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Wyświetlanie 1-4 z 4
Tytuł:
Healthcare workers highly affected during the COVID-19 epidemic wave in Poland prior to vaccination availability: seroprevalence study
Autorzy:
Rosińska, Magdalena
Stępień, Małgorzata
Kitowska, Wioleta
Milczarek, Małgorzata
Juszczyk, Grzegorz
Nowacka, Zuzanna
Gardel, Aneta
Hermann, Adam
Bardoń-Błaszkowska, Aneta
Cudnik, Rafał
Czubak, Hanna
Wolniak-Bińkowska, Magdalena
Źródłowska, Izabella A.
Sadkowska-Todys, Małgorzata
Powiązania:
https://bibliotekanauki.pl/articles/2081141.pdf
Data publikacji:
2022-04-22
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
Polska
risk factors
COVID-19
SARS-CoV-2
healthcare workers
seroprevalence
Opis:
The aim of the study was to assess seroprevalence of anti-SARS-CoV-2 antibodies among healthcare workers (HCW) before introduction of vaccination, in selected areas in Poland as well as to identify potential risk factors and estimate the cumulative incidence of COVID-19 infections in this population.Material and MethodsThe authors conducted a sero-epidemiological, cross-sectional study among HCW of 5 non-COVID-19 hospitals in Poland. The recruitment took place in December 1–23, 2020, all HCW at selected hospitals could volunteer into the study. All persons were screened with rapid SARS-CoV-2 IgM/IgG tests in capillary blood. In case of positive result, 5 ml of venous blood was drawn for confirmatory testing with ELISA assay. The authors estimated prevalence of laboratory confirmed anti-SARS-CoV-2 antibody presence and examined factors associated with positive result. Cumulative incidence was estimated applying 2-source capture-recapture method to serology results and self-report of past infection.ResultsOut of 1040 HCW included in the analysis, one-fourth (25.2%) received a positive result for anti-SARS-CoV-2 antibodies by ELISA test, the prevalence among women was 25.3% (95% CI: 22.5–28.4) and 24.6% (95% CI: 19–31.2) among men. The prevalence of anti-SARS-CoV-2 antibodies was the highest among respondents who declared home contact with a confirmed COVID-19 case, 43.9% (95% CI: 32.4–56.1). It was also elevated among those who indicated contact with patients with COVID-19, 32.5% (95% CI: 26.7–38.8) and business contacts, including at the workplace, 28.9% (95% CI: 22.5–36.3). The estimated cumulative incidence of COVID-19 infections in the population, using the capture-recapture method was 41.2% (95% CI: 38.1–44.2).ConclusionsHealthcare workers remained at increased risk of infection largely due to work-related contacts with infected patients, although home exposure was also common. Estimated cumulative incidence is higher than the antibody prevalence, which indicates the need to monitor HCW for possible immunity waning, also post-immunization immunity. Med Pr. 2022;73(2):109–23
Źródło:
Medycyna Pracy; 2022, 73, 2; 109-123
0465-5893
2353-1339
Pojawia się w:
Medycyna Pracy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Clinical and epidemiological characteristics of COVID-19 during the early phase of the SARS-CoV-2 pandemic: a cross-sectional study among medical school physicians and residents employed in a regional reference teaching hospital in Northern Italy
Autorzy:
Dini, Guglielmo
Montecucco, Alfredo
Rahmani, Alborz
Barletta, Chiara
Pellegrini, Luca
Debarbieri, Nicoletta
Orsi, Andrea
Caligiuri, Patrizia
Varesano, Serena
Manca, Alessia
Vargiu, Maria Paola
Di Carlo, Pia
Massa, Emanuela
Icardi, Giancarlo
Durando, Paolo
Powiązania:
https://bibliotekanauki.pl/articles/2086076.pdf
Data publikacji:
2021-05-27
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
occupational health
epidemiology
healthcare workers
clinical characteristics
COVID‑19
SARS-CoV-2
Opis:
