- Tytuł:
- Synthesis, Characterization and Anti-diabetic activity of 1,3,5-triaryl-2-pyrazolines in acetic acid solution under Ultrasound Irradiation
- Autorzy:
-
Emayavaramban, M.
Santhi, N.
Gopi, C.
Manivannan, C.
Raguraman, A. - Powiązania:
- https://bibliotekanauki.pl/articles/412176.pdf
- Data publikacji:
- 2013
- Wydawca:
- Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
- Tematy:
-
Chalcone
Pyrazoline
ultrasound irradiation
Anti-diabtic activity and Alloxan Monohydrate - Opis:
- A chalcone was prepared by the reaction of 4-methylbenzaldehyde with 4-methylacetophenone in dilute methanolic sodium hydroxide solution under ultrasonic irradiationin the water bath of an ultrasonic cleaner at room temperature. Treatment of this chalcone with thiosemicarbazide / semicarbazide hydrochloride / benzhydrazide / benzenesulphonyl hydrazide / phenylhydrazine hydrochloride afforded the corresponding 2-pyrazoline in good yields. All the new compounds have been characterized by IR, 1H-NMR, 13CNMR spectral data. All the target compounds were evaluated for their in-vivo anti - diabetic activity in rates in comparison with as reference drug.
- Źródło:
-
International Letters of Chemistry, Physics and Astronomy; 2013, 9, 2; 172-185
2299-3843 - Pojawia się w:
- International Letters of Chemistry, Physics and Astronomy
- Dostawca treści:
- Biblioteka Nauki
Artykuł