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Wyszukujesz frazę "Kulak, D." wg kryterium: Autor


Wyświetlanie 1-9 z 9
Tytuł:
The physical and occupational activity of patients with multiple sclerosis depending on the form of clinical disease
Autorzy:
Wyszyńska, E.
Sienkiewicz, D.
Kułak, W.
Powiązania:
https://bibliotekanauki.pl/articles/1918844.pdf
Data publikacji:
2019-08-26
Wydawca:
Uniwersytet Medyczny w Białymstoku
Tematy:
Multiple sclerosis
physical activity
occupational activity
Opis:
Introduction: The progressive nature of multiple sclerosis (MS) is associated with numerous neurological deficits, leading gradually to deteriorating health and to disability. Purpose: The aim of this study was a subjective assessment of the physical and occupational activity of individuals with MS depending on the clinical form of the disease. Materials and methods: We used the original to conduct the research, with 28 closed questions. The study was carried out from December 1, 2018, to January 31, 2019, following approval by the Bioethics Committee of the Medical University of Bialystok, among persons belonging to the Association for Helping Sick People for Multiple Sclerosis in Białystok and patients of the Neurology Department of the University Clinical Hospital in Bialystok. The study sample comprised 50 people diagnosed with MS, 41 women and 9 men. Results: The most frequently occurring clinical form of MS was relapsing-remitting (68%). In this form, most participants had good physical fitness (44%). In those with the progressive-recurrent form (50%), very poor physical fitness was subjectively noted. Of those with the relapsing-remitting type of MS, 50% were professionally active, while none of the participants with the progressive-recurrent form were. Both the physical and occupational activities of MS patients were frequently limited by fatigue, balance disturbances, and movement difficulties. Fatigue was the most common symptom for most individuals with MS (82%). Conclusion: MS has a significant impact on both the physical activity and occupational functioning of patients. In the clinical form of MS, relapsing-remitting, patients’ physical fitness was better.
Źródło:
Progress in Health Sciences; 2019, 1; 126-131
2083-1617
Pojawia się w:
Progress in Health Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Granulocyte colony-stimulating factor potential use in the treatment of children with cerebral palsy
Autorzy:
Paszko-Patej, G.
Sienkiewicz, D.
Okurowska-Zawada, B.
Kułak, W.
Powiązania:
https://bibliotekanauki.pl/articles/1918437.pdf
Data publikacji:
2017
Wydawca:
Uniwersytet Medyczny w Białymstoku
Tematy:
Granulocyte colony-stimulating factor
neuroprotection
studies
cerebral palsy
Opis:
Granulocyte colony-stimulating factor (G-CSF) is a glycoprotein that stimulates the bone marrow to produce granulocytes and stem cells and release them into the blood. Recent studies demonstrated the presence of CSF-receptor (G-CSFR) system in the brain and spinal cord, and their roles in neuroprotection and neural tissue repair, as well as improvement in functional recovery. G-CSF exerts neuroprotective actions through the inhibition of apoptosis and inflammation, and the stimulation of neurogenesis. This review highlights recent studies on the potential use of G-CSF in cerebral palsy.
Źródło:
Progress in Health Sciences; 2017, 7(1); 187-192
2083-1617
Pojawia się w:
Progress in Health Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Effects of short moderate exercise on hematological parameters and stem cells in healthy humans
Autorzy:
Sochoń, K.
Sienkiewicz, D.
Okurowska-Zawada, B.
Paszko-Patej, G.
Wojtkowski, J.
Dmitruk, E.
Żak, J
Kułak, W.
