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Wyświetlanie 1-2 z 2
Tytuł:
Assessment of Candida spp. frequency in the oral cavity ontocenosis of healthy individuals in different age groups
Autorzy:
Szymańska, Jolanta
Wójtowicz, Agnieszka
Malm, Anna
Powiązania:
https://bibliotekanauki.pl/articles/972336.pdf
Data publikacji:
2016
Wydawca:
Instytut Medycyny Wsi
Tematy:
fungi
Candida spp
Candida albicans
Opis:
Introduction. Among the microorganisms colonizing the oral cavity ontocenosis, an important role is played by fungi: mainly yeast-like fungi of the Candida genus, and especially by the species C. albicans. Objective. The aim of this study was to evaluate the frequency of oral colonization by Candida species in healthy individuals of different age groups, and to identify the species of the isolates. Materials and method. The fungi were isolated from the oral cavities of 654 healthy individuals of both genders, representing different age groups, and the species of the isolates were determined. Initial identification of the yeast-like fungi was made based on the macroscopic appearance of the colonies on Sabouraud’s medium, and the growth of coloured colonies on ChromAgar Candida medium. API 20 C AUX microtest (bioMerieux) was used to identify the most frequently found species of Candida spp. Results. The frequency of Candida isolation from the oral cavity ontocenosis in healthy individuals of different age groups was assessed as 30.6%. The oral cavity ontocenosis was colonized mainly by the yeast-like fungi of C. albicans species: they were found in 24.5% of the tested population, while the frequency of oral cavity colonization by non-albicans Candida spp. was 6.1%. Seven species of non-albicans Candida spp. were identified: C. glabrata, C. inconspicua, C. famata, C. tropicalis, C. parapsilosis, C. lusitaniae, and C. kefyr. Conclusions. In the Polish population, 30.6% of the oral cavity ontocenosis is colonized by Candida yeast-like fungi, while C. albicans is the fungus that colonizes oral cavity ontocenosis most frequently. The frequency of oral cavity ontocenosis colonization with Candida spp (including C. albicans) increases with age.
Źródło:
Journal of Pre-Clinical and Clinical Research; 2016, 10, 2; 91-94
1898-2395
Pojawia się w:
Journal of Pre-Clinical and Clinical Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
In vitro susceptibility of oral Candida albicans isolates to chlorhexidine
Autorzy:
Biernasiuk, Anna
Szymańska, Jolanta
Kustra, Agata
Korona-Głowniak, Izabela
Malm, Anna
Powiązania:
https://bibliotekanauki.pl/articles/895468.pdf
Data publikacji:
2018-06-30
Wydawca:
Polskie Towarzystwo Farmaceutyczne
Tematy:
antifungal agents
Candida albicans
chlorhexidine
Opis:
Fungal infections are an important medical problem in patients from different risk groups. The majority of these infections are caused by Candida spp., with over 50 % due to C. albicans. The purpose of the study was to evaluate in vitro chlorhexidine effect on C. albicans colonizing the mouth and throat isolated from 5 population groups. The study material included the reference strains of C. albicans ATCC 2091 and C. albicans ATCC 10231, routinely used for evaluation of antimicrobials, and 120 clinical isolates of C. albicans from: hospitalized cancer patients (30 isolates), chronic HCV patients (31 isolates), immunocompromised patients (28 isolates), healthy school-age children (31 isolates), elderly people – aged 65 years or older (30 isolates). Chlorhexidine inhibited the growth of C. albicans at the concentrations of 0.625-5 µg/ml (in particular, 2.5 µg/ml solution was effective against strains from immunocompromised patients and 5 µg/ml – against the remaining isolates). The yeasts were also killed by 2.5-20 µg/ml chlorhexidine solutions. The concentration of 5 µg/ml was particularly active against the strains isolated from the elderly, immunocompromised and lung cancer patients, while 10 µg/ml inhibited the growth of the strains from the remaining two groups. Moreover, C. albicans isolates from hepatitis C patients and healthy children comparing to strains from the elderly were less sensitive to chlorhexidine fungicidal effect and these differences were statistically significant. According to our studies, the fungicidal effect of chlorhexidine seems to depend on the origin of the tested oral C. albicans strains from various patient groups.
Źródło:
Acta Poloniae Pharmaceutica - Drug Research; 2018, 75, 3
0001-6837
2353-5288
Pojawia się w:
Acta Poloniae Pharmaceutica - Drug Research
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-2 z 2

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