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Wyszukujesz frazę "thermosensitive polymer - poloxamer 407" wg kryterium: Temat


Wyświetlanie 1-5 z 5
Tytuł:
Selected pharmaceutical properties of thermosensitive hydrophilic gels with hydroxypropylmethylcellulose containing lactic acid complexed with chitosan
Autorzy:
Małolepsza-Jarmołowska, Katarzyna
Powiązania:
https://bibliotekanauki.pl/articles/1035213.pdf
Data publikacji:
2013
Wydawca:
Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
Tematy:
1
2- propylene glycol
glycerol
hydroxypropylmethylcellulose
lactic acid complexed with chitosan
thermosensitive polymer - poloxamer 407
vaginal infections
Opis:
Gels containing lactic acid complexed with chitosan at a stoichiometric ration 1:1 and 2:1 and 5-25% content of polyoxyethylene glycol 200 are able to move from 25 to 30 cm. The addition of 4% hydroxypropylmethylcellulose besides glycerol increases the movability gels containing lactic acid complexed with chitosan in a stoichiometric ration 1:1 from 25 cm to 28 cm and at 2:1 ratio from 27 cm to 30 cm. Higher concentrations of the poloxamer 407: 23 and 25% result in the movability of 24 to 29 cm The addition of 5-25% glycerol decreases the pH of investigated gels from 3.95 to 4.45 (1:1) and from 3.63 to 4.30 (2:1). The addition of 5-25% 1,2-propylene glycol decreases the pH of investigated gels from 4.00 to 4.46 (1:1) and from 3.70 to 4.33 (2:1). The use of hydroxypropylmethylcellulose allowed to obtain physiological range. The addition of hydroxypropylmethylcellulose reduces the pH and maintains high adhesion.
Źródło:
Progress on Chemistry and Application of Chitin and its Derivatives; 2013, 18, 18; 131-138
1896-5644
Pojawia się w:
Progress on Chemistry and Application of Chitin and its Derivatives
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Effect of a dextrane and hydrophilizing substances on the properties of thermosensitive hydrophilic gels containing lactic acid complexed with chitosan
Autorzy:
Małolepsza-Jarmołowska, Katarzyna
Powiązania:
https://bibliotekanauki.pl/articles/1035215.pdf
Data publikacji:
2013
Wydawca:
Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
Tematy:
1
2- propylene glycol
dextrane
glycerol
lactic acid complexed with chitosan
thermosensitive polymer - poloxamer 407
vaginal infections
Opis:
Gels containing lactic acid complexed with chitosan at a stechiometric ratio 1:1 and 2:1 and 5-25% content of PEG-200 reveal pH from 3.42 to 4.95. The addition of 20 – 25% poloxamer 407 increases the pH from 4.55 to 5.30 for 1:1 gels and from 4.00 to 4.85 for 2:1 gels. The addition of 1.0% dextrane decreases the pH of investigated gels from 4.40 to 4.90 (1:1) and from 4.00 to 4.48 (2:1). The addition of poloxamer 407 at concentrations of 20 to 25% increases the dynamic viscosity from 506.14 to 641.20 for 1:1 and from 540.35 to 692.55 for 2:1 ratios. The addition of 1.0% dextrane increases the dynamic viscosity from 665.23 to 750.28 for 1:1 and from 645.50 to 740.16 for 2:1 ratios. The addition of dextrane and glycerol or 1,2-propylene glycol reduces the pH and maintains high adhesion. The use of dextrane and hydrophilizing substances allowed to obtain physiological range pH.
Źródło:
Progress on Chemistry and Application of Chitin and its Derivatives; 2013, 18, 18; 115-122
1896-5644
Pojawia się w:
Progress on Chemistry and Application of Chitin and its Derivatives
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Effect of a polyvinyl alcohol and selected auxiliary substances on the properties of thermosensitive hydrophilic gels containing lactic acid complexed with chitosan
Autorzy:
Małolepsza-Jarmołowska, Katarzyna
Powiązania:
https://bibliotekanauki.pl/articles/1035323.pdf
Data publikacji:
2013
Wydawca:
Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
Tematy:
1
2- propylene glycol
glycerol
lactic acid complexed with chitosan
polyvinyl alcohol
thermosensitive polymer - poloxamer 407
vaginal infections
Opis:
Gels containing lactic acid complexed with chitosan at a stechiometric ratio 1:1 and 2:1 and 5-25% content of PEG-200 reveal pH from 3.42 to 4.95. The addition of 20 – 25% poloxamer 407 increases the pH from 4.55 to 5.30 for 1:1 gels and from 4.00 to 4.85 for 2:1 gels. The addition of 0.5% polyvinyl alcohol decreases the pH of the investigated gels from 4.00 to 4.55 for 1:1 gels and from 3.85 to 4.40 for 2:1 gels. The addition of poloxamer 407 at concentrations of 20 to 25% increases the dynamic viscosity from 506.14 to 641.20 for 1:1 and from 540.35 to 692.55 for 2:1 ratios. The addition of 0.5% polyvinyl alcohol increases the dynamic viscosity from 590.20 to 720.63 for 1:1 and from 560.90 to 698.82 for 2:1 ratios. The addition of polyvinyl alcohol and auxiliary substances reduces the pH and maintains high adhesion.