Powiązania:
https://bibliotekanauki.pl/articles/1918279.pdf
Data publikacji:
2016
Wydawca:
Uniwersytet Medyczny w Białymstoku
Tematy:
Exercise
healthy subjects
stem cells
Opis:
Introduction: Exercise at various durations and intensities impact on blood and stem cells. This pilot study examined the effects of 30 minutes of treadmill walking on hematological indices and progenitor stem cells CD34+ in healthy subjects. Materials and methods: A total of 17 non-smoking, healthy students, aged 20 to 22 years participated. Hemoglobin, hematocrit, white blood cells, platelets, and stem cell CD34+ numbers were assessed before and after moderate exercise. Statistical analyses examined the relationships between CD34+ cells versus hematological indices, age, and body mass index. Results: Following exercise, significant increases were observed in leukocytes, neutrophils, eosinophils, and CD34+ cells numbers. For CD34+ cells, a fourfold increase was seen. Significant correlations between CD34+ cells, white blood cells, and neutrophils were found. Conclusion: Our results suggest that moderate exercise has a physiological impact on hematologic parameters and stem cells CD34+ in healthy subjects. Furthermore, our findings suggest that brief treadmill exercise may enhance tissue repair mechanisms so important in physiotherapy.
Źródło:
Progress in Health Sciences; 2016, 6(2); 184-187
2083-1617
Pojawia się w:
Progress in Health Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Safety and efficacy of granulocyte colony stimulating factor in a patient with tetraplegia caused by cervical hyperextension injury: a case report
Autorzy:
Okurowska-Zawada, B
Kułak, W
Sienkiewicz, D
Paszko-Patej, G
Dmitruk, E
Kalinowska, A
Wojtkowski, J
Korzeniecka–Kozerska, A
Powiązania:
https://bibliotekanauki.pl/articles/1916580.pdf
Data publikacji:
2014
Wydawca:
Uniwersytet Medyczny w Białymstoku
Tematy:
Cervical hyperextesniosn
spinal cord injury
tetraplegia
male
Opis:
he authors present the case of a 17-year-old boy who suffered a cervical spinal injury as a result of the sharp bending of the head after slipping (without falling). After about 30 minutes, he began to feel tingling in the limbs and he developed tetraparesis. He went through physical rehabili-tation, psychological rehabilitation, occupational therapy, and periodic catheterization. Additionally, we introduced to him a low dose of analog granulocyte colony-stimulating factor (G-CSF). G-CSF 5 μg/kg was given subcutaneously daily for 5 days per month for 3 months, again after 6 months, and again after 10 months. The boy could sit indecently and walk with assistance. A significant increase in muscle strength in this patient with tetraplegia after 10 months of treatment may indicate beneficial effects of G-CSF in this disorder.
Źródło:
Progress in Health Sciences; 2014, 4, 2; 181-184
2083-1617
Pojawia się w:
Progress in Health Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Effects of granulocyte colony-stimulating factor therapy for osteogenesis imperfecta: a case report
Autorzy:
Paszko-Patej, G.
Sienkiewicz, D.
Kułak, W.
Okurowska-Zawada, B.
Wojtkowski, J.
Kalinowska, A.
Okulczyk, K.
Sochoń, K.
Dmitruk, E.
Mirska, A.
Powiązania:
https://bibliotekanauki.pl/articles/1918408.pdf
Data publikacji:
2017
Wydawca:
Uniwersytet Medyczny w Białymstoku
Tematy:
Osteogenesis imperfecta
granulocyte colony-stimulating factor
muscle strength
Opis:
Introduction: Osteogenesis imperfecta (OI) is a genetic disorder of increased bone fragility and low bone mass. OI type IV. Materials and methods: We examined the safety and effectiveness of a low dose of analog granulocyte colony-stimulating factor (G-CSF) in a 15-year-old girl OI type IV. G-CSF 5 μg/kg was given subcutaneously, for 5 days/month for 3, 6 and 12 months. Laboratory tests, including blood, biochemical tests were performed, in addition to clinical examination.Results: Clinical examination revealed an increase of muscle strength in the upper and lower limbs between base line and day 6 and 12 months. We found no serious adverse events. Leukocyte levels remained below 38,000/μL. Low dose G-CSF was safe and well tolerated by the patient. Conclusions: A significant increase in muscle strength in this patient may indicate beneficial effects of G-CSF factor in this disorder. These results are inspiring and warrant further studies.
