- Tytuł:
- Synthesis, spectral studies and antimicrobial activities of some substituted (E)-1-benzylidene-2-(4-bromophenyl)hydrazines
- Autorzy:
-
Rajarajan, M.
Senbagam, R.
Vijayakumar, R.
Manikandan, V.
Balaji, S.
Vanangamudi, G.
Thirunarayanan, G. - Powiązania:
- https://bibliotekanauki.pl/articles/1194024.pdf
- Data publikacji:
- 2015
- Wydawca:
- Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
- Tematy:
-
Antimicrobial study
Hammett equation
Hydrazone
IR spectra
NMR spectra
Synthesis
UV - Opis:
- A series of nine number of (E)-1-benzylidene-2-(4-bromophenyl)hydrazine compounds have been synthesized by the condensation reaction of 4-bromo phenylhydrazine with varies m- and p- substituted benzaldehydes using acetic acid catalyst were refluxed for 4h with 20 mL of absolute ethanol. The yield of synthesized (E)-1-benzylidene-2-(4-bromophenyl)hydrazine compounds are more than 80%. The synthesized (E)-1-benzylidene-2-(4-bromophenyl)hydrazines have been characterized by UV, IR, 1H and 13C spectral data. These UV, IR and NMR spectral data have been correlated with varies Hammett substituted constant and Swain-Lupton F and R parameters using single and multi- regression analysis. From the results of statistical analysis, the effects of substituent have been studied. The antimicrobial activity of all the synthesized substituted (E)-1-benzylidene-2-(4-bromophenyl)hydrazines have been evaluated using Bayer-Kirby method.
- Źródło:
-
World Scientific News; 2015, 9; 144-160
2392-2192 - Pojawia się w:
- World Scientific News
- Dostawca treści:
- Biblioteka Nauki
Artykuł