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    Wyświetlanie 1-6 z 6
    Tytuł:
    Synthesis, spectral correlation analysis and evaluation of biological activities of some substituted hydrazones
    Autorzy:
    Vijayakumar, Renganathan
    Senbagam, Rajamohan
    Rajarajan, Murugan
    Balaji, Selvaraj
    Manikandan, Venkatesan
    Vanangamudi, Ganesan
    Thirunarayanan, Ganesamoorthy
    Powiązania:
    https://bibliotekanauki.pl/articles/764124.pdf
    Data publikacji:
    2015
    Wydawca:
    Uniwersytet Marii Curie-Skłodowskiej. Wydawnictwo Uniwersytetu Marii Curie-Skłodowskiej
    Tematy:
    Hydrazones
    UV
    IR & NMR spectra
    Correlation analysis
    Antimicrobial activities
    Opis:
    Some novel substituted hydrazone derivatives of amino guanidine have been synthesized with different substituted benzaldehydes by condensation method. The synthesized hydrazones were characterized by their physical constants, UV, IR and NMR spectra. The spectral data have been correlated with Hammett substituent constants and Swain–Lupton parameters. From the result of statistical analysis, the effects of substituents on the spectral data have been predicted. The antimicrobial activities of these synthesized hydrazone compounds have been screened by Bauer-Kirby method using human pathogenic bacteria and fungal species. The antimicrobial activities of all synthesized hydrazone compounds have shown significant activity.
    Źródło:
    Annales Universitatis Mariae Curie-Skłodowska, sectio AA – Chemia; 2015, 70, 2
    2083-358X
    Pojawia się w:
    Annales Universitatis Mariae Curie-Skłodowska, sectio AA – Chemia
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Cu2+/Zeolite catalyzed synthesis and evaluation of antimicrobial activities of some chalcones
    Autorzy:
    Thirunarayanan, G.
    Kumar, N. Dinesh
    Powiązania:
    https://bibliotekanauki.pl/articles/1179609.pdf
    Data publikacji:
    2017
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    Antimicrobial activities
    Aryl chalcones
    Cu2+/Zeolite
    IR and NMR spectra
    Opis:
    Some aryl chalcones have been synthesized by Cu2+/Zeolite catalyzed aldol condensation of aryl methyl ketones and substituted benzaldehydes under microwave irradiation conditions. The yields of the synthesized chalcones are more than 85%. These chalcones were characterized by their physical constants and spectroscopic data. The antimicrobial activities of synthesized chalcones were studied by Bauer-Kirby disc diffusion method.
    Źródło:
    World Scientific News; 2017, 74; 251-266
    2392-2192
    Pojawia się w:
    World Scientific News
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Synthesis, assessment of substituent effect and antimicrobial activities of some substituted (E)-Nbenzylidene- 5-bromopyridin-2-amines
    Autorzy:
    Senbagam, Rajamohan
    Vanangamudi, Ganesan
    Thirunarayanan, Ganesamoorthy
    Powiązania:
    https://bibliotekanauki.pl/articles/763969.pdf
    Data publikacji:
    2015
    Wydawca:
    Uniwersytet Marii Curie-Skłodowskiej. Wydawnictwo Uniwersytetu Marii Curie-Skłodowskiej
    Tematy:
    E-imines
    UV
    IR and NMR spectra
    Spectral QSAR study
    Antimicrobial activities
    Opis:
    A series of substituted (E)-N-benzylidene-5-bromopyridin-2-amine compounds have been synthesized from 5-bromo-2-aminopyridine with different substituted benzaldehydes. The structure of the adducts was confirmed by their physical constants, UV, IR and NMR spectral data. The observed UV absorption maximum λmaxC=N(nm), IR frequencies νC=N(cm-1), The 1H and 13C NMR δ(ppm) chemical shifts values have been correlated with Hammett substituent constants and F and R parameters using single and multi-linear regression analysis. From the results of statistical analysis, the effect of substituents on the spectral data has been studied. The antimicrobial activities of all synthesized imines have been studied using Bauer-Kirby method.
    Źródło:
    Annales Universitatis Mariae Curie-Skłodowska, sectio AA – Chemia; 2015, 70, 2
    2083-358X
    Pojawia się w:
    Annales Universitatis Mariae Curie-Skłodowska, sectio AA – Chemia
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Solid acidic Bentonite/FeCl3 catalysed solvent-free cyclization of some aryl enones: Synthesis and assessment of antimicrobial potentials of some aryl pyrazolines
    Autorzy:
    Thirunarayanan, G.
    Dineshkumar, N.
