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    Tytuł:
    Impact of Rectal Artesunate on Haematological Parameters of Children of Ogun State, South-Western Nigeria
    Autorzy:
    Agbeyangi, O. A.
    Sam-Wobo, S. O.
    Ekpo, U. F.
    Akinloye, O. A.
    Mafiana, C. F.
    Powiązania:
    https://bibliotekanauki.pl/articles/1179588.pdf
    Data publikacji:
    2017
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    Anaemia
    Children
    Effectiveness
    Malaria
    Ogun State
    Rectal Artesunates
    South-western Nigeria
    Opis:
    Impact of Rectal Artesunate on haematological parameters was assessed in 905 children below the age of 5 years. Grid systematic method was employed in selecting sixteen study centres from 8 Local Government Areas of Ogun State. Ethical approvals were obtained in addition to interactive sessions with parents of the children and PHCs medical practitioners. Drug was administered at a dose of 5 to 10mg/kg of the body weight per rectum at 0 hour, 24 hours and 48 hours. Data obtained were analyzed using SPSS version 20 to assess association with p-value of < 0.05. Impact of Rectal Artesunate was monitored by analysing blood samples taken at 0 hour, 24 hours and 48 hours for Packed Cells Volume (PCV) and Haemoglobin concentration (Hb). There was a significant (p < 0.05) increase in baseline PCV (L/L) and Hb (g/L) during 48 hours across the LGAs. Parasitaemia (MPC/µl) in children has a significant (p < 0.05) association with anaemia (PCV and Hb) and was positively correlated (r = +0.348 and r =+ 0.201). A significant (p < 0.05) difference observed between MCV (fl), MCH (pg) and MCHC (g/L) at 0 hour and MCV (fl), MCH (pg) and MCHC (g/L) at 48 hours. More awareness on the use of Rectal Artesunate in reducing anaemia due to malaria in children should be created since it is highly effective antimalarial suppository.
    Źródło:
    World Scientific News; 2017, 74; 80-93
    2392-2192
    Pojawia się w:
    World Scientific News
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Community Based Management, Environmental Factors and Ecological Patterns Associated with Malaria Parasites Transmission in the Communities of Children Treated with Rectal Artesunate in Ogun State, South-Western Nigeria
    Autorzy:
    Agbeyangi, O. A.
    Sam-Wobo, S. O.
    Ekpo, U. F.
    Akinloye, O. A.
    Mogaji, H. O.
    Oluwole, A. S.
    Bello, A. A.
    Powiązania:
    https://bibliotekanauki.pl/articles/1178283.pdf
    Data publikacji:
    2017
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    Community-based management
    Ogun State
    South-western Nigeria
    malaria
    mosquitoes vegetation topographic environmental management
    Opis:
    Community-based case management of malaria has been shown to be effective in reducing mortality and morbidity. Overall total of 183 communities comprising 36(19.7%) communities in Egba Goe-Political Zone (GPZ), 56(30.6%) in Yewa-Awori GPZ, 43(23.5%) in Remo GPZ, and 48(26.2%) in Ijebu GPZ. There was a significant (p = 0.011) difference between preventive measures against malaria adopted for children across LGAs. Involvement in environmental management /sanitation as part of control measure (78.0%) can mostly help in tackling the adverse effects of malaria parasites transmission. They also agreed that mosquitoes breed majorly in stagnant water (77%) and Ponds (74.6%) and they did not always use (54.4%) their ITN/LLITN and their family mostly used ITN/LLITN during rainy season (84.4%). Fresh-water Rain Forest (44.3%) and Lowland Rain Forest (43.2%) are common forest vegetation types. Communities having plains topographical structure were more (91.3%) with close/compact (54.6%) type of settlement and are more densely populated (51.9%). Water bodies present are small rivers (100%). House type common in the communities was mud with iron sheets (100%) and drainage system (36.2%) was not common. Communities Involvement in environmental management/sanitation as part of control measure will reduce malaria parasite transmission.
    Źródło:
    World Scientific News; 2017, 86, 3; 150-167
    2392-2192
    Pojawia się w:
    World Scientific News
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Knowledge Attitude and Practices of Caregivers on Management and Treatment of Childhood Malaria in Ogun State, South-Western Nigeria
    Autorzy:
    Agbeyangi, O. A.
    Sam-Wobo, S. O.
    Ekpo, U. F.
    Akinloye, O. A.
    Mafiana, C. F.
    Ajayi, J. B.
    Powiązania:
    https://bibliotekanauki.pl/articles/1179169.pdf
    Data publikacji:
    2017
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    Ogun State
    South-western Nigeria
    home management of malaria
    treatment seeking behaviours
    Opis:
    Home management of malaria involves presumptively treating febrile children at clinic or near home with antimalarial drugs distributed by trained members of the community provide medications and educate primary caregivers about treatment of malaria and recognition of severe illness. Structured questionnaires were administered to the parents, health workers and patent medicine vendors to determine acceptability of rectal artesunate and treatment seeking behaviours. Data obtained were analyzed using SPSS version 20 to assess association with p-value of < 0.05. Current first line antimalarial drug for treating childhood malaria at the PHCs was artesunate derivatives (90.3%) with no usage of chloroquine derivatives (0%) and common route of administration was intra-muscular (81.4%) with least usage of rectal (6.2%). Patent medicine vendors showed that the common drug derivatives purchase for treating childhood malaria was chloroquine derivatives (89.2%) with oral (91.9%) as most common route of administration and no awareness of rectal route (0%). Cases of resistance of malaria parasites to anti-malarial drugs, mostly chloroquine derivatives (89.3%) and least with artesunate derivatives (7.1%) observed by health workers. Incomplete dosage (95.6%) and fake drug (84.9%) were described as main factors responsible for malaria parasite resistance. Patent medicine vendors have come across cases of resistance of malaria parasites to anti-malarial drugs mostly chloroquine derivatives (93.2%) with drug abuse (89.2%) and fake drug (82.4%). Treatment of malaria is challenged by inadequate health-care infrastructure and community-based interventions.
    Źródło:
    World Scientific News; 2017, 83; 62-74
    2392-2192
    Pojawia się w:
    World Scientific News
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-3 z 3

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