- Tytuł:
- NOD1 and NOD2 receptors: integral members of the innate and adaptive immunity system
- Autorzy:
-
Antosz, Halina
Osiak, Magdalena - Powiązania:
- https://bibliotekanauki.pl/articles/1039530.pdf
- Data publikacji:
- 2013
- Wydawca:
- Polskie Towarzystwo Biochemiczne
- Tematy:
-
NOD1
NOD2
CARD
NF-κB - Opis:
- NOD-like proteins (NLR) are a specialized group of intracellular receptors, which constitute an essential component of the host innate immune system. They were discovered more than a decade ago, but research on this particular class of microbial detectors is still ongoing to allow for a better understanding of the mechanisms, recognition of microorganisms, transmission of signals, and carrying out the activation of inflammatory signaling pathways. In this review, we discuss the construction of NOD1 and NOD2 receptors, their functions, and significance in the pathogenesis of inflammatory diseases in humans.
- Źródło:
-
Acta Biochimica Polonica; 2013, 60, 3; 351-360
0001-527X - Pojawia się w:
- Acta Biochimica Polonica
- Dostawca treści:
- Biblioteka Nauki
Artykuł