorphism (C677T) including fat distribution and risk of T2DM. Publications of Indian context regarding fat patterning and MTFHR genetic polymorphism of the North East Indian population are insufficient and scant among the ethnic population of Tripura. Aim. In this backdrop, the present study is the first attempt to understand the relationship of fat patterning, MTHFR gene polymorphism and T2DM among two Tibeto-Burman speaker endogamous ethnic populations (Chakmas-the migrant group and Tripuris – the aboriginal group) of Tripura, North East India. Material and methods. The present study consists of age matched 280 males (Chakmas 147 and the Tripuris 133) from Tripura. Anthropometric and metabolic (Fasting Blood Glucose) variables and to discern obesity, blood glucose level and genotyping of MTHFR was performed following standard techniques. Results. The result revealed significant (p<0.05) association of obesity, TT genotypes and fasting blood glucose among the Chakmas with in comparison to the Tripuris. Conclusion. In this first attempt from North East India on the aspects of association of fat Patterning, Type 2 Diabetes Mellitus and MTHFR gene polymorphism suggests that the Chakmas are more diabetic, and this might be due to the concomitant effects of T alleles and higher central obesity and Percent Body Fat (PBF). More population screening from other under-represented indigenous populations of North East India is needed for prevention of metabolic disorders.
Źródło:
European Journal of Clinical and Experimental Medicine; 2019, 3; 209 - 213
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-3 z 3

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