    Rajarajan, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/1076026.pdf
    Data publikacji:
    2019
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    1
    3
    5-Substituted pyrazolines
    Antimicrobial activities
    Bentonite/FeCl3
    IR and NMR Spectra
    Solvent-free synthesis
    Opis:
    Some aryl pyrazolines including 3-(substituted phenyl)-5-(naphthalen-1-yl)-1-phenyl-4,5-dihydro-1H-pyrazoles were prepared by microwave irradiation promoted cyclization of aryl enones and phenylhydrazine in the presence of solid acidic bentonite/FeCl3 catalyst under solvent-free conditions. In this cyclization the obtained yields are more than 75%. The structural analysis of these pyrazoline derivatives were confirmed through analytical and spectral techniques. The effect of catalyst and solvent on this cyclization also investigated through the obtained yields. The antimicrobial activities of these pyrazoline derivatives were assessed through measurement of mm of zone of inhibition against their micro stains using well known Bauer-Kirby disc diffusion method.
    Źródło:
    World Scientific News; 2019, 117; 14-28
    2392-2192
    Pojawia się w:
    World Scientific News
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Synthesis, effect of substituents and antimicrobial activities of some 4-bromophenyl chalcones
    Autorzy:
    Vijayakumar, S.
    Vanangamudi, G.
    Thirunarayanan, G.
    Powiązania:
    https://bibliotekanauki.pl/articles/1191238.pdf
    Data publikacji:
    2016
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    (E)-1-(4-bromophenyl)-3-(substituted phenyl)-2-propen-1-ones
    UV spectra
    IR spectra
    NMR spectra
    Substituent effects
    Antimicrobial activities
    Opis:
    Elven (E)-1-(4-bromophenyl)-3-(substituted phenyl)-2-propen-1-ones are formed using sodium hydroxide catalyzed Aldol condensation between 4-bromoacetophenone and substituted benzaldehyde. The production of these chalcone compounds are above 90%. These α, β unsaturated ketones were specified by their physical constants and spectral data (UV, IR, 1H and 13C-NMR). Hammett substituted constants (σ, σ+, σI & σR and F and R parameters have been used for correlating the spectral values of these α, β unsaturated ketones by using single and multi-linear regression analysis. The impacts of substituents on the spectral data have been known on statistical analysis. By using Bauer-Kirby method the anti-microbial activities of these (E)-1-(4-bromophenyl)-3-(substituted phenyl)-2-propen-1-ones compounds are estimated.
    Źródło:
    World Scientific News; 2016, 54; 132-152
    2392-2192
    Pojawia się w:
    World Scientific News
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Synthesis, spectral correlation analysis and evaluation of antimicrobial activities of some (E)-1-(2,4-dimethylthiazol-5-yl)-3-phenylprop-2-en-1-ones
    Autorzy:
    Sathiyendiran, V.
    Balaji, S.
    Senbagam, R.
    Vijayakumar, R.
    Manikandan, V.
    Rajarajan, M.
    Muthuvel, I.
    Markandan, R.
    Thirunarayanan, G.
    Powiązania:
    https://bibliotekanauki.pl/articles/1031849.pdf
    Data publikacji:
    2020
    Wydawca:
    Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
    Tematy:
    4-dimethylthiazol enones
    Antimicrobial activities
    Crossed-Aldol condensation
    E-2
    IR and NMR spectra
    Spectral correlation analysis
    Substituent effects
    UV
    Opis:
    In this work, an attempt was made to synthesized (E)-1-(2,4-dimethylthiazol-5-yl)-3-phenylprop-2-en-1-one by cross-aldol condensation reaction of 5′-acetyl-2,4-dimethylthiazole with various substituted Benz aldehyde in the presence base (sodium hydroxide). The synthesized (E)-1-(2,4-dimethylthiazol-5-yl)-3-phenylprop-2-en-1-one derivative was characterized by physical constants, UV, FT-IR, 1H-NMR & 13C-NMR spectral data. All the observed spectral data of substituted (E)-1-(2,4-dimethylthiazol-5-yl)-3-phenylprop-2-en-1-one compounds have been correlated with Hammett substituent constants(σ, σ+, σI & σR) and F and R parameters using single and multi-linear regression analyses and studied for their anti-microbial activities and compared with the standard drugs (Ciprofloxacin). Some compound of the series exhibited promising anti-microbial activity compared to standard drugs (Ciprofloxacin).
    Źródło:
    World Scientific News; 2020, 141; 66-90
    2392-2192
    Pojawia się w:
    World Scientific News
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-6 z 6

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