Źródło:
Progress in Health Sciences; 2017, 7(1); 205-208
2083-1617
Pojawia się w:
Progress in Health Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Effects of granulocyte colony-stimulating factor treatment in children and patients with cerebral palsy: a preliminary report
Autorzy:
Paszko-Patej, G.
Kułak, W.
Okurowska-Zawada, B.
Sienkiewicz, D.
Wojtkowski, J.
Sochoń, K.
Kalinowska, A.
Okulczyk, K.
Topór, E.
Mirska, A.
Powiązania:
https://bibliotekanauki.pl/articles/1918403.pdf
Data publikacji:
2017
Wydawca:
Uniwersytet Medyczny w Białymstoku
Tematy:
Granulocyte colony-stimulating factor
children
cerebral palsy
Opis:
Introduction: Recent reports have revealed that neuroinflammation and apoptosis in brains affected by cerebral palsy could be therapeutic targets. Granulocyte colony-stimulating factor (G-CSF) exerts anti-inflammatory and antiapoptosis effects and stimulates the proliferation of neural stem and progenitor cells in the brain. Purpose: To assess the efficacy and safety of G-CSF treatment in children and adolescents with CP. Materials and methods: Six patients with spastic tetraplegia CP aged 3-15 years were enrolled in this study. Five patients had GMFCS (Gross Motor Function Classification System) level at V, three children had epilepsy, and three had severe mental retardation. We used the gross motor function measure-66 (GMFM-66) to assess motor function.GCSF (5μg/kg/body/day) was administered subcutaneously for five consecutive days during the four months. The parents also evaluated the physical and mental development of their children. Results: We observed improvement in motor function in patients with CP on the GMFM-66 scale. Parents reported improvement in behavior, speech development, and a decrease in spasticity in children with CP. G-CSF therapy was well-tolerated. No side effects were observed during the study. Conclusions: Our preliminary report suggests that G-CSF treatment improves motor and mental function in patients with CP. Further studies are needed to confirm these observations
Źródło:
Progress in Health Sciences; 2017, 7(1); 78-82
2083-1617
Pojawia się w:
Progress in Health Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Quality of life of children suffering from motor disabilities as evaluated by their parents
Autorzy:
Wojtkowski, J.
Sienkiewicz, D.
Okurowska-Zawada, B.
Paszko-Patej, G.
Konopka, A.
Okulczyk, K.
Średzińska, K.
Dmitruk, E.
Mirska, A.
Kułak, W.
Powiązania:
https://bibliotekanauki.pl/articles/1918580.pdf
Data publikacji:
2018-01-09
Wydawca:
Uniwersytet Medyczny w Białymstoku
Tematy:
Quality of life
motor disability
children
parents
Opis:
Purpose: We assessed the quality of life of children with motor disabilities in comparison with healthy children, as evaluated by their parents, using the CHQ-PF28 questionnaire (Child Health Questionnaire—Parent Form). Materials and methods: In a prospective study, we evaluated the quality of life of 105 children with motor disabilities. Results: Our research showed lower quality of life in the group of children with motor disabilities compared with controls, both in terms of physical and psychosocial health. Significant correlations between independent walking and physical functioning, general behavior, and mental health of children suffering from motor disabilities were found. According to the average indices of quality of life of children suffering from motor disabilities, depending on sex, the greatest differences occurred in behavior and change of health status, while the smallest differences in self-esteem and parental involvement, compared with controls. In the case of healthy children, the largest differences appeared in the perception of pain, behavior, and self-esteem; whereas, the smallest variations occurred in the change of health status and physical activity. Conclusion: Children suffering from motor disabilities demonstrate lower quality of life compared with healthy children.
