- Tytuł:
- Computational analysis of Ancylostoma ceylanicum cysteine proteinase
- Autorzy:
-
Baska, P
Wisniewski, M.
Mieszczanek, J.
Wedrychowicz, H. - Powiązania:
- https://bibliotekanauki.pl/articles/839012.pdf
- Data publikacji:
- 2006
- Wydawca:
- Polskie Towarzystwo Parazytologiczne
- Tematy:
-
parasite
parasitic disease
VAST programme
computational analysis
Ancylostoma ceylanicum
vaccine
parasitology
nematode
cysteine proteinase
animal disease
host-parasite interaction - Opis:
- The potential tertiary structure of Ancylostoma ceylanicum cysteine proteinase was obtained by Automatic Program 3D-JIGSAW and used for finding homologues of known structure by VAST program. The results of computational analysis showed the presence of domains recognizing host immunoglobulins. Based on this analysis we suggest that this protein is involved in cleaving of host antibodies and therefore it may be promising vaccine candidate. In this paper we present the computational analysis of parasitic antigen which is very helpful in evaluation of the potential role of this protein.
- Źródło:
-
Annals of Parasitology; 2006, 52, 4
0043-5163 - Pojawia się w:
- Annals of Parasitology
- Dostawca treści:
- Biblioteka Nauki
Artykuł