Źródło:
Progress on Chemistry and Application of Chitin and its Derivatives; 2013, 18, 18; 107-114
1896-5644
Pojawia się w:
Progress on Chemistry and Application of Chitin and its Derivatives
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Pharmaceutical assessment of thermosensitive hydrophilic gels with polyvinyl pyrrolidone k-30 containing lactic acid complexed with chitosan
Autorzy:
Małolepsza-Jarmołowska, Katarzyna
Powiązania:
https://bibliotekanauki.pl/articles/1035317.pdf
Data publikacji:
2013
Wydawca:
Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
Tematy:
1
2- propylene glycol
glycerol
lactic acid complexed with chitosan
polyvinyl pyrrolidone K-30
thermosensitive polymer - poloxamer 407
vaginal infections
Opis:
Gels containing lactic acid complexed with chitosan at a stoichiometric ration 1:1 and 2:1 and 5-25% content of polyoxyethylene glycol 200 are able to move from 25 to 30 cm. Measurements performed in a biopharmaceutical model revealed that the addition of 20% poloxamer 407 to gels containing lactic acid complexed with chitosan in a stoichiometric ration 1:1 decreases their movability from 20 to 25 cm and at 2:1 ratio, from 22 to 28 cm. Higher concentrations of the poloxamer 407: 23 and 25% result in the movability of 20 to 24 cm. The addition of 5% PVP K-30 besides 1,2-propylene glycol increases the movability gels containing lactic acid complexed with chitosan in a stoichiometric ration 1:1 from 24 cm to 28 cm and at 2:1 ratio from 26 cm to 30 cm. Higher concentrations of the poloxamer 407: 23 and 25% result in the movability of 24 to 27 cm
Źródło:
Progress on Chemistry and Application of Chitin and its Derivatives; 2013, 18, 18; 123-131
1896-5644
Pojawia się w:
Progress on Chemistry and Application of Chitin and its Derivatives
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Assessment of pharmaceutical properties of gynaecological hydrophilic gels containing lactic acid complexed with chitosan
Autorzy:
Małolepsza-Jarmołowska, Katarzyna
Powiązania:
https://bibliotekanauki.pl/articles/1035397.pdf
Data publikacji:
2012
Wydawca:
Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
Tematy:
1
2- propylene glycol
anti-inflammatory drugs.
glycerol
lactic acid complexed with chitosan
thermosensitive polymer - poloxamer 407
vaginal infections
Opis:
Gels containing lactic acid complexed with chitosan at a stoichiometric ration 1:1 and 2:1 and 5-25% content of polyoxyethylene glycol 200 are able to move from 25 to 30 cm. The addition of glycerol increases the movability gels containing lactic acid complexed with chitosan in a stoichiometric ration 1:1 from 23 cm to 26 cm and at 2:1 ratio from 25 cm to 29 cm. Gels with addition 20-25% poloxamer 407 containing lactic acid complexed with chitosan and 5-25% content of glycerol reveal pH from 4.25 to 4.98 for 1:1 and from 3.60 to 4.45 for 2:1. The investigations showed that the addition of a thermosensitive polymer increases the adhesive properties of the investigated gels, but at the same time it increases their pH. The addition of glycerol or 1,2-propylene glycol reduces the pH and maintains high adhesion. The use of hydrofilizing substances allowed to obtain physiological range pH gynaecological gels.
Źródło:
Progress on Chemistry and Application of Chitin and its Derivatives; 2012, 17; 117-124
1896-5644
Pojawia się w:
Progress on Chemistry and Application of Chitin and its Derivatives
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-5 z 5

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