- Tytuł:
- Role of the host genetic variability in the influenza A virus susceptibility
- Autorzy:
-
Arcanjo, Ana
Mazzocco, Giovanni
de Oliveira, Silviene
Plewczynski, Dariusz
Radomski, Jan - Powiązania:
- https://bibliotekanauki.pl/articles/1039238.pdf
- Data publikacji:
- 2014
- Wydawca:
- Polskie Towarzystwo Biochemiczne
- Tematy:
-
Influenza A virus
host-pathogen interactions - Opis:
- The aftermath of influenza infection is determined by a complex set of host-pathogen interactions, where genomic variability on both viral and host sides influences the final outcome. Although there exists large body of literature describing influenza virus variability, only a very small fraction covers the issue of host variance. The goal of this review is to explore the variability of host genes responsible for host-pathogen interactions, paying particular attention to genes responsible for the presence of sialylated glycans in the host endothelial membrane, mucus, genes used by viral immune escape mechanisms, and genes particularly expressed after vaccination, since they are more likely to have a direct influence on the infection outcome.
- Źródło:
-
Acta Biochimica Polonica; 2014, 61, 3; 403-419
0001-527X - Pojawia się w:
- Acta Biochimica Polonica
- Dostawca treści:
- Biblioteka Nauki
Artykuł