ObjectivesThe aim of the study was to evaluate the clinical presentation and burden of SARS-CoV-2 infections among medical school physicians and residents, mainly young medical doctors. The awareness of COVID‑19 clinical manifestations can improve the early detection of mild cases, possibly reducing further transmission to colleagues and patients.Material and MethodsThe study was carried out in March–May 2020, involving medical school physicians in a teaching hospital in northern Italy, with a working population of 881 medical doctors. Data collection was performed using a structured form investigating clinical and epidemiological information.ResultsOne hundred sixty-two medical doctors contacted the Occupational Health Service reporting acute respiratory symptoms or close contact exposure to a confirmed COVID‑19 case. Among the confirmed COVID‑19 cases, most were male doctors during residency, and 85% presented a mild clinical picture. Fever (70.3%) and cough (51.4%) represented the most prevalent symptoms of COVID‑19. As revealed by the univariate analysis, the prevalence of real-time reverse transcriptase-polymerase chain reaction (RT-PCR) positivity increased with age (OR = 1.08, 95% CI: 1.02–1.14, p = 0.012), working in a COVID‑19 ward (OR = 3.33, 95% CI: 1.09–10.21, p = 0.031), presenting alteration or loss of smell/taste (OR = 10.00, 95%CI: 2.80–35.69, p < 0.001) and myalgia (OR = 3.20, 95% CI: 1.00–10.26, p = 0.046), while being a resident (OR = 0.20, 95% CI: 0.05–0.80, p = 0.030) was associated with reduced odds of being infected, compared to staff physicians. Age and loss of smell/taste were the only factors independently associated with RT-PCR positivity.ConclusionsThe majority of COVID‑19 cases showed a mild clinical syndrome, ranging from absence or paucity of symptoms to common cold or influenza-like symptoms. The findings of the present study increase the accuracy of the clinical diagnosis for the prompt identification and management of suspected COVID‑19 cases, being particularly useful during resurges of the SARS-CoV-2 pandemic.
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2021, 34, 2; 189-201
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Acute SARS-CoV-2 infection and seropositivity among healthcare workers and medical students in summer 2020, Hungary
Autorzy:
Kosztin, Annamária
Merkely, Béla
Szabó, Attila J.
Blaha, Béla
Varga, Péter
Vásárhelyi, Barna
Vokó, Zoltán
Powiązania:
https://bibliotekanauki.pl/articles/2084806.pdf
Data publikacji:
2022-04-11
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
polymerase chain reaction
medical students
seropositivity
COVID-19
SARS-CoV-2
healthcare workers
Opis:
ObjectivesThe aim was to compare the prevalence of acute infection and seropositivity of SARS-CoV-2 among healthcare workers (HCWs) and medical students.Material and MethodsA high-volume, single-center analysis was conducted in the period of July 1‒August 1, 2020, at the Semmelweis University. Naso- and oropharyngeal samples were collected for polymerase chain reaction (PCR), and blood samples for anti-SARS-CoV-2 IgG. A questionnaire was also administered about the infection symptoms and the obtained results were assessed by profession and site of care delivery.ResultsFrom the total cohort (N = 7948), 4478 (56%) and 3470 (44%) were health professionals and medical students, respectively. They were mainly female (67%), and the mean age of HCWs and students was 40 and 25 years, respectively. By profession, physicians (1.5%) and other HCWs (1.8%) showed a comparable SARS-CoV-2 exposure. International students had the highest (2.1%), whereas Hungarian students had the lowest (0.6%) prevalence of seropositivity. The highest prevalence was detected among the staff of COVID-19 wards (12.1%). By PCR, medical students showed the lowest occurrence of active infection with a prevalence of 0.17%, while physicians and other HCWs had a higher prevalence (1.46% and 1.71%, respectively). By site of care delivery, positive test results were the most frequent at COVID-19 wards (3.8%).ConclusionsPhysicians and other HCWs showed comparable SARS-CoV-2 seropositivity prevalence, approximately twice as high as in the general population of Budapest. Hungarian students had lower prevalence of seropositivity than this reference. High prevalence among international students suggests that they had imported the infection. The very high prevalence of documented exposure among staff members at COVID-19 wards urges for improving the safety measures.