Źródło:
Progress in Health Sciences; 2017, 7(2); 60-66
2083-1617
Pojawia się w:
Progress in Health Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Validation of the Polish version of the Anderson and Dedrick Trust in Physician scale
Autorzy:
Krajewska-Kułak, E.
Kułak, W.
Łukaszuk, C.
Lewko, J.
Sengupta, P.
Cybulski, M.
Guzowski, A.
Kowalczuk, K.
Jankowiak, B.
Kowalewska, B.
Kondzior, D.
Rolka, H.
Baranowska, A.
Lankau, A.
Klimaszewska, K.
Sierakowska, M.
Krajewska-Ferishah, K.
Szyszko-Perłowska, A.
Powiązania:
https://bibliotekanauki.pl/articles/1918629.pdf
Data publikacji:
2018-06-18
Wydawca:
Uniwersytet Medyczny w Białymstoku
Tematy:
Trust in Physician Scale
validation
Polish version
Opis:
Purpose: The aim of this study was to validate the Trust in Physician Scale (TPS) for Polish patients. Materials and Methods: The validation of a Polish-language version of Anderson and Dedrick’s TPS was performed with a group of 849 patients. Validation consisted of the translation and evaluation of the psychometric properties of the Polish TPS and its application among Polish-speaking patients. We also explored the TPS with the patient’s sex, age, education, income, marital status, and number of physician visits. Results: The internal consistency of the Polish TPS was high (Cronbach’s alpha = .891). In our study, the TPS is positively associated with age, education, income, marital status, and number of physician visits. Also, we have found that the TPS is negatively associated with sex and place of residence. Conclusions: The Polish-language scale fulfills all the criteria of psychometric and functional validation with the original version of the Trust in Physician Scale.
Źródło:
Progress in Health Sciences; 2018, 8(1); 27-35
2083-1617
Pojawia się w:
Progress in Health Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Granulocyte colony-stimulating factor therapy for facioscapulohumeral dystrophy: a case report
Autorzy:
Sienkiewicz, D.
Kułak, W.
Okurowska-Zawada, B.
Paszko-Patej, G.
Wojtkowski, J.
Dmitruk, E.
Okulczyk, K.
Sochoń, K.
Kalinowska, A.
Żak, J.
Pogorzelski, R.
Powiązania:
https://bibliotekanauki.pl/articles/1918329.pdf
Data publikacji:
2016
Wydawca:
Uniwersytet Medyczny w Białymstoku
Tematy:
Facioscapulohumeral dystrophy
granulocyte colony-stimulating factor
muscle strength
Opis:
We examined the safety and effectiveness of a low dose of analog granulocyte-colony stimulating factor in a 15-year-old boy with facioscapulohumeral dystrophy. The onset of disease was noted at 12 years of age. The physical examination noted general muscle atrophy more pronounced at left side of the body. He was able to walk 300 meters within 6 minute walk test. Granulocyte colony-stimulating factor 5 μg/kg was given subcutaneously daily for 5 days/month for 1, 2, 3, 6 and 12 months. Clinical examination, laboratory tests including blood, biochemical tests, and CD34+ cells were performed. A significant increase of muscle strength in the lower and upper limbs between baseline, and after 3 months of treatment, after 6, and after 12 months was found. He was able to walk 480 meters within 6 minutes after 12 months. Electromyography demonstrated increase of amplitude in the examined in upper and lower limbs after six months compared to baseline. Leukocyte levels remained below 25000/μL. CD34+ increased significantly at day 5 of granulocyte colony-stimulating factor admini-stration. It was safe and well tolerated by the patient. A significant increase in muscle strength in this patient with facioscapulohumeral dystrophy after 3 months of treatment, after 6, and after 12 months since the first treatment course was completed may indicate beneficial effects of granulocyte colony-stimulating factor in this disorder.
Źródło:
Progress in Health Sciences; 2016, 6(2); 175-177
2083-1617
Pojawia się w:
Progress in Health Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-9 z 9

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