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2022, 35, 2; 209-216
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Częstość pozytywnych wyników testów serologicznych przeciw SARS-CoV-2 u personelu medycznego Aglomeracji Górnośląskiej
The frequency of positive results of serological tests against SARS-CoV-2 in healthcare workers in Upper Silesia Metropolitan Area, Poland
Autorzy:
Wojczyk, Marek
Kowalska, Małgorzata
Powiązania:
https://bibliotekanauki.pl/articles/2081163.pdf
Data publikacji:
2022-04-22
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
epidemia
personel medyczny
zakażenie
SARS-CoV-2
COVID-19
przeciwciała IgG
epidemy
healthcare workers
infection
IgG antibodies
Opis:
Śląsk jest jednym z regionów Polski najbardziej dotkniętych przez epidemię COVID-19. Wysoka liczba zakażeń wśród mieszkańców zwiększa i tak wysokie ryzyko zakażenia SARS-CoV-2 pracowników medycznych, którzy ze względu na swoją pracę są narażeni na kontakt z nosicielami SARS-CoV-2 częściej niż osoby z populacji ogólnej. Celem niniejszego badania była ocena na podstawie wyników badania seroepidemiologicznego rozpowszechnienia zakażenia SARS-CoV-2 wśród pracowników ochrony zdrowia z Aglomeracji Górnośląskiej.Materiał i metodyBadanie seroepidemiologiczne przeprowadzono w okresie październik–listopad 2020 r. wśród mieszkańców Aglomeracji Górnośląskiej (objęło m.in. osoby wykonujące zawody medyczne, które wyselekcjonowano, tworząc grupę badanych pracowników medycznych). Poza przeprowadzeniem badania kwestionariuszowego, niezbędnego do ustalenia objawów, okoliczności oraz czynników ryzyka sprzyjających zakażeniu, oceniono obecność swoistych przeciwciał przeciwko SARS-CoV-2 w klasach IgG oraz IgM.WynikiW badaniu wzięło udział 575 osób deklarujących wykonywanie zawodu medycznego. Dodatni wynik testu na obecność przeciwciał w klasie IgG uzyskano u 19,1% badanych, a w klasie IgM – u 4,3% badanych. Dodatnie wyniki, wskazujące na zakażenie SARS-CoV-2, najczęściej dotyczyły osób deklarujących wcześniejszy kontakt z osobą zakażoną (p = 0,001) oraz odbywających kwarantannę (p < 0,0001).WnioskiCzęstość zakażeń SARS-CoV-2 u personelu medycznego w Aglomeracji Górnośląskiej, oceniana na podstawie pozytywnego wyniku testu przeciwciał w klasie IgG, wynosi 16,1–22,5%. Med. Pr. 2022;73(2):125–133
Silesia is one of the regions in Poland most affected by the COVID-19 epidemic. The high number of infections among the inhabitants of the region increases the already high risk of infection of SARS-CoV-2 virus of medical workers who, due to their work, are more likely to be exposed to people with SARS-CoV-2 than people from the general population. The aim of this study is to assess the prevalence of SARS-CoV-2 infection among healthcare workers in the Upper Silesia Metropolitan Area based on the results of a seroepidemiological study.Material and MethodsThe seroepidemiological study was carried out in October– November 2020 among the inhabitants of the Upper Silesia Metropolitan Area (including medical professionals who were selected, creating a research group of healthcare workers). Apart from the questionnaire examination necessary to determine the declared symptoms, circumstances and risk factors conducive to infection, the level of specific antibodies against the SARS-CoV-2 virus in the IgG and IgM class was assessed.ResultsIn the study participated 575 people declaring their medical profession. A positive test for the presence of IgG antibodies was confirmed in 19.1% of the respondents, while a positive test for IgM concerned 4.3% of the subjects. The most common positive results indicating infection with the SARS-CoV-2 virus concerned people declaring prior contact with an infected person (p = 0.001) and those undergoing quarantine (p < 0.0001).ConclusionsThe frequency of SARS-CoV-2 virus infections in medical personnel in the Upper Silesia Metropolitan Area, assessed on the basis of a positive IgG antibody test result, was 16.1–22.5%. Med Pr. 2022;73(2):125–33
Źródło:
Medycyna Pracy; 2022, 73, 2; 125-133
0465-5893
2353-1339
Pojawia się w:
Medycyna Pracy
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-4 z 4

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